4RH2

Crystal structure of human carbonic anhydrase II in complex with 2-(6-hydroxy-3-Oxo-3H-xanthen-9-yl)-5-{3-1-(4-sulfamoyl-phenyl)-1h-[1,2,3]triazol-4-ylmethyl-thioureido}-benzoic acid

Summary for 4RH2

• Entry DOI: 10.2210/pdb4rh2/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[({[1-(4-sulfamoylphenyl)-1H-1,2,3-triazol-4-yl]methyl}carbamothioyl)amino]benzoic acid, ... (5 entities in total)
• Functional Keywords: lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm : P00918
• Total number of polymer chains: 1
• Total formula weight: 30089.23

Authors

Ferraroni, M. (deposition date: 2014-10-01, release date: 2015-11-11, Last modification date: 2023-09-20)

• Primary citation: Ferraroni, M.,Supuran, C.T.,Carta, F.,Bozdag, M.,Scozzafava, A.; New classes of carbonic anhydrase inhibitors; to be published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)