5B4O
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![BU of 5b4o by Molmil](/molmil-images/mine/5b4o) | Crystal structure of Macrophage Migration Inhibitory Factor in complex with BTZO-14 | 分子名称: | 1,2-ETHANEDIOL, 2-pyridin-3-yl-1,3-benzothiazin-4-one, Macrophage migration inhibitory factor, ... | 著者 | Oki, H, Igaki, S, Moriya, Y, Hayano, Y, Habuka, N. | 登録日 | 2016-04-07 | 公開日 | 2016-04-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expression Chem. Biol., 17, 2010
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5URD
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![BU of 5urd by Molmil](/molmil-images/mine/5urd) | wild type rat CYPOR bound with NADP+ - oxidized form | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Kim, J.J. | 登録日 | 2017-02-10 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. Biochemistry, 57, 2018
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5URH
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![BU of 5urh by Molmil](/molmil-images/mine/5urh) | CYPOR/D632A with NADP+ | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Kim, J.J. | 登録日 | 2017-02-10 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. Biochemistry, 57, 2018
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5AAA
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![BU of 5aaa by Molmil](/molmil-images/mine/5aaa) | Structure of L1198F Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib | 分子名称: | 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine, ALK TYROSINE KINASE RECEPTOR | 著者 | McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. | 登録日 | 2015-07-23 | 公開日 | 2016-06-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F. N.Engl.J.Med., 374, 2016
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5VBN
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![BU of 5vbn by Molmil](/molmil-images/mine/5vbn) | Crystal Structure of human DNA polymerase epsilon B-subunit in complex with C-terminal domain of catalytic subunit | 分子名称: | DNA polymerase epsilon catalytic subunit A, DNA polymerase epsilon subunit 2, SULFATE ION, ... | 著者 | Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H. | 登録日 | 2017-03-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the human Pol B-subunit in complex with the C-terminal domain of the catalytic subunit. J. Biol. Chem., 292, 2017
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8IAU
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![BU of 8iau by Molmil](/molmil-images/mine/8iau) | Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Nakashima, R, Taguchi, A. | 登録日 | 2023-02-09 | 公開日 | 2023-06-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Functional and structural characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance. J.Biol.Chem., 299, 2023
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5AZU
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![BU of 5azu by Molmil](/molmil-images/mine/5azu) | |
6H0Q
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![BU of 6h0q by Molmil](/molmil-images/mine/6h0q) | B1-type ACP domain from module 7 of MLSB | 分子名称: | Type I modular polyketide synthase | 著者 | Moretto, L, Heylen, R, Holroyd, N, Vance, S, Broadhurst, R.W. | 登録日 | 2018-07-10 | 公開日 | 2019-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold. Sci Rep, 9, 2019
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4QPI
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![BU of 4qpi by Molmil](/molmil-images/mine/4qpi) | Crystal structure of hepatitis A virus | 分子名称: | CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2014-06-23 | 公開日 | 2014-10-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | 主引用文献 | Hepatitis A virus and the origins of picornaviruses. Nature, 517, 2015
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6HBW
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![BU of 6hbw by Molmil](/molmil-images/mine/6hbw) | |
5BIR
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![BU of 5bir by Molmil](/molmil-images/mine/5bir) | |
5BJ4
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![BU of 5bj4 by Molmil](/molmil-images/mine/5bj4) | THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 | 分子名称: | PHOSPHATE ION, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE | 著者 | Ura, H, Nakai, T, Kawaguchi, S.I, Miyahara, I, Hirotsu, K, Kuramitsu, S. | 登録日 | 1999-01-11 | 公開日 | 2003-09-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Substrate recognition mechanism of thermophilic dual-substrate enzyme J.BIOCHEM.(TOKYO), 130, 2001
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5ZEA
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![BU of 5zea by Molmil](/molmil-images/mine/5zea) | Crystal structure of the nucleotide-free mutant A3B3 | 分子名称: | GLYCEROL, V-type sodium ATPase catalytic subunit A, V-type sodium ATPase subunit B | 著者 | Maruyama, S, Suzuki, K, Mizutani, K, Saito, Y, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Ichiro, Y, Murata, T. | 登録日 | 2018-02-27 | 公開日 | 2019-02-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.384 Å) | 主引用文献 | Metastable asymmetrical structure of a shaftless V1motor. Sci Adv, 5, 2019
