PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3MHL	Crystal structure of human carbonic anhydrase isozyme II with 4-{[N-(6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide 分子名称: 4-{[(6-methoxy-5-nitropyrimidin-4-yl)amino]methyl}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Grazulis, S, Manakova, E, Golovenko, D. 登録日 2010-04-08 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 4-[N-(Substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII Bioorg.Med.Chem., 18, 2010
3MYX	Crystal structure of a PSPTO_0244 (Protein with unknown function which belongs to Pfam DUF861 family) from Pseudomonas syringae pv. tomato str. DC3000 at 1.30 A resolution 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, uncharacterized protein PSPTO_0244 著者 Joint Center for Structural Genomics (JCSG) 登録日 2010-05-11 公開日 2010-06-09 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of a PSPTO_0244 (Protein with unknown function which belongs to Pfam DUF861 family) from Pseudomonas syringae pv. tomato str. DC3000 at 1.30 A resolution To be published
3KTJ	Structure of ClpP in complex with ADEP2 in monoclinic crystal form 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ATP-dependent Clp protease proteolytic subunit, Acyldepsipeptide 2 著者 Lee, B.-G, Brotz-Oesterhelt, H, Song, H.K. 登録日 2009-11-25 公開日 2010-03-23 最終更新日 2012-12-12 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of ClpP in complex with acyldepsipeptide antibiotics reveal its activation mechanism Nat.Struct.Mol.Biol., 17, 2010
3KU4	Trapping of an oxocarbenium ion intermediate in UP crystals 分子名称: SULFATE ION, Uridine phosphorylase 著者 Paul, D, O'Leary, S, Rajashankar, K, Bu, W, Toms, A, Settembre, E, Sanders, J, Begley, T.P, Ealick, S.E. 登録日 2009-11-26 公開日 2010-04-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Glycal formation in crystals of uridine phosphorylase. Biochemistry, 49, 2010
3KGS	V30M mutant human transthyretin (TTR) (apoV30M) pH 7.5 分子名称: Transthyretin 著者 Trivella, D.B, Polikarpov, I. 登録日 2009-10-29 公開日 2010-03-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand-binding. J.Struct.Biol., 170, 2010
3KGY	Crystal structure of Putative dihydrofolate reductase (YP_001636057.1) from CHLOROFLEXUS AURANTIACUS J-10-FL at 1.50 A resolution 分子名称: 1,2-ETHANEDIOL, Bifunctional deaminase-reductase domain protein, CHLORIDE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-10-29 公開日 2009-11-24 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Putative dihydrofolate reductase (YP_001636057.1) from CHLOROFLEXUS AURANTIACUS J-10-FL at 1.50 A resolution To be published
3KH9	Crystal structure of the periplasmic soluble domain of oxidized CcmG from Pseudomonas aeruginosa 分子名称: Thiol:disulfide interchange protein dsbE 著者 Di Matteo, A, Calosci, N, Gianni, S, Jemth, P, Brunori, M, Travaglini Allocatelli, C. 登録日 2009-10-30 公開日 2010-04-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus. Proteins, 78, 2010
3KJG	ADP-bound state of CooC1 分子名称: ADENOSINE-5'-DIPHOSPHATE, CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC 著者 Jeoung, J.-H, Dobbek, H. 登録日 2009-11-03 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the ATP-Dependent Maturation Factor of Ni,Fe-Containing Carbon Monoxide Dehydrogenases J.Mol.Biol., 396, 2010
3KXF	Crystal Structure of SB27 TCR in complex with the 'restriction triad' mutant HLA-B*3508-13mer 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... 著者 Archbold, J.K, Tynan, F.E, Gras, S, Rossjohn, J. 登録日 2009-12-03 公開日 2010-06-09 最終更新日 2014-02-26 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Hard wiring of T cell receptor specificity for the major histocompatibility complex is underpinned by TCR adaptability Proc.Natl.Acad.Sci.USA, 107, 2010
3KKF	Crystal structure of Putative antibiotic biosynthesis monooxygenase (NP_810307.1) from Bacteriodes thetaiotaomicron VPI-5482 at 1.30 A resolution 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2009-11-05 公開日 2009-12-01 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of Putative antibiotic biosynthesis monooxygenase (NP_810307.1) from Bacteriodes thetaiotaomicron VPI-5482 at 1.30 A resolution To be published
3L0P	Crystal structures of Iron containing Adenylate kinase from Desulfovibrio gigas 分子名称: Adenylate kinase, FE (III) ION, GLYCEROL 著者 Mukhopadhyay, A, Trincao, J, Romao, M.J. 登録日 2009-12-10 公開日 2010-12-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the zinc-, cobalt-, and iron-containing adenylate kinase from Desulfovibrio gigas: a novel metal-containing adenylate kinase from Gram-negative bacteria J.Biol.Inorg.Chem., 16, 2011
