4ODV
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4YPL
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4OC5
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![BU of 4oc5 by Molmil](/molmil-images/mine/4oc5) | X-ray structure of of human glutamate carboxypeptidase II (GCPII) in a complex with CHIBzL, a urea-based inhibitor N~2~-{[(S)-carboxy(4-hydroxyphenyl)methyl]carbamoyl}-N~6~-(4-iodobenzoyl)-L-lysine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Pavlicek, J, Ptacek, J, Cerny, J, Byun, Y, Skultetyova, L, Pomper, M, Lubkowski, J, Barinka, C. | 登録日 | 2014-01-08 | 公開日 | 2014-05-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural characterization of P1'-diversified urea-based inhibitors of glutamate carboxypeptidase II. Bioorg.Med.Chem.Lett., 24, 2014
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4OEA
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![BU of 4oea by Molmil](/molmil-images/mine/4oea) | Crystal structure of AR-LBD | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor | 著者 | Liu, J.S, Hsu, C.L, Wu, W.G. | 登録日 | 2014-01-12 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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4OCN
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4ONA
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4YW8
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![BU of 4yw8 by Molmil](/molmil-images/mine/4yw8) | Structure of rat cytosolic pepck in complex with 3-mercaptopicolinic acid | 分子名称: | 1,2-ETHANEDIOL, 3-sulfanylpyridine-2-carboxylic acid, MANGANESE (II) ION, ... | 著者 | Balan, M.D, Johnson, T.A, Mcleod, M.J, Lotosky, W.R, Holyoak, T. | 登録日 | 2015-03-20 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Inhibition and Allosteric Regulation of Monomeric Phosphoenolpyruvate Carboxykinase by 3-Mercaptopicolinic Acid. Biochemistry, 54, 2015
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4OF4
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![BU of 4of4 by Molmil](/molmil-images/mine/4of4) | X-ray structure of unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 A resolution | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SODIUM ION, ... | 著者 | Balaev, V.V, Lashkov, A.A, Gabdulkhakov, A.G, Betzel, C, Mikhailov, A.M. | 登録日 | 2014-01-14 | 公開日 | 2015-02-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | X-ray structure of unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 1.4 A resolution To be Published
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4YSA
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![BU of 4ysa by Molmil](/molmil-images/mine/4ysa) | Completely oxidized structure of copper nitrite reductase from Geobacillus thermodenitrificans | 分子名称: | COPPER (II) ION, Nitrite reductase, SODIUM ION | 著者 | Fukuda, Y, Tse, K.M, Suzuki, M, Diederichs, K, Hirata, K, Nakane, T, Sugahara, M, Nango, E, Tono, K, Joti, Y, Kameshima, T, Song, C, Hatsui, T, Yabashi, M, Nureki, O, Matsumura, H, Inoue, T, Iwata, S, Mizohata, E. | 登録日 | 2015-03-17 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Redox-coupled structural changes in nitrite reductase revealed by serial femtosecond and microfocus crystallography J.Biochem., 159, 2016
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4YWK
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4ONZ
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4OFR
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![BU of 4ofr by Molmil](/molmil-images/mine/4ofr) | Crystal structure of AR-LBD bound with co-regulator peptide | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide | 著者 | Liu, J.S, Hsu, C.L, Wu, W.G. | 登録日 | 2014-01-15 | 公開日 | 2014-08-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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4YSW
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![BU of 4ysw by Molmil](/molmil-images/mine/4ysw) | Structure of rat xanthine oxidoreductase, C-terminal deletion protein variant, NADH bound form | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BICARBONATE ION, CALCIUM ION, ... | 著者 | Nishino, T, Okamoto, K, Kawaguchi, Y, Matsumura, T, Eger, B.T, Pai, E.F. | 登録日 | 2015-03-17 | 公開日 | 2015-04-22 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase. Febs J., 282, 2015
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4OFU
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![BU of 4ofu by Molmil](/molmil-images/mine/4ofu) | Crystal structure of AR-LBD bound with co-regulator peptide | 分子名称: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, co-regulator peptide | 著者 | Liu, J.S, Hsu, C.L, Wu, W.G. | 登録日 | 2014-01-15 | 公開日 | 2014-08-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
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4YTZ
