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6OB1
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Structure of WHB in complex with Ubiquitin Variant
分子名称: Anaphase-promoting complex subunit 2, Ubiquitin
著者Edmond, R.W, Grace, C.R.
登録日2019-03-19
公開日2019-08-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc.Natl.Acad.Sci.USA, 116, 2019
7SVQ
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BU of 7svq by Molmil
Crystal Structure of L-galactose dehydrogenase from Spinacia oleracea in complex with NAD+
分子名称: L-galactose dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Santillan, J.A.V, Cabrejos, D.A.L, Pereira, H.M, Gomez, J.C.C, Garratt, R.C.
登録日2021-11-19
公開日2022-07-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural Characterization of L-Galactose Dehydrogenase: An Essential Enzyme for Vitamin C Biosynthesis.
Plant Cell.Physiol., 63, 2022
6TLG
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BU of 6tlg by Molmil
Ligand-free state of human 14-3-3 sigma isoform
分子名称: 14-3-3 protein sigma, DI(HYDROXYETHYL)ETHER, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-02
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
1GMI
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BU of 1gmi by Molmil
Structure of the c2 domain from novel protein kinase C epsilon
分子名称: MAGNESIUM ION, PROTEIN KINASE C, EPSILON TYPE
著者Ochoa, W.F, Garcia-Garcia, J, Fita, I, Corbalan-Garcia, S, Verdaguer, N, Gomez-Fernandez, J.C.
登録日2001-09-14
公開日2001-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the C2 Domain from Novel Protein Kinase Cepsilon. A Membrane Binding Model for Ca(2+ )-Independent C2 Domains
J.Mol.Biol., 311, 2001
7RIB
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BU of 7rib by Molmil
Griffithsin mutant Y28F/Y68F/Y110F
分子名称: Griffithsin, SULFATE ION, alpha-D-mannopyranose
著者Zhao, G, Sun, J, Bewley, C.A.
登録日2021-07-19
公開日2022-05-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献C 3 -Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity.
Acs Chem.Biol., 17, 2022
8WCK
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BU of 8wck by Molmil
FCP tetramer in Chaetoceros gracilis
分子名称: (3S,3'S,5R,5'R,6S,6'R,8'R)-3,5'-dihydroxy-8-oxo-6',7'-didehydro-5,5',6,6',7,8-hexahydro-5,6-epoxy-beta,beta-caroten-3'- yl acetate, CHLOROPHYLL A, Chlorophyll a/b-binding protein, ...
著者Feng, Y, Li, Z, Zhou, C, Shen, J.-R, Liu, C, Wang, W.
登録日2023-09-12
公開日2024-07-31
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural and spectroscopic insights into fucoxanthin chlorophyll a/c-binding proteins of diatoms in diverse oligomeric states.
Plant Commun., 2024
5M2Y
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BU of 5m2y by Molmil
Structure of TssK C-terminal domain from E. coli T6SS
分子名称: TssK C
著者Cambillau, C, Nguyen, V.S, Spinelli, S, Desmyter, A, Legrand, P.
登録日2016-10-13
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex.
Nat Microbiol, 2, 2017
8AAG
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BU of 8aag by Molmil
H1-bound palindromic nucleosome, state 1
分子名称: DNA/RNA (185-MER), Histone H1.0-B, Histone H2A type 1, ...
著者Alegrio Louro, J, Beinsteiner, B, Cheng, T.C, Patel, A.K.M, Boopathi, R, Angelov, D, Hamiche, A, Bednar, J, Kale, S, Dimitrov, S, Klaholz, B.
登録日2022-07-01
公開日2022-12-14
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms.
Structure, 31, 2023
6TLF
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BU of 6tlf by Molmil
human 14-3-3 sigma isoform in complex with IMP
分子名称: 14-3-3 protein sigma, INOSINIC ACID, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-02
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
8EV1
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Dual Modulators
分子名称: (3aR,4S,9bS)-4-(4-hydroxyphenyl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinoline-8-sulfonamide, (3aS,4R,9bR)-4-(4-hydroxyphenyl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[c]quinoline-8-sulfonamide, Estrogen Receptor, ...
著者Tinivella, A, Nwachukwu, J.C, Angeli, A, Foschi, F, Benatti, A.L, Pinzi, L, Izard, T, Ferraroni, M, Rangarajan, E.S, Christodoulou, M, Passarella, D, Supuran, C, Nettles, K.W, Rastelli, G.
登録日2022-10-19
公開日2022-12-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors.
Eur.J.Med.Chem., 246, 2022
6TM7
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BU of 6tm7 by Molmil
Human 14-3-3 sigma isoform in complex with PLP
分子名称: 14-3-3 protein sigma, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
著者Tassone, G, Pozzi, C, Mangani, S.
登録日2019-12-03
公開日2020-03-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction.
Acs Chem.Biol., 15, 2020
1HKU
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BU of 1hku by Molmil
CtBP/BARS: a dual-function protein involved in transcription corepression and Golgi membrane fission
分子名称: C-TERMINAL BINDING PROTEIN 3, FORMIC ACID, GLYCEROL, ...
著者Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M.
