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8HL4
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Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
分子名称: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
著者Wang, Y.H, Zhou, J.
登録日2022-11-28
公開日2023-11-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.62 Å)
主引用文献Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Li, W, Cate, J.H.D.
登録日2019-04-18
公開日2019-06-19
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
8C01
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Enp1TAP_A population of yeast small ribosomal subunit precursors
分子名称: 18S rRNA precursor, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ...
著者Milkereit, P, Poell, G.
登録日2022-12-15
公開日2022-12-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Plos One, 18, 2023
8C00
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Enp1TAP-S21_A population of yeast small ribosomal subunit precursors depleted of rpS21/eS21
分子名称: 18S rRNA precursor, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ...
著者Milkereit, P, Poell, G.
登録日2022-12-15
公開日2022-12-28
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors.
Plos One, 18, 2023
6OY7
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X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-14
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OY5
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X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min
分子名称: DNA (5'-D(*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*CP*TP*CP*TP*GP*AP*TP*GP*CP*AP*G)-3'), DNA (5'-D(P*CP*CP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*AP*T)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-05-14
公開日2019-06-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6P67
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Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IL-7R 2B8 Fab heavy chain, ...
著者Walsh, S.T.R, Kashi, L, Kohnhorst, C.L.
登録日2019-06-03
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献New anti-IL-7R alpha monoclonal antibodies show efficacy against T cell acute lymphoblastic leukemia in pre-clinical models.
Leukemia, 34, 2020
8HL1
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BU of 8hl1 by Molmil
Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome
分子名称: 16s rRNA (1493-MER), 23s rRNA (3000-MER), 30S ribosomal protein S10, ...
著者Wang, Y.H, Zhou, J.
登録日2022-11-28
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.93 Å)
主引用文献Cryo-electron microscopy structure and translocation mechanism of the crenarchaeal ribosome.
Nucleic Acids Res., 51, 2023
6PAM
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Structure of a bacterial Atm1-family ABC transporter with MgADP bound
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION
著者Fan, C, Kaiser, J.T, Rees, D.C.
登録日2019-06-11
公開日2020-06-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P18
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Q21 transcription antitermination complex: loading complex
分子名称: DNA (67-MER) fragment carrying phage-21 pR' promoter and pause element, nontemplate strand, template strand, ...
著者Yin, Z, Ebright, R.H.
登録日2019-05-19
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6P4H
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BU of 6p4h by Molmil
Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2)
分子名称: 18S rRNA, IAPV-IRES, RACK1, ...
著者Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
登録日2019-05-27
公開日2019-09-18
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P4G
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BU of 6p4g by Molmil
Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1)
分子名称: 18S rRNA, IAPV-IRES, RACK1, ...
著者Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S.
登録日2019-05-27
公開日2019-09-18
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38, 2019
6P70
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X-ray crystal structure of bacterial RNA polymerase and pyrBI promoter complex
分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*CP*GP*AP*TP*CP*TP*TP*TP*GP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*TP*CP*CP*CP*GP*GP*CP*AP*AP*AP*TP*TP*GP*TP*CP*CP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Shin, Y, Murakami, K.S.
登録日2019-06-04
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.052 Å)
主引用文献Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
8I9T
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BU of 8i9t by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Dbp10-1
分子名称: 60S ribosomal protein L12-like protein, 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, ...
著者Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
登録日2023-02-07
公開日2023-05-17
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
8I9P
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BU of 8i9p by Molmil
Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - State Mak16
分子名称: 60S ribosomal protein L13, 60S ribosomal protein L14-like protein, 60S ribosomal protein L16-like protein, ...
著者Lau, B, Huang, Z, Beckmann, R, Hurt, E, Cheng, J.
登録日2023-02-07
公開日2023-05-17
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Mechanism of 5S RNP recruitment and helicase-surveilled rRNA maturation during pre-60S biogenesis.
Embo Rep., 24, 2023
6P7B
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BU of 6p7b by Molmil
Crystal structure of Fowlpox virus resolvase and substrate Holliday junction DNA complex
分子名称: DNA (29-MER), Holliday junction resolvase
著者Li, N, Shi, K, Rao, T, Banerjee, S, Aihara, H.
登録日2019-06-05
公開日2020-04-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.317 Å)
主引用文献Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase.
Sci Rep, 10, 2020
8CEP
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BU of 8cep by Molmil
Kasugamycin bound to the 30S body
分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S rRNA, 23S rRNA, ...
著者Paternoga, H, Beckert, B, Wilson, D.N.
登録日2023-02-02
公開日2023-07-19
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAI
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BU of 8cai by Molmil
Streptomycin and Hygromycin B bound to the 30S body
分子名称: 16S rRNA, 30S ribosomal protein S16, 30S ribosomal protein S2, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.08 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGK
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Lincomycin and Avilamycin bound to the 50S subunit
分子名称: (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 23S rRNA, 50S ribosomal protein L15, ...
著者Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
登録日2023-02-05
公開日2023-07-19
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.64 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGD
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Clindamycin bound to the 50S subunit
分子名称: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-03
公開日2023-07-26
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.98 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CMI
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Human Leukocyte Antigen class II allotype DR1 presenting SARS-CoV-2 Omicron (BA.1) Spike peptide S761-775
分子名称: 1,2-ETHANEDIOL, HLA class II histocompatibility antigen, DR alpha chain, ...
著者MacLachlan, B.J, Mason, G.H, Sourfield, D.O, Godkin, A.J, Rizkallah, P.J.
登録日2023-02-19
公開日2023-07-26
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4 + T cell immunity.
Cell Rep, 42, 2023
8CEU
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Retapamulin and Capreomycin bound to the 50S subunit
分子名称: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
著者Paternoga, H, Beckert, B, Wilson, D.N.
登録日2023-02-02
公開日2023-07-26
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.83 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGJ
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Streptomycin bound to the 30S body
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
著者Paternoga, H, Crowe-McAuliffe, C, Beckert, B, Wilson, D.N.
登録日2023-02-05
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.79 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CGR
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Apramycin bound to the 30S body
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S16, ...
著者Paternoga, H, Koller, T.O, Beckert, B, Wilson, D.N.
登録日2023-02-06
公開日2023-07-26
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.12 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023
8CAM
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BU of 8cam by Molmil
Evernimicin bound to the 50S subunit
分子名称: 23S rRNA, 50S ribosomal protein L15, 50S ribosomal protein L25, ...
著者Paternoga, H, Crowe-McAuliffe, C, Novacek, J, Wilson, D.N.
登録日2023-01-24
公開日2023-07-26
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (1.86 Å)
主引用文献Structural conservation of antibiotic interaction with ribosomes.
Nat.Struct.Mol.Biol., 30, 2023

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