9BIS
Cryo-EM structure of the mammalian peptide transporter PepT2 bound to amoxicillin
Summary for 9BIS
Entry DOI | 10.2210/pdb9bis/pdb |
EMDB information | 44600 |
Descriptor | Solute carrier family 15 member 2, nanobody, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total) |
Functional Keywords | protein-coupled peptide transporter, peptide transport, antibiotics, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 2 |
Total formula weight | 97339.37 |
Authors | Parker, J.L.,Deme, J.C.,Lea, S.M.,Newstead, S. (deposition date: 2024-04-24, release date: 2024-07-24) |
Primary citation | Parker, J.L.,Deme, J.C.,Lichtinger, S.M.,Kuteyi, G.,Biggin, P.C.,Lea, S.M.,Newstead, S. Structural basis for antibiotic transport and inhibition in the mammalian proton-coupled peptide transporter, PepT2 To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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