PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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6OLE	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OKP	B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 分子名称: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2019-04-14 公開日 2019-06-05 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
6OLF	Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-16 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
8G5Z	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.64 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G6J	mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) 分子名称: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-15 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8G5Y	mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.29 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8GHU	Methyltransferase RmtC bound to the 30S ribosomal subunit 分子名称: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ... 著者 Srinivas, P, Conn, G.L, Dunham, C.M. 登録日 2023-03-12 公開日 2023-04-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Biorxiv, 2023
4OSL	Crystal structure of TAL effector reveals the recognition between histidine and guanine 分子名称: DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*CP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, ... 著者 Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. 登録日 2014-02-13 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.447 Å) 主引用文献 Revisiting the TALE repeat Protein Cell, 5, 2014
8G60	mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) 分子名称: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... 著者 Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. 登録日 2023-02-14 公開日 2023-04-19 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
8FL2	Human nuclear pre-60S ribosomal subunit (State I1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.67 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL4	Human nuclear pre-60S ribosomal subunit (State I3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL6	Human nuclear pre-60S ribosomal subunit (State J1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLC	Human nuclear pre-60S ribosomal subunit (State K3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.76 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FKZ	Human nucleolar pre-60S ribosomal subunit (State G) 分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FLD	Human nuclear pre-60S ribosomal subunit (State L1) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.58 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FL7	Human nuclear pre-60S ribosomal subunit (State J2) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-26 実験手法 ELECTRON MICROSCOPY (2.55 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
4OSM	Crystal structure of the S505H mutant of TAL effector dHax3 分子名称: DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 著者 Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. 登録日 2014-02-13 公開日 2014-05-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.454 Å) 主引用文献 Revisiting the TALE repeat Protein Cell, 5, 2014
6OM7	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-18 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6OY7	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2019-05-14 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.04 Å) 主引用文献 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020
6OLZ	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
6BOK	E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2017-11-20 公開日 2018-05-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Conformational Control of Translation Termination on the 70S Ribosome. Structure, 26, 2018
6ENU	Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P) 分子名称: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Huter, P, Arenz, S, Wilson, D.N. 登録日 2017-10-06 公開日 2017-11-22 最終更新日 2018-01-31 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P. Mol. Cell, 68, 2017
8G4L	Cryo-EM structure of the human cardiac myosin filament 分子名称: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ... 著者 Dutta, D, Nguyen, V, Padron, R, Craig, R. 登録日 2023-02-10 公開日 2023-11-01 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Cryo-EM structure of the human cardiac myosin filament. Nature, 623, 2023
3UMW	Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one 分子名称: (2Z)-2-(1H-indazol-3-ylmethylidene)-6-methoxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3(2H)-one, GLYCEROL, Proto-oncogene serine/threonine-protein kinase pim-1, ... 著者 Parker, L.J, Handa, N, Yokoyama, S. 登録日 2011-11-14 公開日 2012-10-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound. J.Med.Chem., 55, 2012
6OVY	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2019-05-08 公開日 2019-07-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.999 Å) 主引用文献 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase. Nucleic Acids Res., 48, 2020

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