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1YSN
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Solution structure of the anti-apoptotic protein Bcl-xL complexed with an acyl-sulfonamide-based ligand
分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-X
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2023-11-29
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YX6
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Solution Structure of S5a UIM-2/Ubiquitin Complex
分子名称: 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin
著者Wang, Q, Young, P, Walters, K.J.
登録日2005-02-19
公開日2005-04-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of S5a Bound to Monoubiquitin Provides a Model for Polyubiquitin Recognition
J.Mol.Biol., 348, 2005
1XSC
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Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant) in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Bis(5'-nucleosyl)-tetraphosphatase
著者Swarbrick, J.D, Buyya, S, Gunawardana, D, Gayler, K.R, McLennan, A.G, Gooley, P.R.
登録日2004-10-18
公開日2004-12-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
J.Biol.Chem., 280, 2005
1YE3
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HORSE LIVER ALCOHOL DEHYDROGENASE APOENZYME
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Alcohol dehydrogenase E chain, ZINC ION
著者Plapp, B.V, Savarimuthu, B.R, Ramaswamy, S.
登録日2004-12-27
公開日2005-01-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Horse Liver Alcohol Dehydrogenase Apoenzyme
To be Published
1X6M
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Crystal structure of the glutathione-dependent formaldehyde-activating enzyme (Gfa)
分子名称: GLYCEROL, Glutathione-dependent formaldehyde-activating enzyme, SULFATE ION, ...
著者Neculai, A.M, Neculai, D, Vorholt, J.A, Becker, S.
登録日2004-08-11
公開日2004-11-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献A dynamic zinc redox switch
J.Biol.Chem., 280, 2005
1XSA
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Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)
分子名称: Bis(5'-nucleosyl)-tetraphosphatase
著者Swarbrick, J.D, Buyya, S, Gunawardana, D, Gayler, K.R, McLennan, A.G, Gooley, P.R.
登録日2004-10-18
公開日2004-12-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
J.Biol.Chem., 280, 2005
1XJS
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Solution structure of Iron-Sulfur cluster assembly protein IscU from Bacillus subtilis, with Zinc bound at the active site. Northeast Structural Genomics Consortium Target SR17
分子名称: NifU-like protein, ZINC ION
著者Kornhaber, G.J, Swapna, G.V.T, Ramelot, T.A, Cort, J.R, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2004-09-24
公開日2005-01-04
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Iron-Sulfur cluster assembly protein IscU from Bacillus subtilis, with Zinc bound at the active site. Northeast Structural Genomics Consortium Target SR17.
To be Published
1ZXJ
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Crystal structure of the hypthetical Mycoplasma protein, MPN555
分子名称: Hypothetical protein MG377 homolog
著者Schulze-Gahmen, U, Aono, S, Shengfeng, C, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2005-06-08
公開日2005-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.
Acta Crystallogr.,Sect.D, 61, 2005
1ZTR
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Solution structure of Engrailed homeodomain L16A mutant
分子名称: Segmentation polarity homeobox protein engrailed
著者Religa, T.L, Markson, J.S, Mayor, U, Freund, S.M.V, Fersht, A.R.
登録日2005-05-27
公開日2005-10-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of a protein denatured state and folding intermediate.
Nature, 437, 2005
1YGO
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Solution Structure of the pelle Death Domain
分子名称: Probable serine/threonine-protein kinase pelle
著者Moncrieffe, M.C, Stott, K.M, Gay, N.J.
登録日2005-01-05
公開日2005-07-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the isolated Pelle death domain.
Febs Lett., 579, 2005
1YG3
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Solution Structure of the ScYLV P1-P2 Frameshifting Pseudoknot, 20 Lowest Energy Structures
分子名称: ScYLV RNA pseudoknot
著者Cornish, P.V, Hennig, M, Giedroc, D.P.
登録日2005-01-04
公開日2005-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A loop 2 cytidine-stem 1 minor groove interaction as a positive determinant for pseudoknot-stimulated -1 ribosomal frameshifting
Proc.Natl.Acad.Sci.USA, 102, 2005
2A55
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Solution structure of the two N-terminal CCP modules of C4b-binding protein (C4BP) alpha-chain.
分子名称: C4b-binding protein
著者Jenkins, H.T, Mark, L, Ball, G, Lindahl, G, Uhrin, D, Blom, A.M, Barlow, P.N.
登録日2005-06-30
公開日2005-12-13
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Human C4b-binding Protein, Structural Basis for Interaction with Streptococcal M Protein, a Major Bacterial Virulence Factor
J.Biol.Chem., 281, 2006
2A1C
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Solution structure of CSP1
分子名称: CSP1
著者Johnsborg, O, Kristiansen, P.E.
登録日2005-06-20
公開日2006-05-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A Hydrophobic Patch in the Pneumococcal Competence Pheromone CSP is Essential for Specificity and Biological Activity
To be Published
1YSW
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Solution structure of the anti-apoptotic protein Bcl-2 complexed with an acyl-sulfonamide-based ligand
分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-09
公開日2005-06-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YSI
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Solution structure of the anti-apoptotic protein Bcl-xL in complex with an acyl-sulfonamide-based ligand
分子名称: Apoptosis regulator Bcl-X, N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITRO-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-08
公開日2005-06-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
1YR1
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Structure of the major extracytoplasmic domain of the trans isomer of the bacterial cell division protein divib from geobacillus stearothermophilus
分子名称: cell-division initiation protein
著者Robson, S.A, King, G.F.
