PDB: 3581 件ウェブページステータス検索Chemie searchBIRD

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4W51	T4 Lysozyme L99A with No Ligand Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W53	T4 Lysozyme L99A with Toluene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, TOLUENE 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W56	T4 Lysozyme L99A with sec-Butylbenzene Bound 分子名称: (2R)-butan-2-ylbenzene, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
4W59	T4 Lysozyme L99A with n-Hexylbenzene Bound 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Endolysin, hexylbenzene 著者 Merski, M, Shoichet, B.K, Eidam, O, Fischer, M. 登録日 2014-08-16 公開日 2015-04-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Homologous ligands accommodated by discrete conformations of a buried cavity. Proc.Natl.Acad.Sci.USA, 112, 2015
6FFH	Crystal Structure of mGluR5 in complex with Fenobam at 2.65 A 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-(3-chlorophenyl)-3-(3-methyl-5-oxidanylidene-4~{H}-imidazol-2-yl)urea, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... 著者 Christopher, J.A, Orgovan, Z, Congreve, M, Dore, A.S, Errey, J.C, Marshall, F.H, Mason, J.S, Okrasa, K, Rucktooa, P, Serrano-Vega, M.J, Ferenczy, G.G, Keseru, G.M. 登録日 2018-01-08 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures. J.Med.Chem., 62, 2019
6FFI	Crystal Structure of mGluR5 in complex with MMPEP at 2.2 A 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[2-(3-methoxyphenyl)ethynyl]-6-methyl-pyridine, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5, ... 著者 Christopher, J.A, Orgovan, Z, Congreve, M, Dore, A.S, Errey, J.C, Marshall, F.H, Mason, J.S, Okrasa, K, Rucktooa, P, Serrano-Vega, M.J, Ferenczy, G.G, Keseru, G.M. 登録日 2018-01-08 公開日 2018-03-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures. J.Med.Chem., 62, 2019
7P2L	thermostabilised 7TM domain of human mGlu5 receptor bound to photoswitchable ligand alloswitch-1 分子名称: 2-chloranyl-~{N}-[2-methoxy-4-[(~{E})-pyridin-2-yldiazenyl]phenyl]benzamide, Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5 著者 Huang, C.Y, Vinothkumar, K.R, Lebon, G. 登録日 2021-07-06 公開日 2021-09-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Agonists and allosteric modulators promote signaling from different metabotropic glutamate receptor 5 conformations. Cell Rep, 36, 2021
5TZY	GPR40 in complex with AgoPAM AP8 and partial agonist MK-8666 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S,3R)-3-cyclopropyl-3-[(2R)-2-(1-{(1S)-1-[5-fluoro-2-(trifluoromethoxy)phenyl]ethyl}piperidin-4-yl)-3,4-dihydro-2H-1-benzopyran-7-yl]-2-methylpropanoic acid, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, ... 著者 Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. 登録日 2016-11-22 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.22 Å) 主引用文献 Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nat. Struct. Mol. Biol., 24, 2017
5T04	STRUCTURE OF CONSTITUTIVELY ACTIVE NEUROTENSIN RECEPTOR 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, ARG-ARG-PRO-TYR-ILE-LEU, DI(HYDROXYETHYL)ETHER, ... 著者 Krumm, B, Botos, I, Grisshammer, R. 登録日 2016-08-15 公開日 2016-12-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and dynamics of a constitutively active neurotensin receptor. Sci Rep, 6, 2016
5TZR	GPR40 in complex with partial agonist MK-8666 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (5aR,6S,6aS)-3-({2',6'-dimethyl-4'-[3-(methylsulfonyl)propoxy][1,1'-biphenyl]-3-yl}methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid, Free fatty acid receptor 1,Endolysin,Free fatty acid receptor 1, ... 著者 Lu, J, Byrne, N, Patel, S, Sharma, S, Soisson, S.M. 登録日 2016-11-22 公開日 2017-06-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40. Nat. Struct. Mol. Biol., 24, 2017
5KIO	PSEUDO T4 LYSOZYME MUTANT - Y18PHE-I 分子名称: 2-HYDROXYETHYL DISULFIDE, Endolysin 著者 Scholfield, M.R. 登録日 2016-06-16 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structure-Energy Relationships of Halogen Bonds in Proteins. Biochemistry, 56, 2017
5EWX	Fusion protein of T4 lysozyme and B4 domain of protein A from staphylococcal aureus with chemical cross-linker EY-CBS 分子名称: 2,2'-ethyne-1,2-diylbis{5-[(chloroacetyl)amino]benzenesulfonic acid}, Endolysin,Immunoglobulin G-binding protein A,Endolysin 著者 Jeong, W.H, Lee, H, Song, D.H, Lee, J.O. 登録日 2015-11-22 公開日 2016-03-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Connecting two proteins using a fusion alpha helix stabilized by a chemical cross linker. Nat Commun, 7, 2016
5LWO	Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K 分子名称: 2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. 登録日 2016-09-18 公開日 2017-03-08 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.183 Å) 主引用文献 Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins. J Phys Chem Lett, 8, 2017
4YXA	Complex of SpaO(SPOA1,2 SeMet) and OrgB(APAR)::T4lysozyme fusion protein 分子名称: Oxygen-regulated invasion protein OrgB,Endolysin, Surface presentation of antigens protein SpaO 著者 Notti, R.Q, Stebbins, C.E. 登録日 2015-03-22 公開日 2015-06-03 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 A common assembly module in injectisome and flagellar type III secretion sorting platforms. Nat Commun, 6, 2015
5G27	Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at Room Temperature 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, ENDOLYSIN, ... 著者 Gohlke, U, Consentius, P, Loll, B, Mueller, R, Kaupp, M, Heinemann, U, Risse, T. 登録日 2016-04-07 公開日 2016-11-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-Ray Crystallography and Site-Directed Spin Labeling. J.Am.Chem.Soc., 138, 2016
8P3A	bacteriophage T5 l-alanoyl-d-glutamate peptidase Zn2+/Ca2+ form 分子名称: CALCIUM ION, L-alanyl-D-glutamate peptidase, ZINC ION 著者 Prokhorov, D.A, Kutyshenko, V.P, Mikoulinskaia, G.V. 登録日 2023-05-17 公開日 2023-07-05 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Mechanism of Ca2+-dependent activation of L-alanoyl-D-glutamate peptidase bacteriophage T5. To Be Published
7L3J	T4 Lysozyme L99A - benzylacetate - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3A	T4 Lysozyme L99A - toluene - cryo 分子名称: Endolysin, TOLUENE 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.11 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L39	T4 Lysozyme L99A - toluene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L38	T4 Lysozyme L99A - Apo - cryo 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L37	T4 Lysozyme L99A - Apo - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.439 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3B	T4 Lysozyme L99A - iodobenzene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3G	T4 Lysozyme L99A - 4-iodotoluene - cryo 分子名称: 1-iodo-4-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.27 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3H	T4 Lysozyme L99A - ethylbenzene - RT 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021
7L3F	T4 Lysozyme L99A - 4-iodotoluene - RT 分子名称: 1-iodo-4-methylbenzene, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Fischer, M, Bradford, S.Y.C. 登録日 2020-12-17 公開日 2021-10-27 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Temperature artifacts in protein structures bias ligand-binding predictions. Chem Sci, 12, 2021

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