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5CVZ
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5URE
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![BU of 5ure by Molmil](/molmil-images/mine/5ure) | Wild type rat CYPOR bound with NADP+ - reduced form | 分子名称: | FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Xia, C, Kim, J.J. | 登録日 | 2017-02-10 | 公開日 | 2018-02-14 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer. Biochemistry, 57, 2018
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5AZF
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![BU of 5azf by Molmil](/molmil-images/mine/5azf) | Crystal structure of LGG-1 complexed with a WEEL peptide | 分子名称: | CADMIUM ION, Protein lgg-1, SULFATE ION, ... | 著者 | Watanabe, Y, Noda, N.N. | 登録日 | 2015-10-05 | 公開日 | 2015-12-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy. Mol.Cell, 60, 2015
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5AOO
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![BU of 5aoo by Molmil](/molmil-images/mine/5aoo) | X-ray structure of a human Kobuvirus: Aichi virus A (AiV) | 分子名称: | VP0, VP1, VP3 | 著者 | Sabin, C, Palkova, L, Plevka, P. | 登録日 | 2015-09-11 | 公開日 | 2016-03-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The Use of Noncrystallographic Symmetry Averaging to Solve Structures from Data Affected by Perfect Hemihedral Twinning Acta Crystallogr.,Sect.F, 72, 2016
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5V6G
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![BU of 5v6g by Molmil](/molmil-images/mine/5v6g) | Crystal structure of Influenza A virus Matrix Protein M1(NLS-88R) | 分子名称: | Matrix protein 1 | 著者 | Musayev, F.N, Safo, M.K, Desai, U.R, Xie, H, Mosier, P.D, Chiang, M.-J. | 登録日 | 2017-03-16 | 公開日 | 2017-04-12 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Maintaining pH-dependent conformational flexibility of M1 is critical for efficient influenza A virus replication. Emerg Microbes Infect, 6, 2017
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5UPJ
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![BU of 5upj by Molmil](/molmil-images/mine/5upj) | HIV-2 PROTEASE/U99283 COMPLEX | 分子名称: | 5,6,7,8,9,10-HEXAHYDRO-4-HYDROXY-3-(1-PHENYLPROPYL)CYCLOOCTA[B]PYRAN-2-ONE, HIV-2 PROTEASE | 著者 | Watenpaugh, K.D, Mulichak, A.M, Finzel, B.C. | 登録日 | 1996-12-10 | 公開日 | 1997-04-21 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Use of medium-sized cycloalkyl rings to enhance secondary binding: discovery of a new class of human immunodeficiency virus (HIV) protease inhibitors. J.Med.Chem., 38, 1995
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5E0B
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![BU of 5e0b by Molmil](/molmil-images/mine/5e0b) | Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution | 分子名称: | GLYCEROL, L(+)-TARTARIC ACID, N-acetyl-beta-muramic acid, ... | 著者 | Sharma, P, Yamini, S, Dube, D, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2015-09-28 | 公開日 | 2015-10-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of the complex of Peptidoglycan recognition protein PGRP-S with N-Acetyl Muramic acid at 2.6 A resolution To Be Published
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5C2J
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![BU of 5c2j by Molmil](/molmil-images/mine/5c2j) | Complex structure of the GAP domain of MgcRacGAP and Cdc42 | 分子名称: | ALUMINUM FLUORIDE, Cell division control protein 42 homolog, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Murayama, K, Kato-Murayama, M, Hosaka, T, Kitamura, T, Yokoyama, S, Shirouzu, M. | 登録日 | 2015-06-16 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of G-protein target alternation of MgcRacGAP by phospholylation To Be Published
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5E96
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![BU of 5e96 by Molmil](/molmil-images/mine/5e96) | Crystal structure of aminoglycoside 6'-acetyltransferase type Ii | 分子名称: | 1,2-ETHANEDIOL, Aminoglycoside 6'-acetyltransferase, PHOSPHATE ION | 著者 | Berghuis, A.M, Burk, D.L, Baettig, O.M, Shi, K. | 登録日 | 2015-10-14 | 公開日 | 2016-07-06 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Comprehensive characterization of ligand-induced plasticity changes in a dimeric enzyme. Febs J., 283, 2016
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4KG9
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7PKR
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![BU of 7pkr by Molmil](/molmil-images/mine/7pkr) | Vault structure in primmed conformation | 分子名称: | Major vault protein | 著者 | Guerra, P, Gonzalez-Alamos, M, Llauro, A, Casanas, A, Querol-Audi, J, de Pablo, P, Verdaguer, N. | 登録日 | 2021-08-26 | 公開日 | 2022-03-16 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Symmetry disruption commits vault particles to disassembly. Sci Adv, 8, 2022
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4KRT
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![BU of 4krt by Molmil](/molmil-images/mine/4krt) | |