2E0J
 
 | | Mutant Human Ribonuclease 1 (R31L, R32L) | | 分子名称: | Ribonuclease | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
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2Q1D
 | | 2-keto-3-deoxy-D-arabinonate dehydratase complexed with magnesium and 2,5-dioxopentanoate | | 分子名称: | 2,5-DIOXOPENTANOIC ACID, 2-keto-3-deoxy-D-arabinonate dehydratase, MAGNESIUM ION | | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | | 登録日 | 2007-05-24 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol., 379, 2008
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3C4O
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M/S130K/S146M complex | | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | 著者 | Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M. | | 登録日 | 2008-01-30 | | 公開日 | 2008-05-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
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4AL1
 | | Crystal structure of Human PS-1 GSH-analog complex | | 分子名称: | L-gamma-glutamyl-S-(2-biphenyl-4-yl-2-oxoethyl)-L-cysteinylglycine, PALMITIC ACID, PROSTAGLANDIN E SYNTHASE, ... | | 著者 | Sjogren, T, Nord, J, Ek, M, Johansson, P, Liu, G, Geschwindner, S. | | 登録日 | 2012-02-29 | | 公開日 | 2013-02-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of Microsomal Prostaglandin E2 Synthase Provides Insight Into Diversity in the Mapeg Superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3C4P
 | | Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) E73M complex | | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein, SULFATE ION | | 著者 | Reynolds, K.A, Hanes, M.S, Thomson, J.M, Antczak, A.J, Berger, J.M, Bonomo, R.A, Kirsch, J.F, Handel, T.M. | | 登録日 | 2008-01-30 | | 公開日 | 2008-05-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Computational redesign of the SHV-1 beta-lactamase/beta-lactamase inhibitor protein interface.
J.Mol.Biol., 382, 2008
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2Q1C
 | | 2-keto-3-deoxy-D-arabinonate dehydratase complexed with calcium and 2-oxobutyrate | | 分子名称: | 2-KETOBUTYRIC ACID, 2-keto-3-deoxy-D-arabinonate dehydratase, CALCIUM ION | | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | | 登録日 | 2007-05-24 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol., 379, 2008
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2Q19
 | | 2-keto-3-deoxy-D-arabinonate dehydratase apo form | | 分子名称: | 2-keto-3-deoxy-D-arabinonate dehydratase | | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | | 登録日 | 2007-05-24 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol., 379, 2008
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4P65
 | | Crystal structure of an cyclohexylalanine substituted insulin analog. | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Pandyarajan, V, Wan, Z, Weiss, M.A. | | 登録日 | 2014-03-21 | | 公開日 | 2014-10-22 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Aromatic Anchor at an Invariant Hormone-Receptor Interface: FUNCTION OF INSULIN RESIDUE B24 WITH APPLICATION TO PROTEIN DESIGN.
J.Biol.Chem., 289, 2014
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1QSM
 | | Histone Acetyltransferase HPA2 from Saccharomyces Cerevisiae in Complex with Acetyl Coenzyme A | | 分子名称: | ACETYL COENZYME *A, HPA2 HISTONE ACETYLTRANSFERASE | | 著者 | Angus-Hill, M.L, Dutnall, R.N, Tafrov, S.T, Sternglanz, R, Ramakrishnan, V. | | 登録日 | 1999-06-22 | | 公開日 | 1999-12-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily.
J.Mol.Biol., 294, 1999
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1FWK
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE COMPLEXED WITH ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, HOMOSERINE KINASE, MAGNESIUM ION | | 著者 | Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. | | 登録日 | 2000-09-22 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
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2Q1A
 | | 2-keto-3-deoxy-D-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate | | 分子名称: | 2-KETOBUTYRIC ACID, 2-keto-3-deoxy-D-arabinonate dehydratase, MAGNESIUM ION | | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | | 登録日 | 2007-05-24 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol., 379, 2008
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1FWL
 | | CRYSTAL STRUCTURE OF HOMOSERINE KINASE | | 分子名称: | HOMOSERINE KINASE | | 著者 | Zhou, T, Daugherty, M, Grishin, N.V, Osterman, A.L, Zhang, H. | | 登録日 | 2000-09-22 | | 公開日 | 2000-12-20 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily.
