PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

---

7MK2	CryoEM Structure of NPR1 分子名称: Regulatory protein NPR1, ZINC ION 著者 Kumar, S, Zhou, Y, Dillard, L, Borgnia, M, Bartesaghi, A, Zhou, P. 登録日 2021-04-21 公開日 2022-03-16 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
7MK3	Crystal structure of NPR1 分子名称: CHLORIDE ION, GLYCEROL, Regulatory protein NPR1, ... 著者 Cheng, J, Wu, Q, Zhou, P. 登録日 2021-04-21 公開日 2022-03-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
7OH1	Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1 分子名称: FAB TT110, Tetanus toxin 著者 Grinzato, A, Kandiah, E, Zanotti, G. 登録日 2021-05-07 公開日 2021-10-27 最終更新日 2021-11-24 実験手法 ELECTRON MICROSCOPY (8 Å) 主引用文献 Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. J.Clin.Invest., 131, 2021
7OH0	Tetanus neurotoxin HC domain in complex with TT104-Fab1 分子名称: Fab TT104, Tetanus toxin 著者 Grinzato, A, Kandiah, E, Zanotti, G. 登録日 2021-05-07 公開日 2021-10-27 最終更新日 2021-11-24 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. J.Clin.Invest., 131, 2021
4IPS	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3,6-bis(4-hydroxybenzyl)piperazin-2-one, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, LeDu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IPW	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(3,4-dihydroxybenzyl)-6-(4-hydroxybenzyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-10 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
4IQ7	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-methylpiperazine-2,5-dione, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
7NM3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-135 分子名称: 14-3-3 protein sigma, 4-[4-(dimethylamino)piperidin-1-yl]sulfonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NK5	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-124 分子名称: 1-(4-methylphenyl)sulfonyl-4-(2-methylpropyl)piperazine, 14-3-3 protein sigma, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-17 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
3R1A	Closed crystal structure of cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene 分子名称: (4-tert-butylphenyl)acetaldehyde, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE 著者 Gay, S.C, Zhang, H, Stout, C.D, Hollenberg, P.F, Halpert, J.R. 登録日 2011-03-09 公開日 2011-05-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural Analysis of Mammalian Cytochrome P450 2B4 Covalently Bound to the Mechanism-Based Inactivator tert-Butylphenylacetylene: Insight into Partial Enzymatic Activity. Biochemistry, 50, 2011
7NM1	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-126 分子名称: 14-3-3 protein sigma, 4-(4-pyrrolidin-1-ylpiperidin-1-yl)sulfonylbenzaldehyde, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NLE	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-118 分子名称: 14-3-3 protein sigma, 4-(4-methylpiperazin-1-yl)sulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NLA	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-119 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-22 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
4IQ9	Substrate and reaction specificity of Mycobacterium tuberculosis cytochrome P450 CYP121 分子名称: (3S,6S)-3-(4-hydroxybenzyl)-6-(1H-indol-3-ylmethyl)piperazine-2,5-dione, Cytochrome P450 121, GLYCEROL, ... 著者 Fonvielle, M, Ledu, M.H, Lequin, O, Lecoq, A, Jacquet, M, Thai, R, Dubois, S, Grach, G, Gondry, M, Belin, P. 登録日 2013-01-11 公開日 2013-05-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Substrate and Reaction Specificity of Mycobacterium tuberculosis Cytochrome P450 CYP121: INSIGHTS FROM BIOCHEMICAL STUDIES AND CRYSTAL STRUCTURES. J.Biol.Chem., 288, 2013
