PDB: 533 件ウェブページステータス検索Chemie searchBIRD

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1A0N	NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE COMPLEXED WITH THE SYNTHETIC PEPTIDE P2L CORRESPONDING TO RESIDUES 91-104 OF THE P85 SUBUNIT OF PI3-KINASE, FAMILY OF 25 STRUCTURES 分子名称: FYN, PRO-PRO-ARG-PRO-LEU-PRO-VAL-ALA-PRO-GLY-SER-SER-LYS-THR 著者 Renzoni, D.A, Pugh, D.J.R, Siligardi, G, Das, P, Morton, C.J, Rossi, C, Waterfield, M.D, Campbell, I.D, Ladbury, J.E. 登録日 1997-12-05 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase. Biochemistry, 35, 1996
5I11	Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, ... 著者 Camara-Artigas, A. 登録日 2016-02-05 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of the intertwined form of the Src tyrosine kinase SH3 domain T114S-Q128R mutant To Be Published
1BBZ	CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS 分子名称: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION 著者 Pisabarro, M.T, Serrano, L, Wilmanns, M. 登録日 1998-04-28 公開日 1998-11-25 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions. J.Mol.Biol., 281, 1998
5IHK	Crystal Structure of the alpha spectrin SH3 domain mutant N47A 分子名称: ACETATE ION, PROLINE, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2016-02-29 公開日 2017-03-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Crystal Structure of the alpha spectrin SH3 domain mutant N47A to be published
2RQV	Solution structure of SH3CI domain of Bem1p 分子名称: Bud emergence protein 1 著者 Takaku, T, Ogura, K, Inagaki, F. 登録日 2009-12-21 公開日 2010-04-21 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42 J.Biol.Chem., 285, 2010
2RQW	Solution structure of Bem1p SH3CI domain complexed with Ste20p-PRR peptide 分子名称: 24-meric peptide from Serine/threonine-protein kinase STE20, Bud emergence protein 1 著者 Takaku, T, Ogura, K, Inagaki, F. 登録日 2009-12-21 公開日 2010-04-21 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of a novel Cdc42-binding module of Bem1 and its interaction with Ste20 and Cdc42 J.Biol.Chem., 285, 2010
2ROT	Structure of chimeric variant of SH3 domain- SHH 分子名称: Spectrin alpha chain, brain 著者 Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. 登録日 2008-04-10 公開日 2009-04-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs". Biochim.Biophys.Acta, 1794, 2009
2RN8	NMR structure note: murine Itk SH3 domain 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Severin, A.J. 登録日 2007-12-08 公開日 2007-12-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure note: murine Itk SH3 domain To be Published
2V1R	Yeast Pex13 SH3 domain complexed with a peptide from Pex14 at 2.1 A resolution 分子名称: PEROXISOMAL MEMBRANE PROTEIN PAS20, PEX14 著者 Kursula, I, Kursula, P, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. 登録日 2007-05-29 公開日 2008-06-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Genomics of Yeast SH3 Domains To be Published
2RNA	Itk SH3 average minimized 分子名称: Tyrosine-protein kinase ITK/TSK 著者 Severin, A.J. 登録日 2007-12-08 公開日 2007-12-25 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 NMR structure note: murine Itk SH3 domain To be Published
2RMO	Solution structure of alpha-spectrin_SH3-bergerac from Chicken 分子名称: Spectrin alpha chain, brain 著者 Kutyshenko, V.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Fedyukina, D.V, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V. 登録日 2007-11-07 公開日 2008-09-30 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Study of the structure and dynamics of a chimeric variant of the SH3 domain (SHA-Bergerac) by NMR spectroscopy Russ.J.Bioorganic Chem., 34, 2008
2V1Q	Atomic-resolution structure of the yeast Sla1 SH3 domain 3 分子名称: CHLORIDE ION, CYTOSKELETON ASSEMBLY CONTROL PROTEIN SLA1, PLATINUM (II) ION, ... 著者 Kursula, I, Kursula, P, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M. 登録日 2007-05-29 公開日 2008-06-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Structural Genomics of Yeast SH3 Domains To be Published
2VKN	YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2 分子名称: MAP KINASE KINASE PBS2, PROTEIN SSU81, SULFATE ION 著者 Kursula, P, Kursula, I, Song, Y.H, Paraskevopoulos, K, Wilmanns, M. 登録日 2007-12-20 公開日 2008-02-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Genomics of Yeast SH3 Domains To be Published
2RPN	A crucial role for high intrinsic specificity in the function of yeast SH3 domains 分子名称: Actin-binding protein, Actin-regulating kinase 1 著者 Stollar, E.J, Garcia, B, Chong, A, Forman-Kay, J, Davidson, A. 登録日 2008-06-12 公開日 2009-06-16 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structural, functional, and bioinformatic studies demonstrate the crucial role of an extended peptide binding site for the SH3 domain of yeast Abp1p J.Biol.Chem., 284, 2009
2SEM	SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR 分子名称: PROTEIN (SEX MUSCLE ABNORMAL PROTEIN 5), PROTEIN (SH3 PEPTOID INHIBITOR) 著者 Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. 登録日 1998-11-02 公開日 1999-01-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
3UA7	Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein 分子名称: CHLORIDE ION, FORMIC ACID, GLYCEROL, ... 著者 Martin-Garcia, J.M, Ruiz-Sanz, J, Luque, I, Camara-Artigas, A. 登録日 2011-10-21 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein. Acta Crystallogr.,Sect.D, 68, 2012
5OB1	Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src 著者 Camara-Artigas, A. 登録日 2017-06-25 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.172 Å) 主引用文献 Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12 to be published
5OB0	Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 分子名称: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION 著者 Camara-Artigas, A. 登録日 2017-06-25 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.172 Å) 主引用文献 Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12 to be published
3SEM	SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR 分子名称: SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR 著者 Nguyen, J.T, Turck, C.W, Cohen, F.E, Zuckermann, R.N, Lim, W.A. 登録日 1998-11-02 公開日 1999-01-06 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science, 282, 1998
5QU8	Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV 分子名称: Cytoplasmic protein NCK1, SODIUM ION 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (0.93 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU3	Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QUA	Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221 分子名称: Cytoplasmic protein NCK1 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU1	Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A 分子名称: Cytoplasmic protein NCK1, SULFATE ION 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU5	Domain Swap in the first SH3 domain of human Nck1 分子名称: Cytoplasmic protein NCK1 著者 Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020
5QU2	Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY 分子名称: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION 著者 Rudolph, M.G. 登録日 2019-12-13 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain. J.Biol.Chem., 295, 2020

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