2CUU
| Crystal structure of spin labeled T4 Lysozyme (V131R1) | 分子名称: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, CHLORIDE ION, ... | 著者 | Fleissner, M.R, Cascio, D, Sawaya, M.R, Hideg, K, Hubbell, W.L. | 登録日 | 2005-05-28 | 公開日 | 2006-08-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural origin of weakly ordered nitroxide motion in spin-labeled proteins Protein Sci., 18, 2009
|
|
2FUD
| Human Cathepsin S with Inhibitor CRA-27566 | 分子名称: | N-{(1R)-2-[(4-CYANO-1,1-DIOXIDOTETRAHYDRO-2H-THIOPYRAN-4-YL)AMINO]-2-OXO-1-[(TRIMETHYLSILYL)METHYL]ETHYL}MORPHOLINE-4-CARBOXAMIDE, cathepsin S | 著者 | Somoza, J.R. | 登録日 | 2006-01-26 | 公開日 | 2006-08-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Human Cathepsin S with Inhibitor CRA-27566 To be Published
|
|
2FTD
| Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound | 分子名称: | Cathepsin K, N-[(1S)-1-({[(3S,4S,7R)-3-HYDROXY-7-METHYL-1-(PYRIDIN-2-YLSULFONYL)-2,3,4,7-TETRAHYDRO-1H-AZEPIN-4-YL]AMINO}CARBONYL)-3-METHYLBUTYL]-1-BENZOFURAN-2-CARBOXAMIDE | 著者 | Yamashita, D.S, Baoguang, Z. | 登録日 | 2006-01-24 | 公開日 | 2007-01-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure activity relationships of 5-, 6-, and 7-methyl-substituted azepan-3-one cathepsin K inhibitors. J.Med.Chem., 49, 2006
|
|
2FQI
| dual binding modes of a novel series of DHODH inhibitors | 分子名称: | 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID, ACETATE ION, Dihydroorotate dehydrogenase, ... | 著者 | Baumgartner, R, Leban, J. | 登録日 | 2006-01-18 | 公開日 | 2007-01-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dual binding mode of a novel series of DHODH inhibitors. J.Med.Chem., 49, 2006
|
|
2FRQ
| Human Cathepsin S with Inhibitor CRA-26871 | 分子名称: | N-[4-(AMINOMETHYL)-1,1-DIOXIDOTETRAHYDRO-2H-THIOPYRAN-4-YL]-3-(1-METHYLCYCLOPENTYL)-N~2~-[(1E)-N-(PHENYLSULFONYL)ETHANIMIDOYL]-L-ALANINAMIDE, cathepsin S | 著者 | Somoza, J.R. | 登録日 | 2006-01-19 | 公開日 | 2006-07-25 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Human Cathepsin S with Inhibitor CRA-26871 To be Published
|
|
1E8X
| STRUCTURAL INSIGHTS INTO PHOSHOINOSITIDE 3-KINASE ENZYMATIC MECHANISM AND SIGNALLING | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, LUTETIUM (III) ION, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | 著者 | Walker, E.H, Perisic, O, Ried, C, Stephens, L, Williams, R.L. | 登録日 | 2000-10-03 | 公開日 | 2000-10-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural Determinations of Phosphoinositide 3-Kinase Inhibition by Wortmannin, Ly294002, Quercetin, Myricetin and Staurosporine Mol.Cell, 6, 2000
|
|
1J0J
| |
1F3S
| Solution Structure of DNA Sequence GGGTTCAGG Forms GGGG Tetrade and G(C-A) Triad. | 分子名称: | DNA (5'-D(*GP*GP*GP*TP*TP*CP*AP*GP*G)-3') | 著者 | Kettani, A, Basu, G, Gorin, A, Majumdar, A, Skripkin, E, Patel, D.J. | 登録日 | 2000-06-06 | 公開日 | 2000-11-13 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | A two-stranded template-based approach to G.(C-A) triad formation: designing novel structural elements into an existing DNA framework. J.Mol.Biol., 301, 2000
|
|
2IDH
| |
2JB5
| Fab fragment in complex with small molecule hapten, crystal form-1 | 分子名称: | 2-{(1E,3Z,5E,7E)-7-[3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-1,3-DIHYDRO-2H-INDOL-2-YLIDENE]-4-METHYLHEPTA-1,3,5-TRIEN-1-YL}-3,3-DIMETHYL-5-SULFO-1-(2-SULFOETHYL)-3H-INDOLIUM, FAB FRAGMENT MOR03268 HEAVY CHAIN, FAB FRAGMENT MOR03268 LIGHT CHAIN | 著者 | Hillig, R.C, Baesler, S, Malawski, G, Badock, V, Bahr, I, Schirner, M, Licha, K. | 登録日 | 2006-12-03 | 公開日 | 2008-01-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Fab Mor03268 Triggers Absorption Shift of a Diagnostic Dye Via Packaging in a Solvent-Shielded Fab Dimer Interface J.Mol.Biol., 377, 2008
|
|
1RKM
