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7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-17
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
4K76
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BU of 4k76 by Molmil
CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36-TRL (ANSRWPTTRL)
分子名称: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36-TRL peptide
著者Amacher, J.F, Madden, D.R.
登録日2013-04-16
公開日2014-02-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Structure, 22, 2014
2ROT
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BU of 2rot by Molmil
Structure of chimeric variant of SH3 domain- SHH
分子名称: Spectrin alpha chain, brain
著者Kutyshenko, N.P, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, Y.A, Gushchina, L.V, Khristoforov, V.S, Filimonov, V.V.
登録日2008-04-10
公開日2009-04-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the chimeric SH3 domains, SHH- and SHA-"Bergeracs".
Biochim.Biophys.Acta, 1794, 2009
6JPR
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BU of 6jpr by Molmil
Crystal structure of Phycocyanin from Nostoc sp. R76DM
分子名称: GLYCEROL, PHYCOCYANOBILIN, Phycocyanin, ...
著者Sonani, R.R, Gupta, G.D, Rastogi, R.P, Patel, S.N, Madamwar, D, Kumar, V.
登録日2019-03-27
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Phylogenetic and crystallographic analysis of Nostoc phycocyanin having blue-shifted spectral properties.
Sci Rep, 9, 2019
2M02
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BU of 2m02 by Molmil
3D structure of cap-gly domain of mammalian dynactin determined by magic angle spinning NMR spectroscopy
分子名称: Dynactin subunit 1
著者Yan, S, Hou, G, Schwieters, C.D, Ahmed, S, Williams, J.C, Polenova, T.
登録日2012-10-15
公開日2013-05-08
最終更新日2024-05-15
実験手法SOLID-STATE NMR
主引用文献Three-Dimensional Structure of CAP-Gly Domain of Mammalian Dynactin Determined by Magic Angle Spinning NMR Spectroscopy: Conformational Plasticity and Interactions with End-Binding Protein EB1.
J.Mol.Biol., 425, 2013
6JQF
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BU of 6jqf by Molmil
Crystallization analysis of a beta-N-acetylhexosaminidase (Am2136) from Akkermansia muciniphila
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glycoside hydrolase, ...
著者Zhang, M, Chen, X.
登録日2019-03-31
公開日2019-12-11
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Biochemical characteristics and crystallographic evidence for substrate-assisted catalysis of a beta-N-acetylhexosaminidase in Akkermansia muciniphila.
Biochem.Biophys.Res.Commun., 517, 2019
6W7M
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BU of 6w7m by Molmil
30S-Inactive-high-Mg2+ + carbon layer
分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Jahagirdar, D, Jha, V, Basu, B, Gomez-Blanco, J, Vargas, J, Ortega, J.
登録日2020-03-19
公開日2020-10-21
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Alternative conformations and motions adopted by 30S ribosomal subunits visualized by cryo-electron microscopy.
Rna, 26, 2020
6VVD
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BU of 6vvd by Molmil
Legionella pneumophila Lpg2603 kinase bound to IP6
分子名称: Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE
著者Tomchick, D.R, Tagliabracci, V.S, Sreelatha, A.
登録日2020-02-17
公開日2020-04-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献ALegionellaeffector kinase is activated by host inositol hexakisphosphate.
J.Biol.Chem., 295, 2020
4K97
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BU of 4k97 by Molmil
Structure of Ternary Complex of cGAS with dsDNA and Bound ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, DNA-F, ...
著者Gao, P, Wu, Y, Patel, D.J.
登録日2013-04-19
公開日2013-05-15
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase.
Cell(Cambridge,Mass.), 153, 2013
2RI1
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BU of 2ri1 by Molmil
Crystal Structure of glucosamine 6-phosphate deaminase (NagB) with GlcN6P from S. mutans
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Glucosamine-6-phosphate deaminase
著者Liu, C, Li, D, Su, X.D.
登録日2007-10-10
公開日2008-03-25
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Ring-opening mechanism revealed by crystal structures of NagB and its ES intermediate complex
J.Mol.Biol., 379, 2008
4V0N
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BU of 4v0n by Molmil
Crystal structure of BBS1N in complex with ARL6DN, soaked with mercury
分子名称: ARF-LIKE SMALL GTPASE, BARDET-BIEDL SYNDROME 1 PROTEIN, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Mourao, A, Lorentzen, E.
登録日2014-09-17
公開日2014-11-19
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (3.131 Å)
主引用文献Structural Basis for Membrane Targeting of the Bbsome by Arl6
Nat.Struct.Mol.Biol., 21, 2014
2RER
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BU of 2rer by Molmil
Crystal structure of the aromatase/cyclase domain of TcmN from Streptomyces glaucescens
分子名称: Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmN
著者Ames, B.D, Korman, T.P, Vu, T.N, Tsai, S.C.
登録日2007-09-26
公開日2008-04-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2M5J
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BU of 2m5j by Molmil
Solution structure of the periplasmic signaling domain of HasR, a TonB-dependent outer membrane heme transporter
分子名称: HasR protein
著者Malki, I, Cardoso de Amorim, G, Prochnicka-Chalufour, A, Simenel, C, Delepierre, M, Izadi-Pruneyre, N.
