8PFU
 
 | | X-ray structure of the adduct formed upon reaction of Lysozyme with K3[Ru2(CO3)4] in condition A | | 分子名称: | 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CARBONATE ION, Lysozyme C, ... | | 著者 | Teran, A, Ferraro, G, Merlino, A. | | 登録日 | 2023-06-16 | | 公開日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
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8PFT
 | | X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition A | | 分子名称: | 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CHLORIDE ION, Lysozyme C, ... | | 著者 | Teran, A, Ferraro, G, Merlino, A. | | 登録日 | 2023-06-16 | | 公開日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (1.304 Å) | | 主引用文献 | Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
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8PFW
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8PFX
 | | X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition B | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, FORMIC ACID, ... | | 著者 | Teran, A, Ferraro, G, Merlino, A. | | 登録日 | 2023-06-16 | | 公開日 | 2023-07-19 | | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | | 主引用文献 | Charge effect in protein metalation reactions by diruthenium complexes
Inorg Chem Front, 2023
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8PEW
 | | Rho-ATPgS-Psu complex II | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Rho-ATPgS-Psu complex II
To Be Published
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8PEX
 | | Rho P167L-ATPgS-Psu complex I | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Rho P167L-ATPgS-Psu complex I
To Be Published
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8PEU
 | | Rho-ATPgS-Psu complex I | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Rho-ATPgS-Psu complex I
To Be Published
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8PEY
 | | Rho P167L-ATPgS-Psu complex II | | 分子名称: | MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Polarity suppression protein, ... | | 著者 | Gjorgjevikj, D, Wahl, M.C, Hilal, T, Loll, B. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Rho P167L-ATPgS-Psu complex II
To Be Published
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8JQV
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8T6D
 | | Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors | | 分子名称: | (3R)-1'-[3-(3,4-dihydro-1,5-naphthyridin-1(2H)-yl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-3H-spiro[[1]benzofuran-2,4'-piperidin]-3-amine, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Tang, Y, Nguyen, V, Wilbur, J.D. | | 登録日 | 2023-06-15 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.
J.Med.Chem., 66, 2023
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8T6G
 | | Identification of GDC-1971 (RLY-1971), a SHP2 inhibitor designed for the treatment of solid tumors | | 分子名称: | (1S)-1-{6-[(1S)-1-amino-1,3-dihydrospiro[indene-2,4'-piperidin]-1'-yl]-3-(3,4-dihydro-1,5-naphthyridin-1(2H)-yl)-1H-pyrazolo[3,4-b]pyrazin-5-yl}ethan-1-ol, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Tang, Y, Nugyen, V, Wilbur, J.D. | | 登録日 | 2023-06-15 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.
J.Med.Chem., 66, 2023
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8JR0
 | | Cryo-EM structure of Mycobacterium tuberculosis ATP synthase in complex with TBAJ-587 | | 分子名称: | (1~{S},2~{S})-1-(6-bromanyl-2-methoxy-quinolin-3-yl)-2-(2,6-dimethoxypyridin-4-yl)-4-(dimethylamino)-1-(2-fluoranyl-3-methoxy-phenyl)butan-2-ol, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhang, Y, Lai, Y, Liu, F, Rao, Z, Gong, H. | | 登録日 | 2023-06-15 | | 公開日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structure of Mycobacterium tuberculosis ATP synthase
To Be Published
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8PEQ
 | | Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) | | 分子名称: | Affilin variant Af2, Fibronectin, SULFATE ION | | 著者 | Parthier, C, Katzschmann, A, Fiedler, E, Haupts, U, Reimann, A. | | 登録日 | 2023-06-14 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage
to be published
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8JQU
 | | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | Pandey, D, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A. | | 登録日 | 2023-06-14 | | 公開日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | | 主引用文献 | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani
To Be Published
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8T5U
 | | ATP-1 state of Bcs1 (C7 symmetrized) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | | 著者 | Zhan, J, Xia, D. | | 登録日 | 2023-06-14 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
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8PEE
 | | ABCB1 L335C mutant (mABCB1) in the inward facing state bound to AAC | | 分子名称: | (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1, ... | | 著者 | Parey, K, Januliene, D, Gewering, T, Moeller, A. | | 登録日 | 2023-06-13 | | 公開日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Tracing the substrate translocation mechanism in P-glycoprotein.
Elife, 12, 2024
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8JPY
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8JQ1
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8PD8
 | | cAMP-bound SpSLC9C1 in lipid nanodiscs, dimer | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | 著者 | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | 登録日 | 2023-06-12 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PD9
 | | cAMP-bound SpSLC9C1 in lipid nanodiscs, protomer state 1 | | 分子名称: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | 著者 | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | 登録日 | 2023-06-12 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PDV
 | | cGMP-bound SpSLC9C1 in lipid nanodiscs, protomer | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | 著者 | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | 登録日 | 2023-06-12 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | | 主引用文献 | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PDU
 | | cGMP-bound SpSLC9C1 in lipid nanodiscs, dimer | | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Sperm-specific sodium proton exchanger | | 著者 | Kalienkova, V, Peter, M, Rheinberger, J, Paulino, C. | | 登録日 | 2023-06-12 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structures of a sperm-specific solute carrier gated by voltage and cAMP.
Nature, 623, 2023
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8PDC
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8JPP
 | | Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y. | | 登録日 | 2023-06-12 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
Cell Res., 2024
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8JPN
 | | Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi | | 分子名称: | (2R,3S)-oxirane-2,3-dicarboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Wang, T.X, Tang, W.Q, Li, F.H, Wang, J.Y. | | 登録日 | 2023-06-12 | | 公開日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
Cell Res., 2024
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