PDB: 1555 件ウェブページステータス検索Chemie searchBIRD

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3PJJ	Synthetic Dimer of Human Carbonic Anhydrase II 分子名称: 1,1'-(oxydimethanediyl)dipyrrolidine-2,5-dione, Carbonic anhydrase 2, ZINC ION 著者 Snyder, P.W, Kwant, R.L, Moustakas, D.T, Mack, E.T, Butte, M.J, Whitesides, G.W. 登録日 2010-11-10 公開日 2012-01-18 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 One Interface Stabilizes Linear Chains in All Polymorphs of Crystals of Human Carbonic Anhydrase II To be Published
6Y74	X-ray crystal structure of human carbonic anhydrase IX catalytic domain. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, CHLORIDE ION, ... 著者 Fisher, S.Z, Koruza, K. 登録日 2020-02-28 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX Int J Mol Sci, 21, 2020
6YRI	THE CRYSTAL STRUCTURE OF THE COMPLEX OF HCAII WITH CAFFEIC ACID 分子名称: CAFFEIC ACID, Carbonic anhydrase 2, GLYCEROL, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2020-04-20 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Catechols: a new class of carbonic anhydrase inhibitors. Chem.Commun.(Camb.), 56, 2020
5EOI	Crystal structure of copper bound human Carbonic anhydrase II 分子名称: CHLORIDE ION, COPPER (II) ION, Carbonic anhydrase 2, ... 著者 Ferraroni, M, Scozzafava, A, Supuran, C.T. 登録日 2015-11-10 公開日 2016-11-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of copper bound human Carbonic anhydrase II to be published
6H38	The crystal structure of human carbonic anhydrase VII in complex with 4-[(4-fluorophenyl)methyl]-1-piperazinyl]benzenesulfonamide. 分子名称: 4-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 7, GLYCEROL, ... 著者 Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. 登録日 2018-07-17 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018
6H36	The crystal structure of human carbonic anhydrase VII in complex with 4-(4-phenylpiperidine-1-carbonyl)benzenesulfonamide. 分子名称: 4-(4-phenylpiperidin-1-yl)carbonylbenzenesulfonamide, Carbonic anhydrase 7, ZINC ION 著者 Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. 登録日 2018-07-17 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018
6H37	The crystal structure of human carbonic anhydrase VII in complex with 4-(4-phenyl)-4-hydroxy-1-piperidine-1-carbonyl)benzenesulfonamide 分子名称: 4-(4-oxidanyl-4-phenyl-piperidin-1-yl)carbonylbenzenesulfonamide, Carbonic anhydrase 7, ZINC ION 著者 Buemi, M.R, Di Fiore, A, De Luca, L, Ferro, S, Mancuso, F, Monti, S.M, Buonanno, M, Angeli, A, Russo, E, De Sarro, G, Supuran, C.T, De Simone, G, Gitto, R. 登録日 2018-07-17 公開日 2018-12-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. Eur J Med Chem, 163, 2018
3NJ9	Crystal structure of carbonic anhydrase II in complex with a Nir inhibitor 分子名称: 3-(4-sulfamoylphenyl)-N-[6-({(6Z)-2-[(2Z)-2-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)ethyl]-6-[(2E)-2-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)ethylidene]cyclohex-1-en-1-yl}amino)hexyl]propanamide, Carbonic anhydrase 2, MERCURY (II) ION, ... 著者 Temperini, C, Cecchi, A. 登録日 2010-06-17 公開日 2011-06-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of carbonic anhydrase II in complex with a Nir inhibitor To be Published
4QY3	THE CRYSTAL STRUCTURE OF THE COMPLEX of HCAII WITH AN ORTHO-SUBSTITUTED BENZOIC ACID 分子名称: 2-[(S)-benzylsulfinyl]benzoic acid, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase 2, ... 著者 D'Ambrosio, K, De Simone, G. 登録日 2014-07-23 公開日 2014-12-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Out of the active site binding pocket for carbonic anhydrase inhibitors. Chem.Commun.(Camb.), 51, 2014
1LG5	Crystal Structure Analysis of the HCA II Mutant T199P in complex with beta-mercaptoethanol 分子名称: BETA-MERCAPTOETHANOL, Carbonic anhydrase II, ZINC ION 著者 Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. 登録日 2002-04-15 公開日 2002-07-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant. Biochemistry, 41, 2002
1LGD	Crystal Structure Analysis of HCA II Mutant T199P in Complex with Bicarbonate 分子名称: BICARBONATE ION, Carbonic anhydrase II, ZINC ION 著者 Huang, S, Sjoblom, B, Sauer-Eriksson, A.E, Jonsson, B.-H. 登録日 2002-04-15 公開日 2002-07-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Organization of an efficient carbonic anhydrase: implications for the mechanism based on structure-function studies of a T199P/C206S mutant. Biochemistry, 41, 2002
6IVE	Molecular structure of a thermostable and a Zinc ion binding gamma-class carbonic anhydrase 分子名称: Ferripyochelin-binding protein, PHOSPHATE ION, ZINC ION 著者 Wang, W.M, Wang, H.F. 登録日 2018-12-03 公開日 2019-04-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular structure of thermostable and zinc-ion-binding gamma-class carbonic anhydrases. Biometals, 32, 2019