登録日2013-02-26
公開日2014-03-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Interaction of a Partially Disordered Antisigma Factor with Its Partner, the Signaling Domain of the TonB-Dependent Transporter HasR
Plos One, 9, 2014
4KPC
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BU of 4kpc by Molmil
Crystal structure of the nucleoside diphosphate kinase b from Leishmania braziliensis
分子名称: Nucleoside diphosphate kinase b, PHOSPHATE ION
著者Vieira, P.S, Giuseppe, P.O, Santos, C.R, Cunha, E.M.F, de Oliveira, A.H.C, Murakami, M.T.
登録日2013-05-13
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and biophysical characterization of the nucleoside diphosphate kinase from Leishmania braziliensis.
Bmc Struct.Biol., 15, 2015
6WA6
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BU of 6wa6 by Molmil
Structure of the Chlamydia pneumoniae CdsV protein
分子名称: GLYCEROL, Low calcium response locus protein D
著者Jensen, J.L, Spiller, B.W.
登録日2020-03-24
公開日2020-09-30
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献"The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm".
Plos Pathog., 16, 2020
6JCT
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BU of 6jct by Molmil
AAV5 in neutral condition at 3.18 Ang
分子名称: Capsid protein
著者Lou, Z, Zhang, R.
登録日2019-01-30
公開日2019-07-31
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
4KCL
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BU of 4kcl by Molmil
Structure of neuronal nitric oxide synthase heme domain in complex with N-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino)ethyl)phenyl)thiophene-2-carboximidamide
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, N-(4-{2-[(3-{[(E)-imino(thiophen-2-yl)methyl]amino}benzyl)amino]ethyl}phenyl)thiophene-2-carboximidamide, ...
著者Li, H, Poulos, T.L.
登録日2013-04-24
公開日2014-02-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma.
J.Med.Chem., 57, 2014
6JDJ
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BU of 6jdj by Molmil
Crystal structure of AcrIIC2 dimer in complex with partial Nme1Cas9
分子名称: AcrIIC2, CRISPR-associated endonuclease Cas9
著者Cheng, Z, Huang, X, Sun, W, Wang, Y.
登録日2019-02-01
公開日2019-05-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2.
Nat Commun, 10, 2019
6JDR
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BU of 6jdr by Molmil
Crystal structure of methylated PRRSV nsp10 (helicase)
分子名称: PP1b, SULFATE ION, ZINC ION
著者Deng, Z, Tang, C, Chen, Z.
登録日2019-02-02
公開日2020-02-05
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Helicase of Type 2 Porcine Reproductive and Respiratory Syndrome Virus Strain HV Reveals a Unique Structure.
Viruses, 12, 2020
6JEB
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BU of 6jeb by Molmil
crystal structure of a beta-N-acetylhexosaminidase
分子名称: ACETAMIDE, Beta-N-acetylhexosaminidase, ZINC ION
著者Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M.
登録日2019-02-05
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila.
Biochem. Biophys. Res. Commun., 511, 2019
2RHK
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BU of 2rhk by Molmil
Crystal structure of influenza A NS1A protein in complex with F2F3 fragment of human cellular factor CPSF30, Northeast Structural Genomics Targets OR8C and HR6309A
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cleavage and polyadenylation specificity factor subunit 4, NITRATE ION, ...
著者Das, K, Ma, L.-C, Xiao, R, Radvansky, B, Aramini, J, Zhao, L, Arnold, E, Krug, R.M, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2007-10-09
公開日2008-07-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural basis for suppression of a host antiviral response by influenza A virus.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4V6X
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BU of 4v6x by Molmil
Structure of the human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
登録日2013-02-27
公開日2014-07-09
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
4USS
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BU of 4uss by Molmil
Populus trichocarpa glutathione transferase X1-1 (GHR1), complexed with glutathione
分子名称: GLUTATHIONE, GLUTATHIONYL HYDROQUINONE REDUCTASE, PHOSPHATE ION
著者Lallement, P.A, Meux, E, Gualberto, J.M, Dumaracay, S, Favier, F, Didierjean, C, Saul, F, Haouz, A, Morel-Rouhier, M, Gelhaye, E, Rouhier, N, Hecker, A.
登録日2014-07-13
公開日2014-12-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Glutathionyl-Hydroquinone Reductases from Poplar are Plastidial Proteins that Deglutathionylate Both Reduced and Oxidized Glutathionylated Quinones.
FEBS Lett., 589, 2015
6JHY
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BU of 6jhy by Molmil
Crystal Structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein
著者Lu, G, Cheng, Y, Ye, F.
登録日2019-02-19
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the S1 subunit N-terminal domain from DcCoV UAE-HKU23 spike protein.
Virology, 535, 2019
7AQE
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BU of 7aqe by Molmil
Structure of SARS-CoV-2 Main Protease bound to UNC-2327
分子名称: 3C-like proteinase, CHLORIDE ION, DIMETHYL SULFOXIDE, ...
著者Guenther, S, Reinke, P, Meents, A.
登録日2020-10-21
公開日2021-03-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease.
Science, 372, 2021

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