8Z9Q
 
 | | Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation | | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-23 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8YXX
 | | TRIP4 ASCH domain in complex with a 12bp dsDNA (5'-TGAGGTACCTCG-3') | | 分子名称: | Activating signal cointegrator 1, DNA (5'-D(*CP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*CP*G)-3') | | 著者 | Ding, J, Yang, H, Hu, C. | | 登録日 | 2024-04-03 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Biochemical and structural characterization of the DNA-binding properties of human TRIP4 ASCH domain reveals insights into its functional role.
Structure, 2024
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9F3D
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8Z8X
 | | Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation | | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Polymerase acidic protein, Polymerase basic protein 2, ... | | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | | 登録日 | 2024-04-22 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses.
Nat Commun, 15, 2024
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8XF1
 | | Crystal structure of the dissociated C-phycocyanin beta-chain from Thermoleptolyngbya sp. O-77 | | 分子名称: | C-phycocyanin beta chain, PHYCOCYANOBILIN | | 著者 | Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S. | | 登録日 | 2023-12-13 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
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8ZMO
 | | Structure of a triple-helix region of human Collagen type XVII from Trautec | | 分子名称: | collagen type XVII | | 著者 | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | | 登録日 | 2024-05-23 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of a triple-helix region of human Collagen type XVII from Trautec
To Be Published
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8XPB
 | | Crystal structure of d(ACGCCGT/ACGGCGT) in complex with Echinomycin | | 分子名称: | 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*CP*CP*GP*T)-3'), DNA (5'-D(P*AP*CP*GP*GP*CP*GP*T)-3'), ... | | 著者 | Hou, M.H, Huang, H.T, Lin, S.M, Neidle, S. | | 登録日 | 2024-01-03 | | 公開日 | 2024-05-29 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis of water-mediated cis Watson-Crick/Hoogsteen base-pair formation in non-CpG methylation.
Nucleic Acids Res., 2024
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9ENC
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8XO9
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8ZMW
 | | Structure of a triple-helix region of human Collagen type VII from Trautec | | 分子名称: | ACETATE ION, collagen type VII | | 著者 | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | | 登録日 | 2024-05-24 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of a triple-helix region of human Collagen type VII from Trautec
To Be Published
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8YG2
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8YJ6
 | | Characerization of a novel format scFvXVHH single-chain Biparatopic antibody against a metal binding protein, MtsA | | 分子名称: | Iron ABC transporter substrate-binding lipoprotein MtsA, ZINC ION | | 著者 | Ito, S, Nagatoishi, S, Nakakido, M, Tsumoto, K. | | 登録日 | 2024-03-01 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Protein Sci., 33, 2024
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9F3E
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3LXH
 | | Crystal Structure of Cytochrome P450 CYP101D1 | | 分子名称: | 1,4-DIETHYLENE DIOXIDE, Cytochrome P450, PHOSPHATE ION, ... | | 著者 | Yang, W, Bell, S.G, Wang, H, Bartlam, M, Wong, L.L, Rao, Z. | | 登録日 | 2010-02-25 | | 公開日 | 2010-06-23 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular characterization of a class I P450 electron transfer system from Novosphingobium aromaticivorans DSM12444
J.Biol.Chem., 285, 2010
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3LRN
 | | Crystal structure of human RIG-I CTD bound to a 14 bp GC 5' ppp dsRNA | | 分子名称: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION | | 著者 | Li, P. | | 登録日 | 2010-02-11 | | 公開日 | 2010-06-02 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
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9BIS
 | | Cryo-EM structure of the mammalian peptide transporter PepT2 bound to amoxicillin | | 分子名称: | 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, Solute carrier family 15 member 2, nanobody | | 著者 | Parker, J.L, Deme, J.C, Lea, S.M, Newstead, S. | | 登録日 | 2024-04-24 | | 公開日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis for antibiotic transport and inhibition in the mammalian proton-coupled peptide transporter, PepT2
To Be Published
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8XJE
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6DBM
 | | Tyk2 with compound 23 | | 分子名称: | Non-receptor tyrosine-protein kinase TYK2, [(1S)-2,2-difluorocyclopropyl][(1R,5S)-3-{2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone | | 著者 | Vajdos, F.F. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-29 | | 最終更新日 | 2018-11-07 | | 実験手法 | X-RAY DIFFRACTION (2.368 Å) | | 主引用文献 | Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841).
J. Med. Chem., 61, 2018
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9G48
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8ZMM
 | | Structure of a triple-helix region of human Collagen type IV from Trautec | | 分子名称: | collagen type IV | | 著者 | Chu, Y, Zhai, Y, Fan, X, Fu, S, Li, J, Wu, X, Cai, H, Wang, X, Li, D, Feng, P, Cao, K, Qian, S. | | 登録日 | 2024-05-23 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure of a triple-helix region of human Collagen type IV from Trautec
To Be Published
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3LSB
 | | Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN from Arthrobacter aurescens TC1 complexed with zinc and ametrin | | 分子名称: | N-ethyl-N'-(1-methylethyl)-6-(methylsulfanyl)-1,3,5-triazine-2,4-diamine, Triazine hydrolase, ZINC ION | | 著者 | Fedorov, A.A, Fedorov, E.V, Seffernick, J, Wackett, L.P, Almo, S.C. | | 登録日 | 2010-02-12 | | 公開日 | 2010-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.932 Å) | | 主引用文献 | Crystal structure of the mutant E241Q of atrazine chlorohydrolase TrzN
from Arthrobacter aurescens TC1 complexed with zinc and Ametryn
To be Published
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9G5L
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8YFI
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3LSP
 | | Crystal Structure of DesT bound to desCB promoter and oleoyl-CoA | | 分子名称: | DNA (5'-D(*TP*CP*AP*AP*TP*CP*GP*AP*GP*TP*CP*AP*AP*CP*AP*AP*GP*CP*GP*TP*TP*CP*AP*CP*TP*GP*AP*TP*GP*TP*A)-3'), DNA (5'-D(*TP*TP*AP*CP*AP*TP*CP*AP*GP*TP*GP*AP*AP*CP*GP*CP*TP*TP*GP*TP*TP*GP*AP*CP*TP*CP*GP*AP*TP*TP*G)-3'), DesT, ... | | 著者 | Miller, D.J, White, S.W. | | 登録日 | 2010-02-12 | | 公開日 | 2010-08-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Structural basis for the transcriptional regulation of membrane lipid homeostasis.
Nat.Struct.Mol.Biol., 17, 2010
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8XAX
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