PDB: 345 件ウェブページステータス検索Chemie searchBIRD

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2A68	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic rifabutin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-01 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
4JK1	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4JK2	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.201 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4KI2	Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA 分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2013-05-01 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr.,Sect.F, 69, 2013
2A6H	Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis of transcription inhibition by antibiotic streptolydigin. Mol.Cell, 19, 2005
2A69	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-07-02 公開日 2005-09-20 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins. Cell(Cambridge,Mass.), 122, 2005
2BE5	Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with inhibitor tagetitoxin 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Vassylyev, D.G, Svetlov, V, Vassylyeva, M.N, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Artsimovitch, I, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2005-10-22 公開日 2005-11-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for transcription inhibition by tagetitoxin Nat.Struct.Mol.Biol., 12, 2005
7KHE	Escherichia coli RNA polymerase and rrnBP1 promoter pre-open complex with DksA/ppGpp 分子名称: CHAPSO, DNA (46-MER), DNA (54-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-21 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHB	Escherichia coli RNA polymerase and rrnBP1 promoter open complex 分子名称: CHAPSO, DNA (60-MER), DNA (64-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-20 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.53 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHC	Escherichia coli RNA polymerase and rrnBP1 promoter closed complex 分子名称: CHAPSO, DNA (18 MER), DNA (63-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-20 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.14 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KHI	Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp 分子名称: CHAPSO, DNA (28-MER), DNA (36-MER), ... 著者 Shin, Y, Qayyum, M.Z, Murakami, K.S. 登録日 2020-10-21 公開日 2020-10-28 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.62 Å) 主引用文献 Structural basis of ribosomal RNA transcription regulation. Nat Commun, 12, 2021
7KIN	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter 分子名称: DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIM	Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor 分子名称: DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.38 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
7KIF	Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor 分子名称: DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2020-10-23 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
8VJL	SpoIVFB:pro-sigmaK complex 分子名称: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Lauryl Maltose Neopentyl Glycol, RNA polymerase sigma factor, ... 著者 Orlando, M.A, Pouillon, H.J.T, Mandal, S, Kroos, L, Orlando, B.J. 登録日 2024-01-07 公開日 2024-10-02 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Substrate engagement by the intramembrane metalloprotease SpoIVFB. Nat Commun, 15, 2024
8VJM	SpoIVFB(E44Q variant):pro-sigmaK complex 分子名称: DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Lauryl Maltose Neopentyl Glycol, RNA polymerase sigma-K factor, ... 著者 Orlando, M.A, Pouillon, H.J.T, Mandal, S, Kroos, L, Orlando, B.J. 登録日 2024-01-07 公開日 2024-10-02 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Substrate engagement by the intramembrane metalloprotease SpoIVFB. Nat Commun, 15, 2024
8X6G	Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex 分子名称: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yuan, L, Xu, L, Liu, Q, Feng, Y. 登録日 2023-11-21 公開日 2024-06-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
8X6F	Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex 分子名称: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yuan, L, Xu, L, Liu, Q, Feng, Y. 登録日 2023-11-21 公開日 2024-06-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
8W8N	Thermus thermophilus initiation transcription complex in the pre-translocated state 分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.693 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8W8P	Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (21-MER), DNA (27-MER), ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (3.165 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8W8O	Thermus thermophilus initiation complex in the half-translocated state 分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.512 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8Y6U	Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Shi, J. 登録日 2024-02-03 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 NMR analysis of a loop-bulge structure of UUCGA pentaloop. Biochem.Biophys.Res.Commun., 691, 2024
8Z6G	the AlgU-MucAcyto complex structure in Pseudomonas aeruginosa 分子名称: Anti sigma-E RseA, N-terminal domain protein, RNA polymerase sigma factor 著者 Li, T, Wang, Y.Z, Bao, R. 登録日 2024-04-19 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.10109687 Å) 主引用文献 the AlgU-MucAcyto complex structure in Pseudomonas aeruginosa To Be Published
7L7B	Clostridioides difficile RNAP with fidaxomicin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J. 登録日 2020-12-28 公開日 2022-02-02 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature, 604, 2022
7MLB	Crystal structure of Thermus thermophilus transcription initiation complex with 5nt RNA 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*AP*GP*GP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*CP*AP*TP*CP*CP*CP*TP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Liu, Y, Ebright, R.H. 登録日 2021-04-28 公開日 2022-02-02 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and mechanistic basis of reiterative transcription initiation. Proc.Natl.Acad.Sci.USA, 119, 2022

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