PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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7OAG	Cryo-EM structure of the plectasin fibril (single strand) 分子名称: Fungal defensin plectasin 著者 Effantin, G. 登録日 2021-04-19 公開日 2022-04-27 最終更新日 2022-11-16 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 pH- and concentration-dependent supramolecular assembly of a fungal defensin plectasin variant into helical non-amyloid fibrils. Nat Commun, 13, 2022
5K6Z	Sidekick chimera containing sidekick-2 immunoglobulin domains 1-2 and sidekick-1 immunoglobulin domains 3-4 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. 登録日 2016-05-25 公開日 2016-09-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
5G5V	Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-038 分子名称: (4AS,8AR)-4-(3-{4-[(3R)-3-HYDROXYPYRROLIDINE-1-, 1,2-ETHANEDIOL, FORMIC ACID, ... 著者 Singh, A.K, Brown, D.G. 登録日 2016-06-06 公開日 2018-03-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. J. Med. Chem., 61, 2018
5G40	Crystal structure of adenylate kinase ancestor 4 with Zn and AMP-ADP bound 分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINSE, ... 著者 Nguyen, V, Kutter, S, English, J, Kern, D. 登録日 2016-05-03 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Evolutionary drivers of thermoadaptation in enzyme catalysis. Science, 355, 2017
5FAX	Structure of subtilase SubHal from Bacillus halmapalus 分子名称: CALCIUM ION, Subtilase SubHal from Bacillus halmapalus 著者 Dohnalek, J, Brzozowski, A.M, Svendsen, A, Wilson, K.S. 登録日 2015-12-12 公開日 2016-05-18 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Stabilization of Enzymes by Metal Binding: Structures of Two Alkalophilic Bacillus Subtilases and Analysis of the Second Metal-Binding Site of the Subtilase Family Book, 2016
5G0S	InhA in complex with a DNA encoded library hit 分子名称: ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], N-[4-[2-[(2S)-4-[2-(methylamino)-2-oxidanylidene-ethyl]-3-oxidanylidene-2-(phenylmethyl)piperazin-1-yl]-2-oxidanylidene-ethyl]cyclohexyl]-2-(3-methyl-1-benzothiophen-2-yl)ethanamide, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Read, J.A, Breed, J. 登録日 2016-03-22 公開日 2016-11-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
7OJ2	Bacillus subtilis IMPDH in complex with Ap4A 分子名称: GLYCEROL, Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase, PHOSPHATE ION 著者 Giammarinaro, P.I, Bange, G. 登録日 2021-05-13 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
7OJ1	Bacillus subtilis IMPDH in complex with Ap4A 分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Inosine-5'-monophosphate dehydrogenase, MAGNESIUM ION 著者 Giammarinaro, P.I, Bange, G. 登録日 2021-05-13 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Diadenosine tetraphosphate regulates biosynthesis of GTP in Bacillus subtilis. Nat Microbiol, 7, 2022
7NXX	Structure of Superoxide Dismutase 1 (SOD1) in complex with nanobody 2 (Nb2). 分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION, ... 著者 Gallardo, R, Rousseau, F, Schymkowitz, J, Ulens, C. 登録日 2021-03-19 公開日 2022-09-28 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.189 Å) 主引用文献 Identification and rational improvement of a nanobody that suppresses aggregation of mutant SOD1 To Be Published
5ESP	Crystal Structure of LAGLIDADG Meganuclease I-PanMI with coordinated Calcium ions 分子名称: CALCIUM ION, DNA (27-MER), GLYCEROL, ... 著者 Hallinan, J.P, Stoddard, B.L. 登録日 2015-11-16 公開日 2016-03-30 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.995 Å) 主引用文献 Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure, 24, 2016
5K6W	Sidekick-1 immunoglobulin domains 1-5 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. 登録日 2016-05-25 公開日 2016-09-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
2YQ8	Crystal structure of the SeMet-labeled N-terminal domain and peptide substrate binding domain of alpha subunit of prolyl-4 hydroxylase type I from human. 分子名称: PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 著者 Anantharajan, J, Koski, M.K, Wierenga, R.K. 登録日 2012-11-06 公開日 2013-10-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 The Structural Motifs for Substrate Binding and Dimerization of the Alpha Subunit of Collagen Prolyl 4-Hydroxylase Structure, 21, 2013
5F3I	Crystal structure of human KDM4A in complex with compound 54j 分子名称: 8-[4-[2-[4-[3,5-bis(chloranyl)phenyl]piperidin-1-yl]ethyl]pyrazol-1-yl]-3~{H}-pyrido[3,4-d]pyrimidin-4-one, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Le Bihan, Y.-V, Dempster, S, Westwood, I.M, van Montfort, R.L.M. 登録日 2015-12-02 公開日 2016-01-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