登録日2005-02-02
公開日2006-02-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Domain architecture and structure of the bacterial cell division protein DivIB.
Proc.Natl.Acad.Sci.USA, 103, 2006
1YSX
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Solution structure of domain 3 from human serum albumin complexed to an anti-apoptotic ligand directed against Bcl-xL and Bcl-2
分子名称: 4-({2-[(2,4-DIMETHYLPHENYL)SULFANYL]ETHYL}AMINO)-N-[(4'-FLUORO-1,1'-BIPHENYL-4-YL)CARBONYL]-3-NITROBENZENESULFONAMIDE, Serum albumin
著者Oltersdorf, T, Elmore, S.W, Shoemaker, A.R, Armstrong, R.C, Augeri, D.J, Belli, B.A, Bruncko, M, Deckwerth, T.L, Dinges, J, Hajduk, P.J, Joseph, M.K, Kitada, S, Korsmeyer, S.J, Kunzer, A.R, Letai, A, Li, C, Mitten, M.J, Nettesheim, D.G, Ng, S, Nimmer, P.M, O'Connor, J.M, Oleksijew, A, Petros, A.M, Reed, J.C, Shen, W, Tahir, S.K, Thompson, C.B, Tomaselli, K.J, Wang, B, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H.
登録日2005-02-09
公開日2005-06-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Nature, 435, 2005
230D
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SOLUTION STRUCTURES OF UNIMOLECULAR QUADRUPLEXES FORMED BY OLIGONUCLEOTIDES CONTAINING OXYTRICHA TELOMERE REPEATS
分子名称: QUADRUPLEXES DNA
著者Smith, F.W, Schultze, P, Feigon, J.
登録日1995-08-24
公開日1995-10-15
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structures of unimolecular quadruplexes formed by oligonucleotides containing Oxytricha telomere repeats.
Structure, 3, 1995
1XSB
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Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant) in complex with ATP. No ATP restraints included
分子名称: Bis(5'-nucleosyl)-tetraphosphatase
著者Swarbrick, J.D, Buyya, S, Gunawardana, D, Gayler, K.R, McLennan, A.G, Gooley, P.R.
登録日2004-10-18
公開日2004-12-21
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and Substrate-binding Mechanism of Human Ap4A Hydrolase
J.Biol.Chem., 280, 2005
1Y9H
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Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement
分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, 5'-D(*CP*CP*AP*TP*(5CM)P*(BPG)P*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*CP*GP*AP*TP*GP*G)-3'
著者Zhang, N, Lin, C, Huang, X, Kolbanovskiy, A, Hingerty, B.E, Amin, S, Broyde, S, Geacintov, N.E, Patel, D.J.
登録日2004-12-15
公開日2005-03-22
最終更新日2024-04-24
実験手法SOLUTION NMR
主引用文献Methylation of cytosine at C5 in a CpG sequence context causes a conformational switch of a benzo[a]pyrene diol epoxide-N2-guanine adduct in DNA from a minor groove alignment to intercalation with base displacement.
J.Mol.Biol., 346, 2005
1YBR
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Solution structure of the 5'E topology of the i-motif tetramer of d(CCCCAA)
分子名称: 5'-D(*CP*CP*CP*CP*AP*A)-3'
著者Esmaili, N, Leroy, J.-L.
登録日2004-12-21
公開日2005-01-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献i-motif solution structure and dynamics of the d(AACCCC) and d(CCCCAA) tetrahymena telomeric repeats
Nucleic Acids Res., 33, 2005
1YWS
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Solution structure of YBL071w-A from Saccharomyces cerevisiae.
分子名称: ZINC ION, protein YBL071w-A
著者Lukin, J.A, Guido, V, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG)
登録日2005-02-18
公開日2005-03-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of YBL071w-A from Saccharomyces cerevisiae
To be published
1YX4
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Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
分子名称: 26S proteasome non-ATPase regulatory subunit 4
著者Wang, Q, Young, P, Walters, K.J.
登録日2005-02-19
公開日2005-04-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of S5a bound to monoubiquitin provides a model for polyubiquitin recognition
J.Mol.Biol., 348, 2005
1YYX
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The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) at 2.8M urea
分子名称: Redesigned apo-cytochrome b562
著者Feng, H, Vu, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
登録日2005-02-25
公開日2005-08-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Detection and structure determination of an equilibrium unfolding intermediates of Rd-apocytochrome b562: native fold with non-native hydrophobic interactions
J.Mol.Biol., 343, 2004
1YWX
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Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16
分子名称: 30S ribosomal protein S24e
著者Yang, C.S, Acton, T, Shen, Y, Ma, L, Liu, G, Xiao, R, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2005-02-18
公開日2005-04-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of Methanococcus maripaludis Protein MMP0443: The Northeast Structural Genomics Consortium Target MrR16
To be Published

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