PDB: 229 件ウェブページステータス検索Chemie searchBIRD

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6Z7T	Nucleotide-free Myosin-II motor domain 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Ewert, W, Preller, M. 登録日 2020-06-01 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. Int J Mol Sci, 21, 2020
6YCY	Plasmodium falciparum Myosin A full-length, post-rigor state 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Moussaoui, D, Robblee, J.P, Auguin, D, Krementsova, E.B, Robert-Paganin, J, Trybus, K.M, Houdusse, A. 登録日 2020-03-19 公開日 2020-11-11 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Full-length Plasmodium falciparum myosin A and essential light chain PfELC structures provide new anti-malarial targets. Elife, 9, 2020
6YSY	Skeletal Myosin bound to MPH-220, MgADP-VO4 分子名称: (9~{S})-5-methyl-12-(4-morpholin-4-ylphenyl)-9-oxidanyl-4-thia-2,12-diazatricyclo[7.3.0.0^{3,7}]dodeca-1,3(7),5-trien-8-one, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Canon, L, Kikuti, C.M, Gyimesi, M, Malnasi-Csizmadia, A, Houdusse, A. 登録日 2020-04-23 公開日 2021-03-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.246 Å) 主引用文献 Single Residue Variation in Skeletal Muscle Myosin Enables Direct and Selective Drug Targeting for Spasticity and Muscle Stiffness. Cell, 183, 2020
6Z7U	Myosin-II motor domain complexed with blebbistatin in a new ADP-release conformation 分子名称: (-)-1-PHENYL-1,2,3,4-TETRAHYDRO-4-HYDROXYPYRROLO[2,3-B]-7-METHYLQUINOLIN-4-ONE, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Ewert, W, Preller, M. 登録日 2020-06-01 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural and Computational Insights into a Blebbistatin-Bound Myosin•ADP Complex with Characteristics of an ADP-Release Conformation along the Two-Step Myosin Power Stoke. Int J Mol Sci, 21, 2020
6XE9	10S myosin II (smooth muscle) 分子名称: Myosin II heavy chain (smooth muscle), Myosin light chain 9, Myosin light chain smooth muscle isoform 著者 Tiwari, P, Craig, R, Padron, R. 登録日 2020-06-12 公開日 2020-12-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-EM structure of the inhibited (10S) form of myosin II. Nature, 588, 2020
1KK7	SCALLOP MYOSIN IN THE NEAR RIGOR CONFORMATION 分子名称: CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... 著者 Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, A.G, Cohen, C. 登録日 2001-12-06 公開日 2002-10-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
1KK8	SCALLOP MYOSIN (S1-ADP-BeFx) IN THE ACTIN-DETACHED CONFORMATION 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... 著者 Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. 登録日 2001-12-06 公開日 2002-10-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
1KWO	SCALLOP MYOSIN S1-ATPgammaS-p-PDM IN THE ACTIN-DETACHED CONFORMATION 分子名称: 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, CALCIUM ION, MAGNESIUM ION, ... 著者 Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. 登録日 2002-01-30 公開日 2002-11-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Crystallographic findings on the internally uncoupled and near-rigor states of myosin: Further insights into the mechanics of the motor Proc.Natl.Acad.Sci.USA, 99, 2002
6Z2S	Crystal structure of adhibin analogue-bound myosin-2 分子名称: 3,6-dibromo-1-(hydroxymethyl)carbazole, ACETATE ION, ADP METAVANADATE, ... 著者 Ewert, W, Knoelker, H.-J, Tsiavaliaris, G, Preller, M. 登録日 2020-05-18 公開日 2021-06-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells To Be Published
1KQM	SCALLOP MYOSIN S1-AMPPNP IN THE ACTIN-DETACHED CONFORMATION 分子名称: CALCIUM ION, MAGNESIUM ION, MYOSIN ESSENTIAL LIGHT CHAIN, ... 著者 Himmel, D.M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. 登録日 2002-01-07 公開日 2002-11-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystallographic findings on the internally uncoupled and near-rigor states of myosin: Further insights into the mechanics of the motor Proc.Natl.Acad.Sci.USA, 99, 2002
1L2O	SCALLOP MYOSIN S1-ADP-p-PDM IN THE ACTIN-DETACHED CONFORMATION 分子名称: 4-[4-(2,5-DIOXO-PYRROLIDIN-1-YL)-PHENYLAMINO]-4-HYDROXY-BUTYRIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... 著者 Himmel, M, Gourinath, S, Reshetnikova, L, Shen, Y, Szent-Gyorgyi, G, Cohen, C. 登録日 2002-02-22 公開日 2002-10-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic findings on the internally uncoupled and near-rigor states of myosin: further insights into the mechanics of the motor. Proc.Natl.Acad.Sci.USA, 99, 2002
1JWY	CRYSTAL STRUCTURE OF THE DYNAMIN A GTPASE DOMAIN COMPLEXED WITH GDP, DETERMINED AS MYOSIN FUSION 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Niemann, H.H, Knetsch, M.L.W, Scherer, A, Manstein, D.J, Kull, F.J. 登録日 2001-09-05 公開日 2001-11-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a dynamin GTPase domain in both nucleotide-free and GDP-bound forms. EMBO J., 20, 2001
