PDB: 271 件ウェブページステータス検索Chemie searchBIRD

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3K5L	Crystal structure of E.coli Pol II-abasic DNA-dATP Lt(0, 3) ternary complex 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*TP*(3DR)P*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3KD1	Closed binary complex of an RB69 gp43 fingers domain mutant complexed with an acyclic GMP terminated primer template pair. 分子名称: DNA (5'-D(*CP*GP*TP*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(4DG))-3'), DNA polymerase, ... 著者 Zahn, K.E, Doublie, S. 登録日 2009-10-22 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Phosphonoformic acid inhibits viral replication by trapping the closed form of the DNA polymerase. J.Biol.Chem., 286, 2011
3K5M	Crystal structure of E.coli Pol II-abasic DNA-ddGTP Lt(-2, 2) ternary complex 分子名称: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*TP*CP*CP*TP*GP*(3DR)P*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-07 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II. Cell(Cambridge,Mass.), 139, 2009
3K59	Crystal structure of E.coli Pol II-normal DNA-dCTP ternary complex 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*GP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2009-10-06 公開日 2010-02-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
3L8B	Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin 分子名称: DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ... 著者 Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S. 登録日 2009-12-30 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry, 49, 2010
3LDS	Crystal structure of RB69 gp43 with DNA and dATP opposite 8-oxoG 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*(8OG)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*(DDG))-3'), ... 著者 Hogg, M, Midkiff, J, Rudnicki, J, Reha-Krantz, L, Doublie, S, Wallace, S.S. 登録日 2010-01-13 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Kinetics of mismatch formation opposite lesions by the replicative DNA polymerase from bacteriophage RB69. Biochemistry, 49, 2010
8FOJ	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
3MAQ	Crystal structure of E.coli Pol II-normal DNA-dGTP ternary complex 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*TP*GP*CP*CP*TP*AP*GP*CP*GP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*AP*CP*GP*TP*AP*CP*GP*CP*TP*AP*GP*GP*CP*AP*CP*A)-3'), ... 著者 Yang, W, Wang, F. 登録日 2010-03-24 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insight into translesion synthesis by DNA Pol II Cell(Cambridge,Mass.), 139, 2009
8FOH	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOC	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOE	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex bound to a template DNA 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.6 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOD	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in Apo state conformation II 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOK	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the DNA elongation state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
3LZI	RB69 DNA Polymerase (Y567A) ternary complex with dATP Opposite 7,8-dihydro-8-oxoguanine 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. 登録日 2010-03-01 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry, 49, 2010
8G9O	Complete DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8G99	Partial auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase large subunit, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8G9F	Complete auto-inhibitory complex of Xenopus laevis DNA polymerase alpha-primase 分子名称: DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... 著者 Mullins, E.A, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
3NCI	RB69 DNA Polymerase Ternary Complex with dCTP Opposite dG at 1.8 angstrom resolution 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Wang, M, Blaha, G, Steitz, T.A, Konigsberg, W.H, Wang, J. 登録日 2010-06-04 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Insights into base selectivity from the 1.8 A resolution structure of an RB69 DNA polymerase ternary complex. Biochemistry, 50, 2011
8G9L	DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
8G9N	Partial DNA elongation subcomplex of Xenopus laevis DNA polymerase alpha-primase 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... 著者 Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. 登録日 2023-02-21 公開日 2023-04-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
3NHG	RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dTTP Opposite dG 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... 著者 Wang, M, Wang, J, Konigsberg, W.H. 登録日 2010-06-14 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
3NE6	RB69 DNA Polymerase (S565G/Y567A) Ternary Complex with dCTP Opposite dG 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Wang, M, Wang, J, Konigsberg, W.H. 登録日 2010-06-08 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
3NGI	RB69 DNA Polymerase (Y567A) Ternary Complex with dTTP Opposite dG 分子名称: CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), DNA (5'-D(*TP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), ... 著者 Wang, M, Wang, J, Konigsberg, W.H. 登録日 2010-06-11 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.886 Å) 主引用文献 Variation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal Structures. J.Mol.Biol., 406, 2011
3NAE	RB69 DNA Polymerase (Y567A) Ternary Complex with dATP Opposite Guanidinohydantoin 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. 登録日 2010-06-01 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Substitution of Ala for Tyr567 in RB69 DNA Polymerase Allows dAMP and dGMP To Be Inserted opposite Guanidinohydantoin . Biochemistry, 49, 2010
3LZJ	RB69 DNA Polymerase (Y567A) ternary complex with dCTP Opposite 7,8-Dihydro-8-oxoguanine 分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*(DOC))-3'), ... 著者 Wang, M, Beckman, J, Blaha, G, Wang, J, Konigsberg, W.H. 登録日 2010-03-01 公開日 2010-05-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine . Biochemistry, 49, 2010

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