4PXX	Crystal structure of a highly thermal stabilized variant of Human Carbonic Anhydrase II 分子名称: CHOLIC ACID, Carbonic anhydrase 2, MAGNESIUM ION, ... 著者 Boone, C.D, Habibzadegan, A, McKenna, R. 登録日 2014-03-25 公開日 2015-06-10 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Crystal structure of a highly thermal stabilized variant of Human Carbonic Anhydrase II TO BE PUBLISHED
4RH2	Crystal structure of human carbonic anhydrase II in complex with 2-(6-hydroxy-3-Oxo-3H-xanthen-9-yl)-5-{3-1-(4-sulfamoyl-phenyl)-1h-[1,2,3]triazol-4-ylmethyl-thioureido}-benzoic acid 分子名称: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[({[1-(4-sulfamoylphenyl)-1H-1,2,3-triazol-4-yl]methyl}carbamothioyl)amino]benzoic acid, Carbonic anhydrase 2, GLYCEROL, ... 著者 Ferraroni, M. 登録日 2014-10-01 公開日 2015-11-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 New classes of carbonic anhydrase inhibitors to be published
3Q31	Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Carbonic anhydrase, D-MALATE, ... 著者 Cuesta-Seijo, J.A, Borchert, M.S, Navarro-Poulsen, J.C, Schnorr, K.M, Leggio, L.L. 登録日 2010-12-21 公開日 2011-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.703 Å) 主引用文献 Structure of fungal alpha Carbonic Anhydrase from Aspergillus oryzae To be Published
6ROF	Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide 分子名称: 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BICINE, Carbonic anhydrase 2, ... 著者 Smirnov, A, Paketuryte, V, Manakova, E, Grazulis, S. 登録日 2019-05-12 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide To Be Published
6RMX	Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide 分子名称: 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide, BENZOIC ACID, Carbonic anhydrase 2, ... 著者 Smirnov, A, Paketuryte, V, Manakova, E, Grazulis, S. 登録日 2019-05-07 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide To Be Published
6RMY	Human Carbonic anhydrase II mutant T199V bound by 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, BICINE, ... 著者 Smirnov, A, Paketuryte, V, Manakova, E, Grazulis, S. 登録日 2019-05-07 公開日 2020-06-03 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Human Carbonic anhydrase II mutant T199V bound by 3-(cyclooctylamino)-2,5,6-trifluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide To Be Published
6SYB	Crystal structure of carbonic anhydrase 2 with (3aR,4S,9bS)-4-(2-chloro-4-hydroxyphenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide 分子名称: (3~{a}~{R},4~{S},9~{b}~{S})-4-(2-chloranyl-4-oxidanyl-phenyl)-2,3,3~{a},4,5,9~{b}-hexahydro-1~{H}-cyclopenta[c]quinoline-8-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Angeli, A, Ferraroni, M. 登録日 2019-09-27 公開日 2020-10-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of carbonic anhydrase 2 with (3aR,4S,9bS)-4-(2-chloro-4-hydroxyphenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide To Be Published
6SX9	Crystal structure of carbonic anhydrase 2 with 4-(2-chlorophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide 分子名称: 4-(2-chlorophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide, Carbonic anhydrase 2, GLYCEROL, ... 著者 Angeli, A, Ferraroni, M. 登録日 2019-09-25 公開日 2020-10-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Crystal structure of carbonic anhydrase 2 with 4-(2-chlorophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide To Be Published
3V2M	Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Aggarwal, M, McKenna, A. 登録日 2011-12-12 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.471 Å) 主引用文献 Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II To be Published
3V2J	Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, A. 登録日 2011-12-12 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II To be Published
6RQU	X-ray crystal structure of H/D exchanged (H/D) small monoclinic unit cell CA IX SV. 分子名称: ACETATE ION, Carbonic anhydrase 9, ZINC ION 著者 Fisher, Z, Koruza, K. 登録日 2019-05-16 公開日 2019-10-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.393 Å) 主引用文献 Structural comparison of protiated, H/D-exchanged and deuterated human carbonic anhydrase IX. Acta Crystallogr D Struct Biol, 75, 2019
6SDH	Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 5 mM 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Gloeckner, S, Haake, M, Heine, A, Klebe, G. 登録日 2019-07-27 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.04 Å) 主引用文献 Human Carbonic Anhydrase II in complex with an inhibitor soaked at a concentration of 5 mM To Be Published
6SBM	Human Carbonic Anhydrase II in complex with 4-(pentyloxy)benzenesulfonamide 分子名称: (4-CARBOXYPHENYL)(CHLORO)MERCURY, 4-pentoxybenzenesulfonamide, CITRATE ANION, ... 著者 Gloeckner, S, Ngo, K, Heine, A, Klebe, G. 登録日 2019-07-21 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Human Carbonic Anhydrase II in complex with 4-(pentyloxy)benzenesulfonamide To Be Published

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