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1OC4
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Lactate dehydrogenase from Plasmodium berghei
分子名称: GLYCEROL, L-LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Winter, V.J, Brady, R.L.
登録日2003-02-05
公開日2003-09-18
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Plasmodium Berghei Lactate Dehydrogenase Indicates the Unique Structural Differences of These Enzymes are Shared Across the Plasmodium Genus
Mol.Biochem.Parasitol., 131, 2003
3NEP
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BU of 3nep by Molmil
1.55A resolution structure of malate dehydrogenase from Salinibacter ruber
分子名称: Malate dehydrogenase
著者Coquelle, N, Madern, D.
登録日2010-06-09
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.551 Å)
主引用文献Gradual adaptive changes of a protein facing high salt concentrations.
J.Mol.Biol., 404, 2010
6ITL
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BU of 6itl by Molmil
Crystal structure of malate dehydrogenase from Mannheimia succiniciproducens in complex with NAD
分子名称: GLYCEROL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Seo, H, Kim, K.-J.
登録日2018-11-23
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase.
Nat Commun, 11, 2020
1PZE
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T.gondii LDH1 apo form
分子名称: lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
5K0Z
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BU of 5k0z by Molmil
Cryo-EM structure of lactate dehydrogenase (LDH) in inhibitor-bound state
分子名称: L-lactate dehydrogenase B chain
著者Merk, A, Bartesaghi, A, Banerjee, S, Falconieri, V, Rao, P, Earl, L, Milne, J, Subramaniam, S.
登録日2016-05-17
公開日2016-06-08
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell, 165, 2016
1PZG
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T.gondii LDH1 complexed with APAD and sulfate at 1.6 Angstroms
分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, SULFATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
1PZF
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T.gondii LDH1 ternary complex with APAD+ and oxalate
分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
7F8D
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Malate Dehydrogenase from Geobacillus stearothermophilus (gs-MDH) G218Y mutant
分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Shimozawa, Y, Himiyama, T, Nakamura, T, Nishiya, Y.
登録日2021-07-02
公開日2022-02-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Increasing loop flexibility affords low-temperature adaptation of a moderate thermophilic malate dehydrogenase from Geobacillus stearothermophilus.
Protein Eng.Des.Sel., 34, 2021
7EPM
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human LDHC complexed with NAD+ and ethylamino acetic acid
分子名称: 2-(ethylamino)-2-oxidanylidene-ethanoic acid, L-lactate dehydrogenase C chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Yu, Y, Chen, Q.
登録日2021-04-27
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of human LDHC4 as a potential target for anticancer drug discovery.
Acta Pharm Sin B, 12, 2022
6J9D
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Babesia microti lactate dehydrogenase R99A (BmLDHR99A)
分子名称: L-lactate dehydrogenase
著者Yu, L.
登録日2019-01-22
公開日2019-10-16
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.904 Å)
主引用文献Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis.
Faseb J., 33, 2019
2FN7
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BU of 2fn7 by Molmil
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (lactic acid) and cofactor (b-nicotinamide adenine dinucleotide)
分子名称: GLYCEROL, LACTIC ACID, Lactate Dehydrogenase, ...
著者Senkovich, O.A, Chattopadhyay, D.
登録日2006-01-10
公開日2007-01-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of cryptosporidium parvum lactate dehydrogenase in complex with substrates and cofactors
To be Published
1PZH
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T.gondii LDH1 ternary complex with NAD and oxalate
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXALATE ION, lactate dehydrogenase
著者Kavanagh, K.L, Elling, R.A, Wilson, D.K.
登録日2003-07-10
公開日2004-02-24
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Toxoplasma gondii LDH1: Active-Site Differences from Human Lactate Dehydrogenases and the Structural Basis for Efficient APAD+ Use.
Biochemistry, 43, 2004
3PQE
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Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation
分子名称: L-lactate dehydrogenase
著者Zhang, Y, Garavito, R.M.
登録日2010-11-26
公開日2011-12-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of L-lactate dehydrogenase from Bacillus subtilis with H171C mutation
To be Published
3PQF
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Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+
分子名称: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, Y, Garavito, R.M.
