7T71
| Crystal Structure of Mevalonate 3,5-Bisphosphate Decarboxylase from Picrophilus Torridus | 分子名称: | Mevalonate 3,5-bisphosphate decarboxylase, OLEIC ACID | 著者 | Vinokur, J.M, Sawaya, M.R, Cascio, D, Collazo, M, Bowie, J.U. | 登録日 | 2021-12-14 | 公開日 | 2021-12-22 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | Crystal structure of mevalonate 3,5-bisphosphate decarboxylase reveals insight into the evolution of decarboxylases in the mevalonate metabolic pathways. J.Biol.Chem., 298, 2022
|
|
7SPO
| |
7TE8
| CA14-CBD-DB21 ternary complex | 分子名称: | CA14, DB21, cannabidiol | 著者 | Cao, S, Zheng, N. | 登録日 | 2022-01-04 | 公開日 | 2022-01-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Defining molecular glues with a dual-nanobody cannabidiol sensor. Nat Commun, 13, 2022
|
|
5B1H
| |
7TBG
| AtTPC1 D454N with 1 mM Ca2+ | 分子名称: | CALCIUM ION, SODIUM ION, Two pore calcium channel protein 1 | 著者 | Dickinson, M.S, Stroud, R.M. | 登録日 | 2021-12-22 | 公開日 | 2022-02-02 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Molecular basis of multistep voltage activation in plant two-pore channel 1. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7TDF
| |
7SP3
| E. coli RppH bound to Ap4A | 分子名称: | BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CHLORIDE ION, FLUORIDE ION, ... | 著者 | Serganov, A.A, Vasilyev, N, Nuthanakanti, A. | 登録日 | 2021-11-02 | 公開日 | 2022-03-09 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A distinct RNA recognition mechanism governs Np 4 decapping by RppH. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7SO6
| Crystal Structure of HIV-1 K103N, Y181C mutant Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-7-fluoro-2-naphthonitrile (JLJ635), a Non-nucleoside Inhibitor | 分子名称: | 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... | 著者 | Bertoletti, N, Frey, K.M, Anderson, K.S, Cisneros Trigo, J.A, Jorgensen, W.L, Chan, A.H. | 登録日 | 2021-10-29 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Front Mol Biosci, 9, 2022
|
|
7SO4
| Crystal Structure of HIV-1 Y181C mutant Reverse Transcriptase in Complex with 5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)-7-fluoro-2-naphthonitrile (JLJ635), a Non-nucleoside Inhibitor | 分子名称: | 5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}-7-fluoronaphthalene-2-carbonitrile, Reverse transcriptase/ribonuclease H, SULFATE ION, ... | 著者 | Bertoletti, N, Anderson, K.S, Cisneros Trigo, J.A, Jorgensen, W.L, Frey, K.M, Chan, A.H. | 登録日 | 2021-10-29 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase. Front Mol Biosci, 9, 2022
|
|
7T7T
| |
7SYA
| Kinetically trapped Pseudomonas-phage PaP3 portal protein - Full Length | 分子名称: | Portal protein | 著者 | Hou, C.F.D, Swanson, N.A, Li, F, Yang, R, Lokareddy, R.K, Cingolani, G. | 登録日 | 2021-11-24 | 公開日 | 2022-04-20 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J.Mol.Biol., 434, 2022
|
|
7T6M
| Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1 | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
|
|
7T6J
| |
7T6K
| |
7T7A
| Crystal Structure of Human SHOC2: A Leucine-Rich Repeat Protein | 分子名称: | Leucine-rich repeat protein SHOC-2, MAGNESIUM ION, NITRATE ION | 著者 | Hajian, B, Lemke, C, Kwon, J, Bian, Y, Fuller, C, Aguirre, J. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Nature, 609, 2022
|
|
7T6R
| |
5B1I
| |
7T6Q
| Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y. | 登録日 | 2021-12-14 | 公開日 | 2022-05-04 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis of TRPV5 regulation by physiological and pathophysiological modulators. Cell Rep, 39, 2022
|
|
7T6P
| |
7T6L
| |
7T6O
| |
7T6N
| |
7T7N
| Structure of SPCC1393.13 protein from fission yeast | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Damage-control phosphatase SPCC1393.13, PHOSPHATE ION | 著者 | Jacewicz, A, Sanchez, A.M, Shuman, S. | 登録日 | 2021-12-15 | 公開日 | 2022-06-01 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate. J.Biol.Chem., 298, 2022
|
|
7T7O
| |
7T7K
| Structure of SPAC806.04c protein from fission yeast bound to Co2+ | 分子名称: | CHLORIDE ION, COBALT (II) ION, Damage-control phosphatase SPAC806.04c, ... | 著者 | Jacewicz, A, Sanchez, A.M, Shuman, S. | 登録日 | 2021-12-15 | 公開日 | 2022-06-01 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate. J.Biol.Chem., 298, 2022
|
|