登録日2003-03-11
公開日2003-06-19
最終更新日2016-12-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission
Embo J., 22, 2003
5KLV
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BU of 5klv by Molmil
Structure of bos taurus cytochrome bc1 with fenamidone inhibited
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
著者Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z.
登録日2016-06-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
1HWV
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BU of 1hwv by Molmil
MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
分子名称: (1S)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
著者Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S.
登録日2001-01-10
公開日2001-03-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
1HX4
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BU of 1hx4 by Molmil
MOLECULAR TOPOLOGY OF POLYCYCLIC AROMATIC CARCINOGENS DETERMINES DNA ADDUCT CONFORMATION: A LINK TO TUMORIGENIC ACTIVITY
分子名称: (1R)-1,2,3,4-TETRAHYDRO-BENZO[C]PHENANTHRENE-2,3,4-TRIOL, 5'-D(*CP*CP*AP*TP*CP*GP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
著者Patel, D.J, Lin, C.H, Geacintov, N.E, Broyde, S, Huang, X, Kolbanovskii, A, Hingerty, B.E, Amin, S.
登録日2001-01-11
公開日2001-03-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Molecular topology of polycyclic aromatic carcinogens determines DNA adduct conformation: a link to tumorigenic activity.
J.Mol.Biol., 306, 2001
8OWG
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BU of 8owg by Molmil
Crystal structure of D1228V c-MET bound by compound 2
分子名称: 5-[3,5-bis(fluoranyl)phenyl]-1-[(1S)-1-phenylethyl]pyrimidine-2,4-dione, Hepatocyte growth factor receptor
著者Collie, G.W.
登録日2023-04-27
公開日2023-07-05
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.631 Å)
主引用文献Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor.
J.Med.Chem., 66, 2023
1EXQ
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BU of 1exq by Molmil
CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN
分子名称: CADMIUM ION, CHLORIDE ION, POL POLYPROTEIN, ...
著者Chen, J.C.-H, Krucinski, J, Miercke, L.J.W, Finer-Moore, J.S, Tang, A.H, Leavitt, A.D, Stroud, R.M.
登録日2000-05-03
公開日2000-11-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding.
Proc.Natl.Acad.Sci.USA, 97, 2000
1EV9
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BU of 1ev9 by Molmil
RAT GLUTATHIONE S-TRANSFERASE A1-1 MUTANT W21F WITH GSO3 BOUND
分子名称: GLUTATHIONE S-TRANSFERASE A1-1, GLUTATHIONE SULFONIC ACID, SULFATE ION
著者Adman, E.T, Le Trong, I, Stenkamp, R.E, Nieslanik, B.S, Dietze, E.C, Tai, G, Ibarra, C, Atkins, W.M.
登録日2000-04-19
公開日2001-02-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Localization of the C-terminus of rat glutathione S-transferase A1-1: crystal structure of mutants W21F and W21F/F220Y.
Proteins, 42, 2001
5LXV
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BU of 5lxv by Molmil
Crystal structure of Ruminococcus flavefaciens scaffoldin C cohesin in complex with a dockerin from an uncharacterized CBM-containing protein
分子名称: CALCIUM ION, Carbohydrate-binding protein WP_009985128, Scaffoldin C
著者Najmudin, S, Bule, P, Fontes, C.M.G.A.
登録日2016-09-22
公開日2016-10-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Single Binding Mode Integration of Hemicellulose-degrading Enzymes via Adaptor Scaffoldins in Ruminococcus flavefaciens Cellulosome.
J. Biol. Chem., 291, 2016
7A36
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BU of 7a36 by Molmil
Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea
分子名称: Proto-oncogene tyrosine-protein kinase Src, SODIUM ION, UREA
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 7 M urea
To be published
7A32
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Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 7.0
分子名称: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 7.0
To be published
1FLC
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BU of 1flc by Molmil
X-RAY STRUCTURE OF THE HAEMAGGLUTININ-ESTERASE-FUSION GLYCOPROTEIN OF INFLUENZA C VIRUS
分子名称: HAEMAGGLUTININ-ESTERASE-FUSION GLYCOPROTEIN, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Rosenthal, P.B, Zhang, X, Formanowski, F, Fitz, W, Wong, C.H, Meier-Ewert, H, Skehel, J.J, Wiley, D.C.
登録日1999-02-22
公開日2000-03-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus.
Nature, 396, 1998
7A37
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Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 3 M urea
分子名称: Proto-oncogene tyrosine-protein kinase Src, UREA
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant V111L-N113S-T114S in 3 M urea
To be published
7A33
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Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 3.0
分子名称: FORMIC ACID, Proto-oncogene tyrosine-protein kinase Src, SODIUM ION
著者Camara-Artigas, A, Plaza-Garrido, M, Salinas-Garcia, M.C.
登録日2020-08-18
公開日2021-08-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (0.96 Å)
主引用文献Crystal structure of the c-Src SH3 domain mutant S94A-T98D-V111L-N113S-T114S at pH 3.0
To be published
5XK1
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Structure of 8-mer DNA3
分子名称: DNA (5'-D(*GP*GP*AP*GP*CP*CP*CP*C)-3')
著者Liu, H.H, Gan, J.H.
登録日2017-05-04
公開日2017-12-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs.
Angew. Chem. Int. Ed. Engl., 56, 2017

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件を2024-08-14に公開中

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