7NM9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-110 分子名称: 14-3-3 protein sigma, 6-(2-bromanylimidazol-1-yl)pyridine-3-carbaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-23 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NJ9	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-133 分子名称: 14-3-3 protein sigma, 4-(3,4-dihydro-2~{H}-quinolin-1-ylsulfonyl)benzaldehyde, DI(HYDROXYETHYL)ETHER, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NJB	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-132 分子名称: 14-3-3 protein sigma, 4-piperidin-1-ylsulfonylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-16 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NK3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-128 分子名称: 14-3-3 protein sigma, 2-(4-methylphenyl)sulfonyl-3,4-dihydro-1~{H}-isoquinoline, CALCIUM ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2021-02-17 公開日 2021-06-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 An Exploration of Chemical Properties Required for Cooperative Stabilization of the 14-3-3 Interaction with NF-kappa B-Utilizing a Reversible Covalent Tethering Approach. J.Med.Chem., 64, 2021
7NQP	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound LvD1009 分子名称: 14-3-3 protein sigma, 2-bromanyl-4-(2-phenylimidazol-1-yl)benzaldehyde, MAGNESIUM ION, ... 著者 Wolter, M, Dijck, L.v, Cossar, P.J, Ottmann, C. 登録日 2021-03-02 公開日 2021-06-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 Reversible Covalent Imine-Tethering for Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc., 143, 2021
3R6W	paAzoR1 binding to nitrofurazone 分子名称: FLAVIN MONONUCLEOTIDE, FMN-dependent NADH-azoreductase 1, GLYCEROL, ... 著者 Ryan, A, Kaplan, K, Laurieri, N, Lowe, E, Sim, E. 登録日 2011-03-22 公開日 2011-08-24 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.085 Å) 主引用文献 Activation of nitrofurazone by azoreductases: multiple activities in one enzyme. Sci Rep, 1, 2011
4H8N	Crystal structure of conjugated polyketone reductase C2 from candida parapsilosis complexed with NADPH 分子名称: Conjugated polyketone reductase C2, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Qin, H.-M, Yamamura, A, Miyakawa, T, Maruoka, S, Ohtsuka, J, Nagata, K, Kataoka, M, Shimizu, S, Tanokura, M. 登録日 2012-09-23 公開日 2013-08-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of conjugated polyketone reductase from Candida parapsilosis IFO 0708 reveals conformational changes for substrate recognition upon NADPH binding Appl.Microbiol.Biotechnol., 98, 2014
3S7S	Crystal structure of human placental aromatase complexed with breast cancer drug exemestane 分子名称: (8alpha,10alpha,13alpha)-6-methylideneandrosta-1,4-diene-3,17-dione, Cytochrome P450 19A1, PROTOPORPHYRIN IX CONTAINING FE 著者 Ghosh, D. 登録日 2011-05-26 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Novel aromatase inhibitors by structure-guided design. J.Med.Chem., 55, 2012
3NC5	CYP134A1 structure with an open substrate binding loop 分子名称: Cytochrome P450 cypX, GLYCEROL, MAGNESIUM ION, ... 著者 Cryle, M.J, Schlichting, I. 登録日 2010-06-04 公開日 2010-08-11 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase. Biochemistry, 49, 2010
3NH5	Crystal structure of E177A-mutant murine aminoacylase 3 分子名称: ACETATE ION, Aspartoacylase-2, CHLORIDE ION, ... 著者 Hsieh, J.M, Tsirulnikov, K, Sawaya, M.R, Magilnick, N, Abuladze, N, Kurtz, I, Abramson, J, Pushkin, A. 登録日 2010-06-14 公開日 2010-10-20 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.094 Å) 主引用文献 Structures of aminoacylase 3 in complex with acetylated substrates. Proc.Natl.Acad.Sci.USA, 107, 2010
7OCK	MAT in complex with SAMH 分子名称: S-adenosylmethionine synthase, SAM hydrolase 著者 Simon, H, Kleiner, D, Shmulevich, F, Zarivach, R, Zalk, R, Tang, H, Ding, F, Bershtein, S. 登録日 2021-04-27 公開日 2021-07-21 最終更新日 2021-10-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 SAMase of Bacteriophage T3 Inactivates Escherichia coli's Methionine S -Adenosyltransferase by Forming Heteropolymers. Mbio, 12, 2021

<591592593594595596597598599600601602603604605606>