1R0E
 
 | | Glycogen synthase kinase-3 beta in complex with 3-indolyl-4-arylmaleimide inhibitor | | 分子名称: | 3-[3-(2,3-DIHYDROXY-PROPYLAMINO)-PHENYL]-4-(5-FLUORO-1-METHYL-1H-INDOL-3-YL)-PYRROLE-2,5-DIONE, CITRATE ANION, Glycogen synthase kinase-3 beta | | 著者 | Allard, J, Nikolcheva, T, Gong, L, Wang, J, Dunten, P, Avnur, Z, Waters, R, Sun, Q, Skinner, B. | | 登録日 | 2003-09-20 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | From genetics to therapeutics: the Wnt pathway and osteoporosis
To be Published
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2LF8
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1R36
 | | NMR-based structure of autoinhibited murine Ets-1 deltaN301 | | 分子名称: | C-ets-1 protein | | 著者 | Lee, G.M, Donaldson, L.W, Pufall, M.A, Kang, H.-S, Pot, I, Graves, B.J, McIntosh, L.P. | | 登録日 | 2003-09-30 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The Structural and Dynamic Basis of Ets-1 DNA Binding Autoinhibition
J.Biol.Chem., 280, 2005
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1SDY
 | | STRUCTURE SOLUTION AND MOLECULAR DYNAMICS REFINEMENT OF THE YEAST CU,ZN ENZYME SUPEROXIDE DISMUTASE | | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | | 著者 | Djinovic, K, Gatti, G, Coda, A, Antolini, L, Pelosi, G, Desideri, A, Falconi, M, Marmocchi, F, Rotilio, G, Bolognesi, M. | | 登録日 | 1991-06-14 | | 公開日 | 1994-01-31 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure solution and molecular dynamics refinement of the yeast Cu,Zn enzyme superoxide dismutase.
Acta Crystallogr.,Sect.B, 47, 1991
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1SHK
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2ME6
 | | NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG | | 分子名称: | DNA (5'-D(*CP*GP*AP*CP*TP*AP*AP*TP*TP*AP*GP*TP*CP*G)-3'), Homeobox protein GBX-1 | | 著者 | Proudfoot, A, Serrano, P, Geralt, M, Wuthrich, K, Joint Center for Structural Genomics (JCSG), Partnership for Stem Cell Biology (STEMCELL) | | 登録日 | 2013-09-23 | | 公開日 | 2013-10-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure of the homeodomain transcription factor Gbx1 from Homo sapiens in complex with the DNA sequence CGACTAATTAGTCG
To be Published
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2MGQ
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2M34
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2MD5
 | | Structure of uninhibited ETV6 ETS domain | | 分子名称: | Transcription factor ETV6 | | 著者 | De, S, Mcintosh, L.P, Chan, A.C, Coyne, H.J, Okon, M, Graves, B.J, Murphy, M.E. | | 登録日 | 2013-08-29 | | 公開日 | 2013-12-25 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6.
J.Mol.Biol., 426, 2014
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1RG8
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2ME0
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1Q04
 | | Crystal structure of FGF-1, S50E/V51N | | 分子名称: | FORMIC ACID, Heparin-binding growth factor 1 | | 著者 | Kim, J, Blaber, M. | | 登録日 | 2003-07-15 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
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1PPG
 | | The refined 2.3 angstroms crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor | | 分子名称: | HUMAN LEUKOCYTE ELASTASE, MEO-SUCCINYL-ALA-ALA-PRO-VAL CHLOROMETHYLKETONE, alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Bode, W, Wei, A-Z. | | 登録日 | 1991-10-24 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The refined 2.3 A crystal structure of human leukocyte elastase in a complex with a valine chloromethyl ketone inhibitor.
