6ROF
Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide
Summary for 6ROF
Entry DOI | 10.2210/pdb6rof/pdb |
Related | 6RMX 6RMY |
Descriptor | Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | drug design, carbonic anhydrase, benzenesulfonamide, metal-binding, lyase-lyase inhibitor complex, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30029.28 |
Authors | Smirnov, A.,Paketuryte, V.,Manakova, E.,Grazulis, S. (deposition date: 2019-05-12, release date: 2020-06-03, Last modification date: 2024-01-24) |
Primary citation | Smirnov, A.,Manakova, E.,Paketuryte, V. Human Carbonic anhydrase II mutant T199V bound by 2-(cyclooctylamino)-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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