PDB: 1731 件ウェブページステータス検索Chemie searchBIRD

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7CL7	Substrate-free structure of CYP154C2 from Streptomyces avermitilis in an open conformation 分子名称: Cytochrome P450 hydroxylase, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE 著者 Xu, L.H, Fushinobu, S. 登録日 2020-07-20 公開日 2021-07-21 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Substrate-free structure of CYP154C2 in an open conformation To Be Published
7PQ1	Ligand-free crystal structure of a staphylococcal orthologue of CYP134A1 分子名称: Cytochrome P450 protein, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Snee, M, Levy, C, Leys, D, Katariya, M, Munro, A.W. 登録日 2021-09-15 公開日 2022-09-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with Cyclo-L-leucyl-L-leucine To Be Published
5CWE	Structure of CYP107L2 from Streptomyces avermitilis with lauric acid 分子名称: Cytochrome P450 hydroxylase, GLYCEROL, LAURIC ACID, ... 著者 Pham, T.-V, Han, S.-H, Kim, J.-H, Kim, D.-H, Kang, L.-W. 登録日 2015-07-28 公開日 2016-08-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structure of CYP107L2 from Streptomyces avermitilis with lauric acid To Be Published
6DAA	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[(pyridin-3-yl)methyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAJ	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLUTAMINE, GLYCEROL, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAB	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAL	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLYCEROL, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[2-(pyridin-3-yl)ethyl]-D-phenylalaninamide, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAC	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-{[(2R)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DA3	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2R)-1-oxo-3-phenyl-1-{[(pyridin-3-yl)methyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DA2	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DA5	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2S)-1-oxo-3-phenyl-1-{[(pyridin-3-yl)methyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DAG	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2R)-1-{[(2S)-1-oxo-3-phenyl-1-{[2-(pyridin-3-yl)ethyl]amino}propan-2-yl]sulfanyl}-3-phenylpropan-2-yl]carbamate 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6DA8	Human CYP3A4 bound to an inhibitor 分子名称: Cytochrome P450 3A4, Nalpha-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl}-N-[(pyridin-3-yl)methyl]-D-phenylalaninamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F. 登録日 2018-05-01 公開日 2019-04-03 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.802 Å) 主引用文献 Structure-Activity Relationships of Rationally Designed Ritonavir Analogues: Impact of Side-Group Stereochemistry, Headgroup Spacing, and Backbone Composition on the Interaction with CYP3A4. Biochemistry, 58, 2019
6Q2C	Domain-swapped dimer of Acanthamoeba castellanii CYP51 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Obtusifoliol 14alphademethylase, ... 著者 Sharma, V, Podust, L.M. 登録日 2019-08-07 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole. Mol.Pharmacol., 98, 2020
8B2P	CYP153A71 from Acinetobacter dieselolei bound to octanoic acid 分子名称: Cytochrome P450 alkane hydroxylase, OCTANOIC ACID (CAPRYLIC ACID), PROTOPORPHYRIN IX CONTAINING FE 著者 Opperman, D.J, Tolmie, C. 登録日 2022-09-14 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 CYP153A71 from Alcanivorax dieselolei: Oxidation beyond Monoterminal Hydroxylation of n-Alkanes Catalysts, 2022
6UW2	Clotrimazole bound complex of Acanthamoeba castellanii CYP51 分子名称: 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, GUANIDINE, Obtusifoliol 14alphademethylase, ... 著者 Sharma, V, Podust, L.M. 登録日 2019-11-04 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole. Mol.Pharmacol., 98, 2020
6UX0	Isavuconazole bound complex of Acanthamoeba castellanii CYP51 分子名称: 4-{2-[(2R,3R)-3-(2,5-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl}benzonitrile, FE (III) ION, Obtusifoliol 14alphademethylase, ... 著者 Sharma, V, Podust, L.M. 登録日 2019-11-06 公開日 2020-10-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Domain-Swap Dimerization of Acanthamoeba castellanii CYP51 and a Unique Mechanism of Inactivation by Isavuconazole. Mol.Pharmacol., 98, 2020
1ROM	CRYSTAL STRUCTURE OF NITRIC REDUCTASE FROM DENITRIFYING FUNGUS FUSARIUM OXYSPORUM 分子名称: CYTOCHROME P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Nakagawa, A. 登録日 1997-03-24 公開日 1997-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum. Nat.Struct.Biol., 4, 1997
4E2P	Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis 分子名称: Cytochrome P450 107B1 (P450CVIIB1), MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Zhang, H.D, Chen, J, Wang, H, Huang, L, Zhang, H.J. 登録日 2012-03-09 公開日 2013-03-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 Crystal Structure of a Post-tailoring Hydroxylase (HmtN) Involved in the Himastatin Biosynthesis To be Published
8ADR	Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a fragment 分子名称: Cytochrome P450 protein, PROTOPORPHYRIN IX CONTAINING FE, pyridin-3-ylboronic acid 著者 Snee, M, Katariya, M, Levy, C. 登録日 2022-07-11 公開日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Crystal structure of a staphylococcal orthologue of CYP134A1 (CYPX) in complex with a fragment To Be Published
3DAX	Crystal structure of human CYP7A1 分子名称: Cytochrome P450 7A1, PROTOPORPHYRIN IX CONTAINING FE, UNKNOWN ATOM OR ION 著者 Strushkevich, N.V, Tempel, W, Dombrovski, L, Dong, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2008-05-30 公開日 2008-08-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of human CYP7A1 To be Published
1CL6	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND ITS SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-06 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
1CMN	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND THEIR SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-07 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
1CMJ	CRYSTAL STRUCTURES OF FERRIC-NO COMPLEXES OF FUNGAL NITRIC OXIDE REDUCTASE AND THEIR SER286 MUTANTS AT CRYOGENIC TEMPERATURE 分子名称: CYTOCHROME P450, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Park, S.-Y, Shiro, Y. 登録日 1999-05-07 公開日 2000-03-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Proton delivery in NO reduction by fungal nitric-oxide reductase. Cryogenic crystallography, spectroscopy, and kinetics of ferric-NO complexes of wild-type and mutant enzymes. J.Biol.Chem., 275, 2000
8HGD	Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei 分子名称: Cytochrome P450, GLYCEROL, METHANOL, ... 著者 Jiang, Y, Cong, Z. 登録日 2022-11-14 公開日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Crystal structure of the CYP153A mutant V456A from Marinobacter aquaeolei To Be Published

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