PDB: 1957 件ウェブページステータス検索Chemie searchBIRD

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2NVY	RNA Polymerase II form II in 150 mM Mn+2 分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 45 kDa polypeptide, ... 著者 Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. 登録日 2006-11-13 公開日 2006-12-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
2NVT	RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP 分子名称: 5'-D(*GP*TP*AP*CP*TP*TP*G)-3', 5'-D(P*CP*AP*AP*GP*TP*AP*CP*TP*TP*AP*CP*GP*CP*CP*TP*GP*GP*TP*CP*TP*T)-3', 5'-R(*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3', ... 著者 Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D. 登録日 2006-11-13 公開日 2006-12-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.36 Å) 主引用文献 Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis Cell(Cambridge,Mass.), 127, 2006
7ORI	La Crosse virus polymerase at replication late-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
1DZF	RPB5 from S.cerevisiae 分子名称: DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 著者 Todone, F, Weinzierl, R.O.J, Brick, P, Onesti, S. 登録日 2000-02-25 公開日 2000-06-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Transcription Factor Interaction Target Proc.Natl.Acad.Sci.USA, 97, 2000
1N38	reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-URIDINE 5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-10-25 公開日 2002-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
7ORO	La Crosse virus polymerase at replication early-elongation stage 分子名称: La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
1N1H	Initiation complex of polymerase lambda3 from reovirus 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-10-17 公開日 2002-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
2HAI	Crystal structure of HCV NS5B RNA polymerase in complex with novel class of dihydropyrone-containing inhibitor. 分子名称: (6S)-6-CYCLOPENTYL-6-[2-(3-FLUORO-4-ISOPROPOXYPHENYL)ETHYL]-4-HYDROXY-5,6-DIHYDRO-2H-PYRAN-2-ONE, HEPATITIS C VIRUS NS5B RNA POLYMERASE 著者 Li, H, Love, R.L. 登録日 2006-06-12 公開日 2006-09-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Identification and structure-based optimization of novel dihydropyrones as potent HCV RNA polymerase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
1N35	lambda3 elongation complex with four phosphodiester bond formed 分子名称: 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ... 著者 Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. 登録日 2002-10-25 公開日 2002-12-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
4C3I	Structure of 14-subunit RNA polymerase I at 3.0 A resolution, crystal form C2-100 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
4C3H	Structure of 14-subunit RNA polymerase I at 3.27 A resolution, crystal form C2-93 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.27 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
4C3J	Structure of 14-subunit RNA polymerase I at 3.35 A resolution, crystal form C2-90 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Fernandez-Tornero, C, Moreno-Morcillo, M, Rashid, U.J, Taylor, N.M.I, Ruiz, F.M, Gruene, T, Legrand, P, Steuerwald, U, Muller, C.W. 登録日 2013-08-24 公開日 2013-10-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Crystal Structure of the 14-Subunit RNA Polymerase I Nature, 502, 2013
3GTL	Backtracked RNA polymerase II complex with 13mer with G<>U mismatch 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.38 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3CQZ	Crystal structure of 10 subunit RNA polymerase II in complex with the inhibitor alpha-amanitin 分子名称: ALPHA-AMANITIN, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... 著者 Kaplan, C.D, Larsson, K.-M, Kornberg, R.D. 登録日 2008-04-03 公開日 2008-07-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The RNA Polymerase II Trigger Loop Functions in Substrate Selection and is Directly Targeted by Alpha-Amanitin. Mol.Cell, 30, 2008
3GTJ	Backtracked RNA polymerase II complex with 13mer RNA 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3GTK	Backtracked RNA polymerase II complex with 18mer RNA 分子名称: DNA (29-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3GTP	Backtracked RNA polymerase II complex with 24mer RNA 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
3GTM	Co-complex of Backtracked RNA polymerase II with TFIIS 分子名称: DNA (28-MER), DNA (5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... 著者 Wang, D, Bushnell, D.A, Huang, X, Westover, K.D, Levitt, M, Kornberg, R.D. 登録日 2009-03-27 公開日 2009-06-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution. Science, 324, 2009
7ORN	La Crosse virus polymerase at replication initiation stage 分子名称: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ... 著者 Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H. 登録日 2021-06-06 公開日 2022-02-16 最終更新日 2022-03-02 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription. Nat Commun, 13, 2022
4C2M	Structure of RNA polymerase I at 2.8 A resolution 分子名称: DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... 著者 Engel, C, Sainsbury, S, Cheung, A.C, Kostrewa, D, Cramer, P. 登録日 2013-08-19 公開日 2013-10-23 最終更新日 2015-08-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RNA Polymerase I Structure and Transcription Regulation. Nature, 502, 2013
4TYB	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: (2R)-morpholin-4-yl(phenyl)ethanenitrile, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-08 公開日 2015-05-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
4TY9	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: 5-(trifluoromethyl)pyridin-2-amine, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-08 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
4TYA	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: 4-(trifluoromethyl)benzoic acid, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-08 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
4TXS	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: (4-hydroxyphenyl)acetonitrile, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-07 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
4TY8	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline 分子名称: 6-methyl-2H-chromen-2-one, Polyprotein 著者 Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. 登録日 2014-07-08 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015

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