5A61
 
 | | Crystal structure of full-length E. coli ygiF in complex with tripolyphosphate and two manganese ions. | | 分子名称: | 1,2-ETHANEDIOL, INORGANIC TRIPHOSPHATASE, MANGANESE (II) ION, ... | | 著者 | Martinez, J, Truffault, V, Hothorn, M. | | 登録日 | 2015-06-23 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
J.Biol.Chem., 290, 2015
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5A68
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4AH2
 | | HLA-DR1 with covalently linked CLIP106-120 in canonical orientation | | 分子名称: | GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN,DRB1-1 BETA CHAIN, ... | | 著者 | Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. | | 登録日 | 2012-02-03 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex.
J.Mol.Biol., 423, 2012
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7AOP
 | | Structure of NUDT15 in complex with inhibitor TH8321 | | 分子名称: | 2-azanyl-9-cyclohexyl-8-(2-methoxyphenyl)-3~{H}-purine-6-thione, MAGNESIUM ION, Nucleotide triphosphate diphosphatase NUDT15 | | 著者 | Rehling, D, Zhang, S.M, Helleday, T, Stenmark, P. | | 登録日 | 2020-10-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.
Cell Chem Biol, 28, 2021
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7AOM
 | | Structure of NUDT15 in complex with Ganciclovir triphosphate | | 分子名称: | Ganciclovir triphosphate, MAGNESIUM ION, Nucleotide triphosphate diphosphatase NUDT15 | | 著者 | Rehling, D, Zhang, S.M, Helleday, T, Stenmark, P. | | 登録日 | 2020-10-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | NUDT15-mediated hydrolysis limits the efficacy of anti-HCMV drug ganciclovir.
Cell Chem Biol, 28, 2021
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5A64
 | | Crystal structure of mouse thiamine triphosphatase in complex with thiamine triphosphate. | | 分子名称: | 1,2-ETHANEDIOL, THIAMINE TRIPHOSPHATASE, TRIETHYLENE GLYCOL, ... | | 著者 | Martinez, J, Truffault, V, Hothorn, M. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
J.Biol.Chem., 290, 2015
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5A60
 | | Crystal structure of full-length E. coli ygiF in complex with tripolyphosphate and two magnesium ions | | 分子名称: | 1,2-ETHANEDIOL, INORGANIC TRIPHOSPHATASE, MAGNESIUM ION, ... | | 著者 | Martinez, J, Truffault, V, Hothorn, M. | | 登録日 | 2015-06-23 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
J.Biol.Chem., 290, 2015
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4AEN
 | | HLA-DR1 with covalently linked CLIP106-120 in reversed orientation | | 分子名称: | GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. | | 登録日 | 2012-01-11 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex.
J.Mol.Biol., 423, 2012
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5A65
 | | Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions. | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Martinez, J, Truffault, V, Hothorn, M. | | 登録日 | 2015-06-24 | | 公開日 | 2015-08-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structural Determinants for Substrate Binding and Catalysis in Triphosphate Tunnel Metalloenzymes.
J.Biol.Chem., 290, 2015
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5JNE
 | | E2-SUMO-Siz1 E3-SUMO-PCNA complex | | 分子名称: | E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... | | 著者 | Lima, C.D, Streich Jr, F.C. | | 登録日 | 2016-04-29 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Capturing a substrate in an activated RING E3/E2-SUMO complex.
Nature, 536, 2016
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6D0Q
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6D0R
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8DR4
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8DR7
 | | Open state of RFC:PCNA bound to a nicked dsDNA | | 分子名称: | DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ... | | 著者 | Schrecker, M, Hite, R.K. | | 登録日 | 2022-07-20 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
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8DR3
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117E
 | | THE R78K AND D117E ACTIVE SITE VARIANTS OF SACCHAROMYCES CEREVISIAE SOLUBLE INORGANIC PYROPHOSPHATASE: STRUCTURAL STUDIES AND MECHANISTIC IMPLICATIONS | | 分子名称: | MANGANESE (II) ION, PHOSPHATE ION, PROTEIN (INORGANIC PYROPHOSPHATASE) | | 著者 | Tuominen, V, Heikinheimo, P, Kajander, T, Torkkel, T, Hyytia, T, Kapyla, J, Lahti, R, Cooperman, B.S, Goldman, A. | | 登録日 | 1998-09-15 | | 公開日 | 1998-12-23 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: structural studies and mechanistic implications.
J.Mol.Biol., 284, 1998
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8DR5
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8DR1
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6AC7
 | | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter | | 分子名称: | 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*GP*AP*GP*GP*CP*GP*GP*GP*GP*CP*TP*TP*GP*GP*G)-3' | | 著者 | Sengar, A, Vandana, J.J, Chambers, V.S, Di Antonio, M, Winnerdy, F.R, Balasubramanian, S, Phan, A.T. | | 登録日 | 2018-07-25 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a (3+1) hybrid G-quadruplex in the PARP1 promoter.
Nucleic Acids Res., 47, 2019
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2HN8
 | | Structural characterization and oligomerization of PB1-F2, a pro-apoptotic influenza A virus protein | | 分子名称: | Protein PB1-F2 | | 著者 | Bruns, K, Studtrucker, N, Sharma, A, Fossen, T, Mitzner, D, Eissmann, A, Tessmer, U, Roder, R, Henklein, P, Wray, V, Schubert, U. | | 登録日 | 2006-07-12 | | 公開日 | 2006-11-07 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural characterization and oligomerization of PB1-F2, a pro-apoptotic influenza A virus protein.
J.Biol.Chem., 282, 2007
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4APQ
 | | Crystal structure of autoreactive-Valpha14-Vbeta6 NKT TCR in complex with CD1d-sulfatide | | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN-PRESENTING GLYCOPROTEIN CD1D1, ... | | 著者 | Clarke, A.J, Le Nours, J, Rossjohn, J. | | 登録日 | 2012-04-05 | | 公開日 | 2013-04-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Type-II Natural Killer T Cell Antigen Receptor Mediated Recognition of Cd1D-Sulfatide
To be Published
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4L60
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4L6P
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1JPH
 | | Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | | 分子名称: | UROPORPHYRINOGEN DECARBOXYLASE | | 著者 | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | 登録日 | 2001-08-02 | | 公開日 | 2001-12-19 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
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6FZK
 | | NMR structure of UB2H, regulatory domain of PBP1b from E. coli | | 分子名称: | Penicillin-binding protein 1B | | 著者 | Simorre, J.P, Maya Martinez, R.C, Bougault, C, Egan, A.J.F, Vollmer, W. | | 登録日 | 2018-03-15 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Induced conformational changes activate the peptidoglycan synthase PBP1B.
Mol. Microbiol., 110, 2018
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