| STRUCTURE OF OPPA | 分子名称: | OLIGO-PEPTIDE BINDING PROTEIN | 著者 | Sleigh, S.H, Tame, J.R.H, Wilkinson, A.J. | 登録日 | 1997-03-25 | 公開日 | 1997-07-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Peptide binding in OppA, the crystal structures of the periplasmic oligopeptide binding protein in the unliganded form and in complex with lysyllysine. Biochemistry, 36, 1997
|
|
1KEE
| Inactivation of the Amidotransferase Activity of Carbamoyl Phosphate Synthetase by the Antibiotic Acivicin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Carbamoyl-phosphate synthetase large chain, ... | 著者 | Miles, B.W, Thoden, J.B, Holden, H.M, Raushel, F.M. | 登録日 | 2001-11-15 | 公開日 | 2001-12-21 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin. J.Biol.Chem., 277, 2002
|
|
1PAU
| |
1KXH
| Crystal structure of the complex between an inactive mutant of psychrophilic alpha-amylase (D174N) and acarbose | 分子名称: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Aghajari, N, Haser, R. | 登録日 | 2002-01-31 | 公開日 | 2002-06-19 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystallographic evidence of a transglycosylation reaction: ternary complexes of a psychrophilic alpha-amylase. Biochemistry, 41
|
|
1JDB
| CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE, CHLORIDE ION, ... | 著者 | Thoden, J.B, Holden, H.M, Wesenberg, G, Raushel, F.M, Rayment, I. | 登録日 | 1997-03-25 | 公開日 | 1998-06-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution. Acta Crystallogr.,Sect.D, 55, 1999
|
|
1P11
| |
1P12
| |
1GMC
| THE X-RAY CRYSTAL STRUCTURE OF THE TETRAHEDRAL INTERMEDIATE OF GAMMA-CHYMOTRYPSIN IN HEXANE | 分子名称: | GAMMA-CHYMOTRYPSIN A, PRO GLY ALA TYR PEPTIDE | 著者 | Yennawar, N.H, Yennawar, H.P, Banerjee, S, Farber, G.K. | 登録日 | 1993-08-20 | 公開日 | 1993-10-31 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray crystal structure of gamma-chymotrypsin in hexane. Biochemistry, 33, 1994
|
|
7V9K
| Telomeric tetranucleosome | 分子名称: | DNA (539-mer), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | 著者 | Soman, A. | 登録日 | 2021-08-25 | 公開日 | 2022-07-27 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Columnar structure of human telomeric chromatin. Nature, 609, 2022
|
|
1O8W
| Radiation-reduced Tryparedoxin-I | 分子名称: | TRYPAREDOXIN | 著者 | Alphey, M.S, Bond, C.S, Hunter, W.N. | 登録日 | 2002-12-09 | 公開日 | 2003-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
|
|
1O7U
| Radiation induced tryparedoxin-I | 分子名称: | TRYPAREDOXIN | 著者 | Alphey, M.S, Bond, C.S, McSweeney, S.M, Hunter, W.N. | 登録日 | 2002-11-14 | 公開日 | 2003-04-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
|
|
1O85
| Radiation-reduced Tryparedoxin-I | 分子名称: | TRYPAREDOXIN | 著者 | Alphey, M.S, Bond, C.S, Hunter, W.N. | 登録日 | 2002-11-25 | 公開日 | 2003-04-24 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function J.Biol.Chem., 278, 2003
|
|
1CXH
| COMPLEX OF CGTASE WITH MALTOTETRAOSE AT ROOM TEMPERATURE AND PH 9.6 BASED ON DIFFRACTION DATA OF A CRYSTAL SOAKED WITH MALTOHEPTAOSE | 分子名称: | CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | 著者 | Knegtel, R.M.A, Strokopytov, B.V, Dijkstra, B.W. | 登録日 | 1995-07-31 | 公開日 | 1995-12-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products. J.Biol.Chem., 270, 1995
|
|
2BOF
| Catalytic domain of endo-1,4-glucanase Cel6A mutant Y73S from Thermobifida fusca in complex with cellotetrose | 分子名称: | ENDOGLUCANASE E-2, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Larsson, A.M, Bergfors, T, Dultz, E, Irwin, D.C, Roos, A, Driguez, H, Wilson, D.B, Jones, T.A. | 登録日 | 2005-04-10 | 公開日 | 2005-10-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal Structure of Thermobifida Fusca Endoglucanase Cel6A in Complex with Substrate and Inhibitor: The Role of Tyrosine Y73 in Substrate Ring Distortion. Biochemistry, 44, 2005
|
|
2BE3
| |