Structure Fold.Des., 8, 2000
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5DC4
 | | CRYSTAL STRUCTURE OF MONOBODY AS25/ABL1 SH2 DOMAIN COMPLEX, CRYSTAL A | | 分子名称: | AS25 monobody, GLYCEROL, Tyrosine-protein kinase ABL1 | | 著者 | Wojcik, J.B, Koide, A, Koide, S. | | 登録日 | 2015-08-23 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
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2Q18
 | | 2-keto-3-deoxy-D-arabinonate dehydratase | | 分子名称: | 2-keto-3-deoxy-D-arabinonate dehydratase, PHOSPHATE ION | | 著者 | Barends, T, Brouns, S, Worm, P, Akerboom, J, Turnbull, A, Salmon, L. | | 登録日 | 2007-05-24 | | 公開日 | 2008-04-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
J.Mol.Biol., 379, 2008
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1QSO
 | | Histone Acetyltransferase HPA2 from Saccharomyces Cerevisiae | | 分子名称: | HPA2 HISTONE ACETYLTRANSFERASE | | 著者 | Angus-Hill, M.L, Dutnall, R.N, Tafrov, S.T, Sterngalnz, R, Ramakrishnan, V. | | 登録日 | 1999-06-22 | | 公開日 | 1999-12-22 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily.
J.Mol.Biol., 294, 1999
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2QBW
 | | The crystal structure of PDZ-Fibronectin fusion protein | | 分子名称: | PDZ-Fibronectin fusion protein, Polypeptide | | 著者 | Huang, J, Makabe, K, Koide, A, Koide, S. | | 登録日 | 2007-06-18 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Design of protein function leaps by directed domain interface evolution.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2E0O
 | | Mutant Human Ribonuclease 1 (V52L, D53L, N56L, F59L) | | 分子名称: | GLYCEROL, Ribonuclease, SULFATE ION | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
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2E0L
 | | Mutant Human Ribonuclease 1 (Q28L, R31L, R32L) | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ribonuclease | | 著者 | Yamada, H, Tamada, T, Kosaka, M, Kuroki, R. | | 登録日 | 2006-10-10 | | 公開日 | 2007-08-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines
Protein Sci., 16, 2007
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3LOM
 | | CRYSTAL STRUCTURE OF GERANYLTRANSFERASE FROM Legionella pneumophila | | 分子名称: | Geranyltranstransferase, PHOSPHATE ION | | 著者 | Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2010-02-04 | | 公開日 | 2010-02-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
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5DA1
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3EA3
 | | Crystal Structure of the Y246S/Y247S/Y248S/Y251S Mutant of Phosphatidylinositol-Specific Phospholipase C from Bacillus Thuringiensis | | 分子名称: | 1-phosphatidylinositol phosphodiesterase, MANGANESE (II) ION | | 著者 | Shi, X, Shao, C, Zhang, X, Zambonelli, C, Redfied, A.G, Head, J.F, Seaton, B.A, Roberts, M.F. | | 登録日 | 2008-08-24 | | 公開日 | 2009-04-14 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Modulation of Bacillus thuringiensis Phosphatidylinositol-specific Phospholipase C Activity by Mutations in the Putative Dimerization Interface.
J.Biol.Chem., 284, 2009
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4TXD
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5H9B
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1N8E
 | | Fragment Double-D from Human Fibrin | | 分子名称: | Fibrin alpha/alpha-E chain, Fibrin beta chain, Fibrin gamma chain | | 著者 | Yang, Z, Pandi, L, Doolittle, R.F. | | 登録日 | 2002-11-20 | | 公開日 | 2003-01-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | The Crystal Structure of Fragment Double-D from Cross-Linked Lamprey Fibrin Reveals Isopeptide Linkages across an Unexpected D-D Interface
Biochemistry, 41, 2002
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4UYN
 | | SAR156497 an exquisitely selective inhibitor of Aurora kinases | | 分子名称: | AURORA KINASE A, ethyl (9S)-9-[5-(1H-benzimidazol-2-ylsulfanyl)furan-2-yl]-8-hydroxy-5,6,7,9-tetrahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | | 著者 | Carry, J.C, Clerc, F, Minoux, H, Schio, L, Mauger, J, Nair, A, Parmantier, E, Lemoigne, R, Delorme, C, Nicolas, J.P, Krick, A, Abecassis, P.Y, Crocq-Stuerga, V, Pouzieux, S, Delarbre, L, Maignan, S, Bertrand, T, Bjergarde, K, Ma, N, Lachaud, S, Guizani, H, Lebel, R, Doerflinger, G, Monget, S, Perron, S, Gasse, F, Angouillant-Boniface, O, Filoche-Romme, B, Murer, M, Gontier, S, Prevost, C, Monteiro, M.L, Combeau, C. | | 登録日 | 2014-09-02 | | 公開日 | 2014-11-19 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Sar156497, an Exquisitely Selective Inhibitor of Aurora Kinases.
J.Med.Chem., 58, 2015
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