PDB: 143 件ウェブページステータス検索Chemie searchBIRD

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7MIU	Mouse CTPS2 bound to inhibitor R80 分子名称: CTP synthase 2, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MIP	Mouse CTPS1 bound to inhibitor R80 分子名称: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-17 公開日 2021-10-13 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MGZ	Human CTPS1 bound to UTP, AMPPNP, and glutamine 分子名称: CTP synthase 1, GLUTAMINE, MAGNESIUM ION, ... 著者 Lynch, E.M, Dimattia, M.A, Kollman, J.M. 登録日 2021-04-14 公開日 2021-10-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for isoform-specific inhibition of human CTPS1. Proc.Natl.Acad.Sci.USA, 118, 2021
7MO6	Guanosine Monophosphate Synthase from Aspergillus fumigatus Af293 分子名称: GMP synthase [glutamine-hydrolyzing] 著者 Nguyen, S, Bruning, J.B. 登録日 2021-05-01 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta Crystallogr D Struct Biol, 78, 2022
8FV6	E coli. CTP synthase in complex with dF-dCTP 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV8	E coli. CTP synthase in complex with dF-dCTP + ADP 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-DIPHOSPHATE, CTP synthase, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVD	E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 100 mM MgCl2) 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MAGNESIUM ION, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV9	E coli. CTP synthase in complex with F-dCTP 分子名称: 2'-deoxy-2'-fluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVE	E coli. CTP synthase in complex with CTP (potassium malonate + 100 mM MgCl2) 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVC	E coli. CTP synthase in complex with dF-dCTP (potassium malonate + 5 mM MgCl2) 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), CTP synthase, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FV7	E coli. CTP synthase in complex with dF-dCTP + ATP 分子名称: 2'-deoxy-2',2'-difluorocytidine 5'-(tetrahydrogen triphosphate), ADENOSINE-5'-TRIPHOSPHATE, CTP synthase, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVB	E coli. CTP synthase in complex with CTP 分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8FVA	E coli. CTP synthase in complex with F-araCTP 分子名称: 4-amino-1-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CTP synthase, MALONIC ACID, ... 著者 Holyoak, T, McLeod, M.J, Tran, N. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate. Protein Sci., 32, 2023
8HX9	Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae with chorismate 分子名称: (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, 4-amino-4-deoxychorismate synthase, FORMIC ACID, ... 著者 Nakamichi, Y, Watanabe, M. 登録日 2023-01-04 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
8HX6	Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae 分子名称: 4-amino-4-deoxychorismate synthase, D-MALATE, MAGNESIUM ION, ... 著者 Nakamichi, Y, Watanabe, M. 登録日 2023-01-04 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
8HX8	Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae co-crystallized with chorismate 分子名称: 4-amino-4-deoxychorismate synthase, MAGNESIUM ION, SUCCINIC ACID, ... 著者 Nakamichi, Y, Watanabe, M. 登録日 2023-01-04 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
8HX7	Crystal structure of 4-amino-4-deoxychorismate synthase from Streptomyces venezuelae co-crystallized with L-glutamine 分子名称: 4-amino-4-deoxychorismate synthase, CHLORIDE ION, MAGNESIUM ION, ... 著者 Nakamichi, Y, Watanabe, M. 登録日 2023-01-04 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for the allosteric pathway of 4-amino-4-deoxychorismate synthase. Acta Crystallogr D Struct Biol, 79, 2023
8I9O	ecCTPS filament bound with CTP, NADH, DON 分子名称: 5-OXO-L-NORLEUCINE, ADENINE, CTP synthase, ... 著者 Guo, C.J, Liu, J.L. 登録日 2023-02-07 公開日 2024-02-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Filamentation and inhibition of prokaryotic CTP synthase To Be Published

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