5F5C	Crystal Structure of human JMJD2D complexed with KDOPP7 分子名称: 1,2-ETHANEDIOL, 8-[[(phenylmethyl)amino]methyl]-1~{H}-pyrido[3,4-d]pyrimidin-4-one, Lysine-specific demethylase 4D, ... 著者 Krojer, T, Vollmar, M, Crawley, L, Bradley, A.R, Szykowska, A, Ruda, G.F, Yang, H, Burgess-Brown, N, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U, von Delft, F, Structural Genomics Consortium (SGC) 登録日 2015-12-04 公開日 2015-12-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors. J.Med.Chem., 59, 2016
5KHQ	Rasip1 RA domain 分子名称: GLYCEROL, Ras-interacting protein 1 著者 Gingras, A.R. 登録日 2016-06-15 公開日 2016-10-19 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins. Structure, 24, 2016
2YHT	Crystal structure of Hfq riboregulator from E. coli (P1 space group) 分子名称: PROTEIN HFQ 著者 Basquin, J, Sauter, C. 登録日 2011-05-06 公開日 2011-11-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Exploiting Protein Engineering and Crystal Polymorphism for Successful X-Ray Structure Determination Cryst.Growth Des., 11, 2011
5GVP	Plasmodium vivax SHMT bound with PLP-glycine and GS654 分子名称: 3-[3-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]phenyl]propanoic acid, CHLORIDE ION, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... 著者 Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U, Schwertz, G. 登録日 2016-09-06 公開日 2017-07-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures J. Med. Chem., 60, 2017
2BMW	Ferredoxin: NADP+ Reductase Mutant With Thr 155 Replaced By Gly, Ala 160 Replaced By Thr, Leu 263 Replaced By Pro, Arg 264 Replaced By Pro and Gly 265 Replaced by Pro (T155G-A160T-L263P-R264P-G265P) 分子名称: FERREDOXIN--NADP REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION 著者 Martinez-Julvez, M, Hermoso, J.A, Perez-Dorado, I, Medina, M, Tejero, J, Gomez-Moreno, C. 登録日 2005-03-16 公開日 2006-06-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Protein Motifs Involved in Coenzyme Interaction and Enzymatic Efficiency in Anabaena Ferredoxin-Nadp+ Reductase. Biochemistry, 48, 2009
5GKO	Crystal structure of tripartite-type ABC transporter, MacB from Acinetobacter baumannii 分子名称: Macrolide export ATP-binding/permease protein MacB 著者 Murakami, S, Okada, U, Yamashita, E. 登録日 2016-07-04 公開日 2017-11-15 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (3.393 Å) 主引用文献 Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii. Nat Commun, 8, 2017
2Y7G	Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the product acetoacetate 分子名称: 3-KETO-5-AMINOHEXANOATE CLEAVAGE ENZYME, ACETOACETIC ACID, GLYCEROL, ... 著者 Bellinzoni, M, Alzari, P.M. 登録日 2011-01-31 公開日 2011-06-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 3-Keto-5-Aminohexanoate Cleavage Enzyme: A Common Fold for an Uncommon Claisen-Type Condensation. J.Biol.Chem., 286, 2011
3BDM	yeast 20S proteasome:glidobactin A-complex 分子名称: (2E,4E)-N-[(2S,3R)-3-hydroxy-1-[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]-1-ox obutan-2-yl]dodeca-2,4-dienamide, Proteasome component C1, Proteasome component C11, ... 著者 Groll, M, Dudler, R, Kaiser, M. 登録日 2007-11-15 公開日 2008-04-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism Nature, 452, 2008
5K70	Sidekick-2 immunoglobulin domains 1-4 H18R/N22S mutant 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, ... 著者 Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. 登録日 2016-05-25 公開日 2016-09-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis of sidekick-mediated cell-cell adhesion and specificity. Elife, 5, 2016
5JOP	Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A 分子名称: Fab 14.22 light chain, Fab14.22 heavy chain, GLYCEROL, ... 著者 Sarkar, A, Irimia, A, Teyton, L, Wilson, I.A. 登録日 2016-05-02 公開日 2017-03-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 T cells control the generation of nanomolar-affinity anti-glycan antibodies. J. Clin. Invest., 127, 2017
5FC4	Mcl-1 complexed with small molecule inhibitor 分子名称: 2-[5-[1,1,2,2-tetrakis(fluoranyl)ethyl]-1~{H}-pyrazol-3-yl]phenol, 6-chloranyl-~{N}-methylsulfonyl-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indole-2-carboxamide, Induced myeloid leukemia cell differentiation protein Mcl-1 著者 Zhao, B. 登録日 2015-12-14 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods. J.Med.Chem., 59, 2016
3BHO	Crystal Structure of the 25kDa Subunit of Human Cleavage factor Im with Ap4A 分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, Cleavage and polyadenylation specificity factor subunit 5 著者 Coseno, M, Doublie, S. 登録日 2007-11-28 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the 25 kDa subunit of human cleavage factor Im. Nucleic Acids Res., 36, 2008

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