6QPB
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![BU of 6qpb by Molmil](/molmil-images/mine/6qpb) | Cryo-EM structure of calcium-free mTMEM16F lipid scramblase in digitonin | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6 | 著者 | Alvadia, C, Lim, N.K, Clerico Mosina, V, Oostergetel, G.T, Dutzler, R, Paulino, C. | 登録日 | 2019-02-13 | 公開日 | 2019-03-06 | 最終更新日 | 2019-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F. Elife, 8, 2019
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3LY0
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![BU of 3ly0 by Molmil](/molmil-images/mine/3ly0) | Crystal structure of metallo peptidase from Rhodobacter sphaeroides liganded with phosphinate mimic of dipeptide L-Ala-D-Ala | 分子名称: | (2R)-3-[(R)-[(1R)-1-aminoethyl](hydroxy)phosphoryl]-2-methylpropanoic acid, Dipeptidase AC. Metallo peptidase. MEROPS family M19, ZINC ION | 著者 | Fedorov, A.A, Fedorov, E.V, Cummings, J, Raushel, F.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2010-02-25 | 公開日 | 2010-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Crystal structure of metallo peptidase from Rhodobacter sphaeroides
liganded with phosphinate mimic of dipeptide L-Ala-D-Ala To be Published
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9FFB
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![BU of 9ffb by Molmil](/molmil-images/mine/9ffb) | ss-dsDNA-FANCD2-FANCI complex | 分子名称: | DNA (5'-D(P*CP*GP*AP*TP*GP*TP*CP*TP*CP*TP*AP*GP*AP*CP*AP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*GP*CP*AP*GP*CP*TP*GP*TP*CP*TP*AP*GP*AP*GP*AP*CP*AP*TP*CP*GP*AP*T)-3'), Fanconi anemia complementation group I, ... | 著者 | Alcon, P, Passmore, L.A. | 登録日 | 2024-05-22 | 公開日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | 主引用文献 | ss-dsDNA-FANCD2-FANCI complex To Be Published
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3LWK
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![BU of 3lwk by Molmil](/molmil-images/mine/3lwk) | Crystal structure of human Beta-crystallin A4 (CRYBA4) | 分子名称: | Beta-crystallin A4, GLYCEROL, PHOSPHATE ION | 著者 | Chaikuad, A, Shafqat, N, Krojer, T, Yue, W.W, Cocking, R, Vollmar, M, Muniz, J.R.C, Pike, A.C.W, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2010-02-24 | 公開日 | 2010-03-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of human Beta-crystallin A4 (CRYBA4) To be Published
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8ZJE
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![BU of 8zje by Molmil](/molmil-images/mine/8zje) | Cryo-EM structure of kisspeptin receptor bound to TAK-448 | 分子名称: | ACY-DTY-HYP-ASN-THR-PHE-XZA-LEU-NMM-TRP-NH2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Shen, S, Liu, H, Xu, H.E. | 登録日 | 2024-05-14 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Cryo-EM structure of kisspeptin receptor bound to TAK-448 To Be Published
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9FVT
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9CPG
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![BU of 9cpg by Molmil](/molmil-images/mine/9cpg) | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1 | 分子名称: | 4-carbamimidamidophenyl 4-carbamimidamidobenzoate, RNA (5'-R(*GP*AP*CP*AP*GP*CP*UP*GP*CP*UP*GP*UP*C)-3') | 著者 | Chen, J.L, Taghavi, A, Disney, M.D, Fountain, M.A, Childs-Disney, J.L. | 登録日 | 2024-07-18 | 公開日 | 2024-08-07 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1. Bioorg.Med.Chem.Lett., 2024
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9EME
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![BU of 9eme by Molmil](/molmil-images/mine/9eme) | AL amyloid fibril from the FOR103 light chain | 分子名称: | lambda 3 immunoglobulin light chain fragment, residues 2-116 | 著者 | Pfeiffer, P.B, Karimi-Farsijani, S, Kupfer, N, Schmidt, M, Faendrich, M. | 登録日 | 2024-03-08 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis. Nat Commun, 15, 2024
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9EZZ
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![BU of 9ezz by Molmil](/molmil-images/mine/9ezz) | |
9G1Y
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![BU of 9g1y by Molmil](/molmil-images/mine/9g1y) | |
9ERX
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![BU of 9erx by Molmil](/molmil-images/mine/9erx) | Structural basis of D9-THC analog activity at the Cannabinoid 1 receptor | 分子名称: | (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol, Antibody ScFv16 Fab fragment, Cannabinoid receptor 1, ... | 著者 | Thorsen, T.S, Kulkarni, Y, Boggild, A, Drace, T, Nissen, P, Gajhede, M, Boesen, T, Kastrup, J.S, Gloriam, D. | 登録日 | 2024-03-25 | 公開日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of Delta 9 -THC analog activity at the Cannabinoid 1 receptor. Res Sq, 2024
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3LXL
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![BU of 3lxl by Molmil](/molmil-images/mine/3lxl) | |
9G2G
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![BU of 9g2g by Molmil](/molmil-images/mine/9g2g) | Staphylococcus aureus MazF in complex with nanobody 5 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoribonuclease MazF, Nanobody 5 | 著者 | Prolic-Kalinsek, M, Zorzini, V, Haesaerts, S, Loris, R. | 登録日 | 2024-07-10 | 公開日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (1.80048239 Å) | 主引用文献 | Nanobody-mediated activation and inhibition of Staphylococcus aureus MazF To Be Published
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9F0E
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6DLQ
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![BU of 6dlq by Molmil](/molmil-images/mine/6dlq) | |
6QQA
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![BU of 6qqa by Molmil](/molmil-images/mine/6qqa) | |
6DLT
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![BU of 6dlt by Molmil](/molmil-images/mine/6dlt) | PRPP Riboswitch bound to PRPP, native structure | 分子名称: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, MAGNESIUM ION, PRPP Riboswitch, ... | 著者 | Peselis, A, Serganov, A. | 登録日 | 2018-06-02 | 公開日 | 2018-11-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | ykkC riboswitches employ an add-on helix to adjust specificity for polyanionic ligands. Nat. Chem. Biol., 14, 2018
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6QQF
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9BIU
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![BU of 9biu by Molmil](/molmil-images/mine/9biu) | Cryo-EM structure of the mammalian peptide transporter PepT2 bound to cloxacillin, pose 2 | 分子名称: | CLOXACILLIN, Solute carrier family 15 member 2, nanobody | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | 登録日 | 2024-04-24 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for antibiotic transport and inhibition in the mammalian proton-coupled peptide transporter, PepT2 To Be Published
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8XJ3
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8ZJD
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![BU of 8zjd by Molmil](/molmil-images/mine/8zjd) | Cryo-EM structure of kisspeptin receptor bound to KP-10 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, ... | 著者 | Shen, S, Liu, H, Xu, H.E. | 登録日 | 2024-05-14 | 公開日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Cryo-EM structure of kisspeptin receptor bound to KP-10 To Be Published
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8ZMR
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![BU of 8zmr by Molmil](/molmil-images/mine/8zmr) | Vesamicol-bound VAChT | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol | 著者 | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | 登録日 | 2024-05-23 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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8XUD
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9G4G
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9G5Z
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![BU of 9g5z by Molmil](/molmil-images/mine/9g5z) | |