1LVK	X-RAY CRYSTAL STRUCTURE OF THE MG (DOT) 2'(3')-O-(N-METHYLANTHRANILOYL) NUCLEOTIDE BOUND TO DICTYOSTELIUM DISCOIDEUM MYOSIN MOTOR DOMAIN 分子名称: 2'(3')-O-N-METHYLANTHRANILOYL-ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Bauer, C.B, Kuhlman, P.A, Bagshaw, C.R, Rayment, I. 登録日 1997-09-05 公開日 1998-01-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain. J.Mol.Biol., 274, 1997
4P7H	Structure of Human beta-Cardiac Myosin Motor Domain::GFP chimera 分子名称: Myosin-7,Green fluorescent protein, SULFATE ION 著者 Winkelmann, D.A, Miller, M.T, Stock, A.M. 登録日 2014-03-27 公開日 2014-05-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structure of Human beta-Cardiac Myosin Motor Domain at 3.2 A Mol. Biol. Cell, 2011
4PA0	Omecamtiv Mercarbil binding site on the Human Beta-Cardiac Myosin Motor Domain 分子名称: GLYCEROL, Myosin-7,Green fluorescent protein, methyl 4-(2-fluoro-3-{[(6-methylpyridin-3-yl)carbamoyl]amino}benzyl)piperazine-1-carboxylate 著者 Winkelmann, D.A, Miller, M.T, Stock, A.M. 登録日 2014-04-06 公開日 2015-07-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for drug-induced allosteric changes to human beta-cardiac myosin motor activity. Nat Commun, 6, 2015
4PD3	Crystal Structure of Rigor-Like Human Nonmuscle Myosin-2B 分子名称: Nonmuscle myosin heavy chain B, Alpha-actinin A Chimera Protein 著者 Munnich, S, Pathan-Chhatbar, S, Manstein, D.J. 登録日 2014-04-17 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Crystal structure of the rigor-like human non-muscle myosin-2 motor domain. Febs Lett., 588, 2014
4PJK	Dicty myosin II R238E.E459R mutant (with ADP.Pi) in the Pi release state 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. 登録日 2014-05-12 公開日 2015-04-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
4PJJ	MYOSIN VI (MD-INSERT2-CAM, DELTA-INSERT1) post-rigor state - long soaking with PO4 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin, ... 著者 Isabet, T, Benisty, H, Llinas, P, Sweeney, H.L, Houdusse, A. 登録日 2014-05-12 公開日 2015-04-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 How actin initiates the motor activity of Myosin. Dev.Cell, 33, 2015
2W4W	Isometrically contracting insect asynchronous flight muscle quick frozen after a quick stretch step 分子名称: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ... 著者 Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. 登録日 2008-12-02 公開日 2010-08-25 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation. Plos One, 7, 2012
2W4G	ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE QUICK FROZEN AFTER A QUICK STRETCH STEP 分子名称: MYOSIN HEAVY CHAIN, SKELETAL MUSCLE, ADULT, ... 著者 Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. 登録日 2008-11-25 公開日 2010-08-25 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions Plos One, 5, 2010
2W4T	ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE 分子名称: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ... 著者 Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. 登録日 2008-12-02 公開日 2010-01-19 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions Plos One, 5, 2010
2W4V	Isometrically contracting insect asynchronous flight muscle quick frozen after a quick release step 分子名称: MYOSIN ESSENTIAL LIGHT CHAIN, STRIATED ADDUCTOR MUSCLE, MYOSIN HEAVY CHAIN, ... 著者 Wu, S, Liu, J, Reedy, M.C, Tregear, R.T, Winkler, H, Franzini-Armstrong, C, Sasaki, H, Lucaveche, C, Goldman, Y.E, Reedy, M.K, Taylor, K.A. 登録日 2008-12-02 公開日 2010-09-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (35 Å) 主引用文献 Structural Changes in Isometrically Contracting Insect Flight Muscle Trapped Following a Mechanical Perturbation. Plos One, 7, 2012
2VAS	Myosin VI (MD-insert2-CaM, Delta-Insert1) Post-rigor state 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... 著者 Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A. 登録日 2007-09-04 公開日 2007-12-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke. Embo J., 27, 2008
2VB6	Myosin VI (MD-insert2-CaM, Delta Insert1) Post-rigor state (crystal form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, ... 著者 Menetrey, J, Llinas, P, Cicolari, J, Squires, G, Liu, X, Li, A, Sweeney, H.L, Houdusse, A. 登録日 2007-09-06 公開日 2007-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Post-Rigor Structure of Myosin Vi and Implications for the Recovery Stroke. Embo J., 27, 2008
2X9H	CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE 分子名称: 2,3,4,6,8-PENTACHLORO-9H-CARBAZOL-1-OL, ADP METAVANADATE, MAGNESIUM ION, ... 著者 Selvadurai, J, Kirst, J, Knoelker, H.J, Manstein, D.J. 登録日 2010-03-19 公開日 2011-05-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal Structure of Myosin-2 Motor Domain in Complex with Adp-Metavanadate and Pentachlorocarbazole To be Published

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