6ROF

Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide

Summary for 6ROF

• Entry DOI: 10.2210/pdb6rof/pdb
• Related: 6RMX 6RMY
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
• Functional Keywords: drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 30029.28

Authors

Smirnov, A.,Paketuryte, V.,Manakova, E.,Grazulis, S. (deposition date: 2019-05-12, release date: 2020-06-03, Last modification date: 2024-01-24)

• Primary citation: Smirnov, A.,Manakova, E.,Paketuryte, V.; Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)