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1MTY
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METHANE MONOOXYGENASE HYDROXYLASE FROM METHYLOCOCCUS CAPSULATUS (BATH)
分子名称: FE (III) ION, METHANE MONOOXYGENASE HYDROXYLASE
著者Rosenzweig, A.C, Nordlund, P, Lippard, S.J, Frederick, C.A.
登録日1996-07-10
公開日1997-04-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactions.
Proteins, 29, 1997
1TUM
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MUTT PYROPHOSPHOHYDROLASE-METAL-NUCLEOTIDE-METAL COMPLEX, NMR, 16 STRUCTURES
分子名称: COBALT TETRAAMMINE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ...
著者Lin, J, Abeygunawardana, C, Frick, D.N, Bessman, M.J, Mildvan, A.S.
登録日1996-12-05
公開日1997-05-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the quaternary MutT-M2+-AMPCPP-M2+ complex and mechanism of its pyrophosphohydrolase action.
Biochemistry, 36, 1997
2EXL
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GRP94 N-terminal Domain bound to geldanamycin
分子名称: Endoplasmin, GELDANAMYCIN, PENTAETHYLENE GLYCOL, ...
著者Reardon, P.N, Immormino, R.M, Gewirth, D.T.
登録日2005-11-08
公開日2006-10-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
2GJA
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Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and NH4+
分子名称: AMMONIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Scrima, A, Wittinghofer, A.
登録日2006-03-30
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.
Embo J., 25, 2006
1LQ9
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Crystal Structure of a Monooxygenase from the Gene ActVA-Orf6 of Streptomyces coelicolor Strain A3(2)
分子名称: ACTVA-ORF6 MONOOXYGENASE, TETRAETHYLENE GLYCOL
著者Sciara, G, Kendrew, S.G, Miele, A.E, Marsh, N.G, Federici, L, Malatesta, F, Schimperna, G, Savino, C, Vallone, B.
登録日2002-05-09
公開日2003-01-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The structure of ActVA-Orf6, a novel type of monooxygenase involved in actinorhodin biosynthesis
EMBO J., 22, 2003
2GTP
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BU of 2gtp by Molmil
Crystal structure of the heterodimeric complex of human RGS1 and activated Gi alpha 1
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Soundararajan, M, Turnbull, A.P, Ugochukwu, E, Gorrec, F, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2006-04-28
公開日2006-05-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2GVZ
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Crystal Structure of Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with MANT-ATP and Mn
分子名称: 3'-O-[2-(METHYLAMINO)BENZOYL]ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE), 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Adenylate cyclase type 2, ...
著者Mou, T.-C, Sprang, S.R.
登録日2006-05-03
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.27 Å)
主引用文献Broad specificity of Mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors.
Mol.Pharmacol., 70, 2006
1Q68
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Solution structure of T-cell surface glycoprotein CD4 and Proto-oncogene tyrosine-protein kinase LCK fragments
分子名称: Proto-oncogene tyrosine-protein kinase LCK, T-cell surface glycoprotein CD4, ZINC ION
著者Kim, P.W, Sun, Z.Y, Blacklow, S.C, Wagner, G, Eck, M.J.
登録日2003-08-12
公開日2003-11-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A zinc clasp structure tethers Lck to T cell coreceptors CD4 and CD8.
Science, 301, 2003
2ESA
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BU of 2esa by Molmil
GRP94 n-terminal domain bound to geldanamycin: effects of mutants 168-169 KS-AA
分子名称: Endoplasmin, GELDANAMYCIN, TETRAETHYLENE GLYCOL, ...
著者Immormino, R.M, Metzger IV, L.E, Gewirth, D.T.
登録日2005-10-25
公開日2006-10-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of GRP94 with the specific mutation KS168-169AA; with bound Geldanamycin
To be Published
2GJ9
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Structure of the MnmE G-domain in complex with GDP*AlF4-, Mg2+ and Rb+
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RUBIDIUM ION, ...
著者Scrima, A, Wittinghofer, A.
登録日2006-03-30
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dimerisation-dependent GTPase reaction of MnmE: how potassium acts as GTPase-activating element.
Embo J., 25, 2006
1J07
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BU of 1j07 by Molmil
Crystal structure of the mouse acetylcholinesterase-decidium complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,8-DIAMINO-5,10'-(TRIMETHYLAMMONIUM)DECYL-6-PHENYL PHENANTHRIDINIUM, CARBONATE ION, ...
著者Bourne, Y, Taylor, P, Radic, Z, Marchot, P.
登録日2002-11-07
公開日2003-02-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
EMBO J., 22, 2003
1T5T
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BU of 1t5t by Molmil
Structure of the (SR)Ca2+-ATPase Ca2-E1-ADP:AlF4- form
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ...
著者Sorensen, T.L.-M, Moller, J.V, Nissen, P.
登録日2004-05-05
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Phosphoryl transfer and calcium ion occlusion in the calcium pump.
Science, 304, 2004
1T6B
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Crystal structure of B. anthracis Protective Antigen complexed with human Anthrax toxin receptor
分子名称: Anthrax toxin receptor 2, CALCIUM ION, MANGANESE (II) ION, ...
著者Santelli, E, Bankston, L.A, Leppla, S.H, Liddington, R.C.