3L16	Discovery of (thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer 分子名称: 5-(6-{[4-(methylsulfonyl)piperazin-1-yl]methyl}-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)pyridin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 著者 Murray, J.M, Wiesmann, C. 登録日 2009-12-10 公開日 2010-02-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Discovery of (Thienopyrimidin-2-yl)aminopyrimidines as Potent, Selective, and Orally Available Pan-PI3-Kinase and Dual Pan-PI3-Kinase/mTOR Inhibitors for the Treatment of Cancer. J.Med.Chem., 53, 2010
3KL9	Crystal structure of PepA from Streptococcus pneumoniae 分子名称: Glutamyl aminopeptidase, ZINC ION 著者 Kim, K.K, Lee, S, Kim, D. 登録日 2009-11-07 公開日 2010-02-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for the substrate specificity of PepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease Biochem.Biophys.Res.Commun., 391, 2010
3L1J	Crystal structure of EstE5, was soaked by ZnSO4 分子名称: Esterase/lipase 著者 Nam, K.H, Hwang, K.Y. 登録日 2009-12-11 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into the noninvasive inhibition of HSL-homolog EstE5 by organic solvents and metal ions To be Published
3L1S	3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3 分子名称: (4E)-4-[(4-chlorophenyl)hydrazono]-5-(3,4-dimethoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one, Glycogen synthase kinase-3 beta, PHOSPHATE ION 著者 Haar, T.E. 登録日 2009-12-14 公開日 2010-03-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3beta. Bioorg.Med.Chem.Lett., 20, 2010
3L2W	Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with manganese and GS9137 (Elvitegravir) 分子名称: 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*TP*GP*TP*A)-3', 5'-D(*TP*AP*CP*AP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', 6-(3-chloro-2-fluorobenzyl)-1-[(1S)-1-(hydroxymethyl)-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... 著者 Hare, S, Gupta, S.S, Cherepanov, P. 登録日 2009-12-15 公開日 2010-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Retroviral intasome assembly and inhibition of DNA strand transfer Nature, 464, 2010
3KN8	Crystal Structure of Haemophilus influenzae Y196A mutant Holo Ferric ion-Binding Protein A 分子名称: FE (III) ION, Iron-utilization periplasmic protein, PHOSPHATE ION 著者 Shouldice, S.R, Schryvers, A.B. 登録日 2009-11-12 公開日 2010-09-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The role of vicinal tyrosine residues in the function of Haemophilus influenzae ferric binding protein A. Biochem.J., 2010
3L3T	Human mesotrypsin complexed with amyloid precursor protein inhibitor variant (APPIR15K) 分子名称: CALCIUM ION, FORMIC ACID, PRSS3 protein, ... 著者 Salameh, M.A, Soares, A.S, Radisky, E.S. 登録日 2009-12-17 公開日 2010-09-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.378 Å) 主引用文献 Determinants of affinity and proteolytic stability in interactions of Kunitz family protease inhibitors with mesotrypsin. J.Biol.Chem., 285, 2010
3KO4	Crystal structure of D-Tyr-tRNA(Tyr) deacylase from Plasmodium falciparum in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KOC	DTD from Plasmodium falciparum in complex with D-Histidine 分子名称: D-HISTIDINE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3L51	Crystal Structure of the Mouse Condensin Hinge Domain 分子名称: GLYCEROL, Structural maintenance of chromosomes protein 2, Structural maintenance of chromosomes protein 4 著者 Griese, J.J, Hopfner, K.-P. 登録日 2009-12-21 公開日 2010-02-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.506 Å) 主引用文献 Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins Nucleic Acids Res., 38, 2010
3KEB	Thiol peroxidase from Chromobacterium violaceum 分子名称: CHLORIDE ION, Probable thiol peroxidase, SULFATE ION 著者 Osipiuk, J, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2009-10-25 公開日 2009-11-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 X-ray crystal structure of thiol peroxidase from Chromobacterium violaceum To be Published
3KEP	Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae 分子名称: 1,2-ETHANEDIOL, Nucleoporin NUP145 著者 Sampathkumar, P, Ozyurt, S.A, Do, J, Bain, K, Dickey, M, Gheyi, T, Sali, A, Kim, S.J, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Rout, M, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-10-26 公開日 2009-12-22 最終更新日 2021-02-10 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145. Proteins, 78, 2010
3KQV	Crystal Structure of hPNMT in Complex AdoHcy and Formanilide 分子名称: FORMANILIDE, Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Drinkwater, N, Martin, J.L. 登録日 2009-11-17 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment-based screening by X-ray crystallography, MS and isothermal titration calorimetry to identify PNMT (phenylethanolamine N-methyltransferase) inhibitors. Biochem.J., 431, 2010
3KG9	Dehydratase domain from CurK module of Curacin polyketide synthase 分子名称: CurK 著者 Akey, D.L, Smith, J.L. 登録日 2009-10-28 公開日 2010-01-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structures of Dehydratase Domains from the Curacin Polyketide Biosynthetic Pathway. Structure, 18, 2010

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