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![BU of 4ytz by Molmil](/molmil-images/mine/4ytz) | Rat xanthine oxidoreductase, C-terminal deletion protein variant, crystal grown without dithiothreitol | 分子名称: | BICARBONATE ION, CALCIUM ION, FE2/S2 (INORGANIC) CLUSTER, ... | 著者 | Nishino, T, Okamoto, K, Kawaguchi, Y, Matsumura, T, Eger, B.T, Pai, E.F, Nishino, T. | 登録日 | 2015-03-18 | 公開日 | 2015-04-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase Febs J., 282, 2015
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4YUY
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4OP1
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![BU of 4op1 by Molmil](/molmil-images/mine/4op1) | GKRP bound to AMG0556 and Sorbitol-6-Phosphate | 分子名称: | (2S)-2-(6-{5-[(6-aminopyridin-3-yl)sulfonyl]thiophen-2-yl}-5-chloropyridin-3-yl)-1,1,1-trifluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | 著者 | Jordan, S.R, Chmait, S. | 登録日 | 2014-02-04 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis. J.Med.Chem., 58, 2015
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4YVX
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![BU of 4yvx by Molmil](/molmil-images/mine/4yvx) | Crystal structure of AKR1C3 complexed with glimepiride | 分子名称: | 3-ethyl-4-methyl-N-[2-(4-{[(cis-4-methylcyclohexyl)carbamoyl]sulfamoyl}phenyl)ethyl]-2-oxo-2,5-dihydro-1H-pyrrole-1-car boxamide, Aldo-keto reductase family 1 member C3, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhao, Y, Zheng, X, Zhang, H, Hu, X. | 登録日 | 2015-03-20 | 公開日 | 2015-11-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | In vitro inhibition of AKR1Cs by sulphonylureas and the structural basis Chem.Biol.Interact., 240, 2015
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4OQE
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![BU of 4oqe by Molmil](/molmil-images/mine/4oqe) | Crystal structure of the tylM1 N,N-dimethyltransferase in complex with SAH and TDP-Fuc3NMe | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, dTDP-3-N-methylamino-3,6-dideoxygalactose, dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 著者 | Thoden, J.B, Holden, H.M. | 登録日 | 2014-02-08 | 公開日 | 2014-02-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Production of a novel N-monomethylated dideoxysugar. Biochemistry, 53, 2014
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4OQP
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4YA0
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4YBI
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![BU of 4ybi by Molmil](/molmil-images/mine/4ybi) | Crystal structure of BACE with amino thiazine inhibitor LY2811376 | 分子名称: | (4S)-4-[2,4-difluoro-5-(pyrimidin-5-yl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Beta-secretase 1, GLYCEROL | 著者 | Timm, D.E. | 登録日 | 2015-02-18 | 公開日 | 2015-04-01 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Robust central reduction of amyloid-beta in humans with an orally available, non-peptidic beta-secretase inhibitor. J.Neurosci., 31, 2011
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4OR0
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![BU of 4or0 by Molmil](/molmil-images/mine/4or0) | Crystal Structure of Bovine Serum Albumin in complex with naproxen | 分子名称: | (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, DI(HYDROXYETHYL)ETHER, Serum albumin, ... | 著者 | Zielinski, K, Bujacz, A, Sekula, B, Bujacz, G. | 登録日 | 2014-02-10 | 公開日 | 2014-06-04 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen. Proteins, 82, 2014
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4YCO
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![BU of 4yco by Molmil](/molmil-images/mine/4yco) | E. coli dihydrouridine synthase C (DusC) in complex with tRNAPhe | 分子名称: | FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, MANGANESE (II) ION, ... | 著者 | Byrne, R.T, Jenkins, H.T, Peters, D.T, Whelan, F, Stowell, J, Aziz, N, Kasatsky, P, Rodnina, M.V, Koonin, E.V, Konevega, A.L, Antson, A.A. | 登録日 | 2015-02-20 | 公開日 | 2015-04-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Major reorientation of tRNA substrates defines specificity of dihydrouridine synthases. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OSP
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![BU of 4osp by Molmil](/molmil-images/mine/4osp) | The crystal structure of urdamycin C-6 ketoreductase domain UrdMred with bound NADP and rabelomycin | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxygenase-reductase, rabelomycin | 著者 | Niiranen, L, Paananen, P, Patrikainen, P, Metsa-Ketela, M. | 登録日 | 2014-02-13 | 公開日 | 2014-10-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure-based engineering of angucyclinone 6-ketoreductases. Chem.Biol., 21, 2014
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