登録日2004-05-05
公開日2004-07-20
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of a complex between anthrax toxin and its host cell receptor
Nature, 430, 2004
1TAD
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BU of 1tad by Molmil
GTPASE MECHANISM OF GPROTEINS FROM THE 1.7-ANGSTROM CRYSTAL STRUCTURE OF TRANSDUCIN ALPHA-GDP-ALF4-
分子名称: CACODYLATE ION, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ...
著者Sondek, J, Lambright, D.G, Noel, J.P, Hamm, H.E, Sigler, P.B.
登録日1995-01-05
公開日1995-05-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献GTPase mechanism of Gproteins from the 1.7-A crystal structure of transducin alpha-GDP-AIF-4.
Nature, 372, 1994
1W6J
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BU of 1w6j by Molmil
Structure of human OSC in complex with Ro 48-8071
分子名称: LANOSTEROL SYNTHASE, TETRADECANE, [4-({6-[ALLYL(METHYL)AMINO]HEXYL}OXY)-2-FLUOROPHENYL](4-BROMOPHENYL)METHANONE, ...
著者Thoma, R, Schulz-Gasch, T, D'Arcy, B, Benz, J, Aebi, J, Dehmlow, H, Hennig, M, Ruf, A.
登録日2004-08-18
公開日2004-10-29
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Insight Into Steroid Scaffold Formation from the Structure of Human Oxidosqualene Cyclase
Nature, 432, 2004
1VG0
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BU of 1vg0 by Molmil
The crystal structures of the REP-1 protein in complex with monoprenylated Rab7 protein
分子名称: CHLORIDE ION, GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Rak, A, Pylypenko, O, Niculae, A, Pyatkov, K, Goody, R.S, Alexandrov, K.
登録日2004-04-22
公開日2004-07-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the Rab7:REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease
Cell(Cambridge,Mass.), 117, 2004
1SVK
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BU of 1svk by Molmil
Structure of the K180P mutant of Gi alpha subunit bound to AlF4 and GDP
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i), alpha-1 subunit, ...
著者Thomas, C.J, Du, X, Li, P, Wang, Y, Ross, E.M, Sprang, S.R.
登録日2004-03-29
公開日2004-06-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein {alpha}-subunit.
Proc.Natl.Acad.Sci.USA, 101, 2004
1QF9
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BU of 1qf9 by Molmil
PH INFLUENCES FLUORIDE COORDINATION NUMBER OF THE ALFX PHOSPHORYL TRANSFER TRANSITION STATE ANALOG IN UMP/CMP KINASE
分子名称: ADENOSINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ...
著者Schlichting, I, Reinstein, J.
登録日1999-04-07
公開日1999-08-16
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献pH influences fluoride coordination number of the AlFx phosphoryl transfer transition state analog.
Nat.Struct.Biol., 6, 1999
1QK8
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TRYPAREDOXIN-I FROM CRITHIDIA FASCICULATA
分子名称: TRYPAREDOXIN-I
著者Alphey, M.S, Hunter, W.N.
登録日1999-07-11
公開日2000-06-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The High Resolution Crystal Structure of Recombinant Crithidia Fasciculata Tryparedoxin-I
J.Biol.Chem., 274, 1999
2HW7
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Crystal Structure of Mnk2-D228G in complex with Staurosporine
分子名称: MAP kinase-interacting serine/threonine-protein kinase 2, STAUROSPORINE, ZINC ION
著者Jauch, R, Wahl, M.C.
登録日2006-08-01
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
2HW6
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Crystal structure of Mnk1 catalytic domain
分子名称: MAP kinase-interacting serine/threonine-protein kinase 1, SULFATE ION
著者Jauch, R, Wahl, M.C.
登録日2006-08-01
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.
Embo J., 25, 2006
1M3D
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Structure of Type IV Collagen NC1 Domains
分子名称: BROMIDE ION, GLYCEROL, LUTETIUM (III) ION, ...
著者Sundaramoorthy, M, Meiyappan, M, Todd, P, Hudson, B.G.
登録日2002-06-27
公開日2003-01-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of NC1 Domains. Structural Basis for Type IV Collagen Assembly in Basement Membranes
J.Biol.Chem., 277, 2002
2EZK
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BU of 2ezk by Molmil
SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, REGULARIZED MEAN STRUCTURE
分子名称: TRANSPOSASE
著者Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M.
登録日1997-10-04
公開日1998-01-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.
EMBO J., 16, 1997
2EZL
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SOLUTION NMR STRUCTURE OF THE IBETA SUBDOMAIN OF THE MU END DNA BINDING DOMAIN OF PHAGE MU TRANSPOSASE, 29 STRUCTURES
分子名称: TRANSPOSASE
著者Clore, G.M, Clubb, R.T, Schumaker, S, Gronenborn, A.M.
登録日1997-10-04
公開日1998-01-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the Mu end DNA-binding ibeta subdomain of phage Mu transposase: modular DNA recognition by two tethered domains.
EMBO J., 16, 1997
2DF3
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The structure of Siglec-7 in complex with alpha(2,3)/alpha(2,6) disialyl lactotetraosyl 2-(trimethylsilyl)ethyl
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-[N-acetyl-alpha-neuraminic acid-(2-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Attrill, H.
登録日2006-02-23
公開日2006-06-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structure of siglec-7 in complex with sialosides: leads for rational structure-based inhibitor design
Biochem.J., 397, 2006

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