登録日2010-11-26
公開日2012-01-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Crystal structure of L-lactate dehydrogenase from Bacillus subtilis mutation H171C complexed with NAD+
To be Published
1O6Z
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1.95 A resolution structure of (R207S,R292S) mutant of malate dehydrogenase from the halophilic archaeon Haloarcula marismortui (holo form)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Irimia, A, Ebel, C, Madern, D, Richard, S.B, Cosenza, L.W, Zaccai, G, Vellieux, F.M.D.
登録日2002-10-22
公開日2003-02-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Oligomeric States of Haloarcula Marismortui Malate Dehydrogenase are Modulated by Solvent Components as Shown by Crystallographic and Biochemical Studies
J.Mol.Biol., 326, 2003
3PQD
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BU of 3pqd by Molmil
Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Zhang, Y, Garavito, R.M.
登録日2010-11-26
公開日2012-01-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.376 Å)
主引用文献Crystal structure of L-lactate dehydrogenase from Bacillus subtilis complexed with FBP and NAD+
To be Published
1WZI
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BU of 1wzi by Molmil
Structural basis for alteration of cofactor specificity of Malate dehydrogenase from Thermus flavus
分子名称: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
登録日2005-03-05
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for alteration of cofactor specificity of malate dehydrogenase from Thermus flavus
to be published
1Y6J
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L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135
分子名称: L-lactate dehydrogenase
著者Chen, L, Yang, H, Kataeva, I, Chen, L.R, Tempel, W, Lee, D, Habel, J, Zhou, W, Lin, D, Ljungdahl, L, Liu, Z.-J, Rose, J, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2004-12-06
公開日2004-12-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献L-Lactate Dehydrogenase from Clostridium Thermocellum Cth-1135
To be Published
1Y7T
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Crystal structure of NAD(H)-depenent malate dehydrogenase complexed with NADPH
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Tomita, T, Fushinobu, S, Kuzuyama, T, Nishiyama, M.
登録日2004-12-10
公開日2005-08-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of NAD-dependent malate dehydrogenase complexed with NADP(H)
Biochem.Biophys.Res.Commun., 334, 2005
1XIV
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Plasmodium falciparum lactate dehydrogenase complexed with 2-({4-chloro-[hydroxy(methoxy)methyl]cyclohexyl}amino)ethane-1,1,2-triol
分子名称: 2-({4-CHLORO-2-[HYDROXY(METHOXY)METHYL]CYCLOHEXYL}AMINO)ETHANE-1,1,2-TRIOL, GLYCEROL, L-lactate dehydrogenase
著者Conners, R, Cameron, A, Read, J.A, Schambach, F, Sessions, R.B, Brady, R.L.
登録日2004-09-22
公開日2005-06-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase
MOL.BIOCHEM.PARASITOL., 142, 2005
2A92
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Crystal structure of lactate dehydrogenase from Plasmodium vivax: complex with NADH
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
2A94
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Structure of Plasmodium falciparum lactate dehydrogenase complexed to APADH.
分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-11
公開日2006-01-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
2AA3
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Crystal structure of Plasmodium vivax lactate dehydrogenase complex with APADH
分子名称: ACETYL PYRIDINE ADENINE DINUCLEOTIDE, REDUCED, L-lactate dehydrogenase, ...
著者Chaikuad, A, Fairweather, V, Conners, R, Joseph-Horne, T, Turgut-Balik, D, Brady, R.L.
登録日2005-07-13
公開日2006-01-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of Lactate Dehydrogenase from Plasmodium vivax: Complexes with NADH and APADH.
Biochemistry, 44, 2005
2J5K
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2.0 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui (radiation damage series)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE
著者Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
登録日2006-09-18
公開日2006-09-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007
2J5R
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2.25 A resolution structure of the wild type malate dehydrogenase from Haloarcula marismortui after second radiation burn (radiation damage series)
分子名称: CHLORIDE ION, MALATE DEHYDROGENASE
著者Fioravanti, E, Vellieux, F.M.D, Amara, P, Madern, D, Weik, M.
登録日2006-09-19
公開日2006-09-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Specific Radiation Damage to Acidic Residues and its Relation to Their Chemical and Structural Environment.
J.Synchrotron Radiat., 14, 2007

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