FEBS Lett., 234, 1988
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2M9U
 | | Solution NMR structure of the C-terminal domain (CTD) of Moloney murine leukemia virus integrase, Northeast Structural Genomics Target OR41A | | 分子名称: | Integrase p46 | | 著者 | Aiyer, S, Rossi, P, Schneider, W.M, Chander, A, Roth, M.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2013-06-19 | | 公開日 | 2013-12-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction.
Nucleic Acids Res., 42, 2014
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1PYX
 | | GSK-3 Beta complexed with AMP-PNP | | 分子名称: | Glycogen synthase kinase-3 beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. | | 登録日 | 2003-07-09 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors
J.Mol.Biol., 333, 2003
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1Q03
 | | Crystal structure of FGF-1, S50G/V51G mutant | | 分子名称: | Heparin-binding growth factor 1 | | 著者 | Kim, J, Blaber, M. | | 登録日 | 2003-07-15 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
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1PXK
 | | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR N-[4-(2,4-Dimethyl-thiazol-5-yl)pyrimidin-2-yl]-N'-hydroxyiminoformamide | | 分子名称: | Cell division protein kinase 2, N-[4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)PYRIMIDIN-2-YL]-N'-HYDROXYIMIDOFORMAMIDE | | 著者 | Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. | | 登録日 | 2003-07-04 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop
Structure, 11, 2003
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2MWA
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2MWF
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1Q3D
 | | GSK-3 Beta complexed with Staurosporine | | 分子名称: | GLYCOGEN SYNTHASE KINASE-3 BETA, STAUROSPORINE | | 著者 | Bertrand, J.A, Thieffine, S, Vulpetti, A, Cristiani, C, Valsasina, B, Knapp, S, Kalisz, H.M, Flocco, M. | | 登録日 | 2003-07-29 | | 公開日 | 2003-10-21 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Characterization of the Gsk-3Beta Active Site Using Selective and Non-selective ATP-Mimetic Inhibitors
J.Mol.Biol., 333, 2003
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1PXL
 | | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR [4-(2,4-Dimethyl-thiazol-5-yl)-pyrimidin-2-yl]-(4-trifluoromethyl-phenyl)-amine | | 分子名称: | 4-(2,4-DIMETHYL-1,3-THIAZOL-5-YL)-N-[4-(TRIFLUOROMETHYL)PHENYL]PYRIMIDIN-2-AMINE, Cell division protein kinase 2 | | 著者 | Wu, S.Y, McNae, I, Kontopidis, G, McClue, S.J, McInnes, C, Stewart, K.J, Wang, S, Zheleva, D.I, Marriage, H, Lane, D.P, Taylor, P, Fischer, P.M, Walkinshaw, M.D. | | 登録日 | 2003-07-04 | | 公開日 | 2003-12-09 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop
Structure, 11, 2003
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2N7K
 | | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8 | | 分子名称: | NEDD8, Protein KHNYN | | 著者 | Santonico, E, Nepravishta, R, Mattioni, A, Valentini, E, Mandaliti, W, Procopio, R, Iannuccelli, M, Castagnoli, L, Polo, S, Paci, M, Cesareni, G. | | 登録日 | 2015-09-14 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Unveiling the structural determinants of KIAA0323 binding preference for NEDD8
To be Published
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2NNT
 | | General structural motifs of amyloid protofilaments | | 分子名称: | Transcription elongation regulator 1 | | 著者 | Ferguson, N, Becker, J, Tidow, H, Tremmel, S, Sharpe, T.D, Krause, G, Flinders, J, Petrovich, M, Berriman, J, Oschkinat, H, Fersht, A.R. | | 登録日 | 2006-10-24 | | 公開日 | 2006-11-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLID-STATE NMR | | 主引用文献 | General structural motifs of amyloid protofilaments.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2K3X
 | | Solution structure of EAF3 chromo barrel domain | | 分子名称: | Chromatin modification-related protein EAF3 | | 著者 | Mer, G, Xu, C. | | 登録日 | 2008-05-19 | | 公開日 | 2008-09-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S.
Structure, 16, 2008
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1SAN
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