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8J57
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BU of 8j57 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with bedaquiline(BDQ)
分子名称: ATP synthase subunit a, ATP synthase subunit c, Bedaquiline
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-21
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8J58
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BU of 8j58 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in the apo-form
分子名称: ATP synthase subunit a, ATP synthase subunit c
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-21
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8J0S
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BU of 8j0s by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with bedaquiline(BDQ)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-11
公開日2024-05-22
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8JR0
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BU of 8jr0 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with TBAJ-587
分子名称: (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-06-15
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8KHF
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BU of 8khf by Molmil
Structure of the human ATP synthase bound to bedaquiline (membrane domain)
分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ...
著者Lai, Y, Zhang, Y.
登録日2023-08-21
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8JR1
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BU of 8jr1 by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase Fo in complex with TBAJ-587
分子名称: (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol, ATP synthase subunit a, ATP synthase subunit c
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-06-15
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8KI3
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BU of 8ki3 by Molmil
Structure of the human ATP synthase bound to bedaquiline (composite)
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ...
著者Lai, Y, Zhang, Y, Gong, H.
登録日2023-08-22
公開日2024-05-01
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
8J0T
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BU of 8j0t by Molmil
Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in the apo-form
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H.
登録日2023-04-11
公開日2024-05-22
最終更新日2024-08-21
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587.
Nature, 631, 2024
5ARH
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BU of 5arh by Molmil
Bovine mitochondrial ATP synthase state 2a
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-24
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
5ARA
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BU of 5ara by Molmil
Bovine mitochondrial ATP synthase state 1a
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-24
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
5ARI
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BU of 5ari by Molmil
Bovine mitochondrial ATP synthase state 2b
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-24
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.4 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
5ARE
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BU of 5are by Molmil
Bovine mitochondrial ATP synthase state 1b
分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ...
著者Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L.
登録日2015-09-24
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.7 Å)
主引用文献Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM.
Elife, 4, 2015
5DN6
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BU of 5dn6 by Molmil
ATP synthase from Paracoccus denitrificans
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F0 subcomplex C subunit, ...
著者Morales-Rios, E, Montgomery, M.G, Leslie, A.G.W, Walker, J.E.
登録日2015-09-09
公開日2015-10-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.98 Å)
主引用文献Structure of ATP synthase from Paracoccus denitrificans determined by X-ray crystallography at 4.0 angstrom resolution.
Proc.Natl.Acad.Sci.USA, 112, 2015
6WM2
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BU of 6wm2 by Molmil
Human V-ATPase in state 1 with SidK and ADP
分子名称: (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid, 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, L, Wu, H, Fu, T.M.
登録日2020-04-20
公開日2020-11-11
最終更新日2020-11-25
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WM3
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BU of 6wm3 by Molmil
Human V-ATPase in state 2 with SidK and ADP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ...
著者Wang, L, Wu, H, Fu, T.M.
登録日2020-04-20
公開日2020-11-11
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WNQ
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BU of 6wnq by Molmil
E. coli ATP Synthase State 2a
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Stewart, A.G, Sobti, M, Walshe, J.L.
登録日2020-04-23
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch.
Nat Commun, 11, 2020
6WNR
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BU of 6wnr by Molmil
E. coli ATP synthase State 3b
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ...
著者Stewart, A.G, Sobti, M, Walshe, J.L.
登録日2020-04-23
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch.
Nat Commun, 11, 2020
6XBY
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BU of 6xby by Molmil
Cryo-EM structure of V-ATPase from bovine brain, state 2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wang, R, Li, X.
登録日2020-06-07
公開日2020-08-19
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Cryo-EM structures of intact V-ATPase from bovine brain.
Nat Commun, 11, 2020
6WM4
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BU of 6wm4 by Molmil
Human V-ATPase in state 3 with SidK and ADP
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Renin receptor, ...
著者Wang, L, Wu, H, Fu, T.M.
登録日2020-04-20
公開日2020-11-11
最終更新日2020-11-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.
Mol.Cell, 80, 2020
6WTD
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BU of 6wtd by Molmil
Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of Bedaquiline bound
分子名称: ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ...
著者Mueller, D.M, Srivastava, A.P, Symersky, J, Luo, M, Liao, M.F.
登録日2020-05-02
公開日2020-08-26
最終更新日2020-10-07
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Bedaquiline inhibits the yeast and human mitochondrial ATP synthases.
Commun Biol, 3, 2020
6XBW
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BU of 6xbw by Molmil
Cryo-EM structure of V-ATPase from bovine brain, state 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wang, R, Li, X.
登録日2020-06-07
公開日2020-08-19
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Cryo-EM structures of intact V-ATPase from bovine brain.
Nat Commun, 11, 2020
6YNY
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BU of 6yny by Molmil
Cryo-EM structure of Tetrahymena thermophila mitochondrial ATP synthase - F1Fo composite dimer model
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ...
著者Kock Flygaard, R, Muhleip, A, Amunts, A.
登録日2020-04-14
公開日2020-09-30
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.
Nat Commun, 11, 2020
7FDA
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BU of 7fda by Molmil
CryoEM Structure of Reconstituted V-ATPase, state1
分子名称: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
登録日2021-07-16
公開日2021-12-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDC
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BU of 7fdc by Molmil
CryoEM Structures of Reconstituted V-ATPase, state3
分子名称: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
登録日2021-07-16
公開日2021-12-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021
7FDB
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BU of 7fdb by Molmil
CryoEM Structures of Reconstituted V-ATPase,State2
分子名称: Fusion of yeast V-type proton ATPase subunit H(NT) and human V-type proton ATPase subunit H(CT), V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Khan, M.M, Lee, S, Oot, R.A, Couoh-Cardel, S, KIm, H, Wilkens, S, Roh, S.H.
登録日2021-07-16
公開日2021-12-22
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献CryoEM Structures of Reconstituted V-ATPase and Oxr1-bound V1 Reveal a Novel Mechanism of Regulation.
Embo J., 2021

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件を2024-10-16に公開中

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