5IB1
 
 | | Crystal structure of HLA-B*27:05 complexed with the self-peptide pVIPR measured at 295 K | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ... | | 著者 | Janke, R, Ballaschk, M, Schmieder, P, Uchanska-Ziegler, B, Ziegler, A, Loll, B. | | 登録日 | 2016-02-22 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Metal-triggered conformational reorientation of a self-peptide bound to a disease-associated HLA-B*27 subtype.
J.Biol.Chem., 2019
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1KWM
 | | Human procarboxypeptidase B: Three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI) | | 分子名称: | CITRIC ACID, Procarboxypeptidase B, ZINC ION | | 著者 | Pereira, P.J.B, Segura-Martin, S, Ferrer-Orta, C, Vendrell, J, Aviles, F.-X, Coll, M, Gomis-Rueth, F.-X. | | 登録日 | 2002-01-30 | | 公開日 | 2002-06-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Human procarboxypeptidase B: three-dimensional structure and implications for thrombin-activatable fibrinolysis inhibitor (TAFI).
J.Mol.Biol., 321, 2002
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6EBX
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3ETA
 | | Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor | | 分子名称: | 1-(3-{5-[4-(aminomethyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl}phenyl)-3-(2-phenoxyphenyl)urea, insulin receptor, kinase domain | | 著者 | Patnaik, S, Stevens, K, Gerding, R, Deanda, F, Shotwell, B, Tang, J, Hamajima, T, Nakamura, H, Leesnitzer, A, Hassell, A, Shewchuk, L, Kumar, R, Lei, H, Chamberlain, S. | | 登録日 | 2008-10-07 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Discovery of 3,5-disubstituted-1H-pyrrolo[2,3-b]pyridines as potent inhibitors of the insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase.
Bioorg.Med.Chem.Lett., 19, 2009
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5FPW
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4BOM
 | | Structure of herpesvirus fusion glycoprotein B-bilayer complex revealing the protein-membrane and lateral protein-protein interaction | | 分子名称: | ENVELOPE GLYCOPROTEIN B | | 著者 | Maurer, U.E, Zeev-Ben-Mordehai, Z, Pandurangan, A.P, Cairns, T.M, Hannah, B.P, Whitbeck, J.C, Eisenberg, R.J, Cohen, G.H, Topf, M, Huiskonen, J.T, Grunewald, K. | | 登録日 | 2013-05-21 | | 公開日 | 2013-07-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (27 Å) | | 主引用文献 | The structure of herpesvirus fusion glycoprotein B-bilayer complex reveals the protein-membrane and lateral protein-protein interaction.
Structure, 21, 2013
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1IMJ
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4PP7
 | | Highly Potent and Selective 3-N-methylquinazoline-4(3H)-one Based Inhibitors of B-RafV600E Kinase | | 分子名称: | N-{2,4-difluoro-3-[methyl(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf | | 著者 | Wenglowsky, S, Ren, L, Grina, J, Hansen, J.D, Laird, E.R, Moreno, D, Dinkel, V, Gloor, S.L, Hastings, G, Rana, S, Rasor, K, Sturgis, H.L, Voegtli, W.C, Vigers, G.P.A, Willis, B, Mathieu, S, Rudolph, J. | | 登録日 | 2014-02-26 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
Bioorg.Med.Chem.Lett., 24, 2014
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4RGO
 | | Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 14G8 | | 分子名称: | 14G8 heavy chain, 14G8 light chain, ACETATE ION, ... | | 著者 | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | | 登録日 | 2014-09-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
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4RGM
 | | Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 20B1 | | 分子名称: | 20B1 heavy chain, 20B1 light chain, Enterotoxin type B | | 著者 | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | | 登録日 | 2014-09-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.689 Å) | | 主引用文献 | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
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4RGN
 | | Structure of Staphylococcal Enterotoxin B bound to two neutralizing antibodies, 14G8 and 6D3 | | 分子名称: | 14G8 heavy chain, 14G8 light chain, 6D3 heavy chain, ... | | 著者 | Franklin, M.C, Dutta, K, Varshney, A.K, Goger, M.J, Fries, B.C. | | 登録日 | 2014-09-30 | | 公開日 | 2015-01-21 | | 最終更新日 | 2024-11-27 | | 実験手法 | X-RAY DIFFRACTION (2.698 Å) | | 主引用文献 | Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies.
J.Biol.Chem., 290, 2015
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7EOY
 | | Engineered Hepatitis B virus core antigen T=3 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-04-24 | | 公開日 | 2021-09-01 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7FDJ
 | | Engineered Hepatitis B virus core antigen with short linker T=4 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-07-16 | | 公開日 | 2021-09-01 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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7EP6
 | | Engineered Hepatitis B virus core antigen T=4 | | 分子名称: | Capsid protein,Immunoglobulin G-binding protein A | | 著者 | Jeong, H, Heo, Y, Yoo, Y, Ryu, B, Yun, J, Cho, H, Lee, W. | | 登録日 | 2021-04-26 | | 公開日 | 2021-09-01 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | Structural and Functional Characterizations of Cancer Targeting Nanoparticles Based on Hepatitis B Virus Capsid.
Int J Mol Sci, 22, 2021
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4AP7
 | | Crystal structure of C-MET kinase domain in complex with 4-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl)phenol | | 分子名称: | 4-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methyl]phenol, HEPATOCYTE GROWTH FACTOR RECEPTOR | | 著者 | McTigue, M, Wickersham, J. | | 登録日 | 2012-03-30 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Discovery of a Novel Class of Exquisitely Selective Mesenchymal-Epithelial Transition Factor (C-met) Protein Kinase Inhibitors and Identification of the Clinical Candidate 2-(4-(1-(Quinolin-6-Ylmethyl)-1H-[1,2, 3]Triazolo[4,5-B]Pyrazin-6-Yl)-1H-Pyrazol-1-Yl)Ethanol (Pf-04217903) for the Treatment of Cancer.
J.Med.Chem., 55, 2012
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3VBC
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4O3X
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3MXG
 | | Structure of Shiga Toxin type 2 (Stx2) B Pentamer Mutant Q40L | | 分子名称: | D-xylose, Shiga-like toxin 2 subunit B | | 著者 | Kovall, R.A, Vander Wielen, B.D, Friedmann, D.R, Flagler, M.J. | | 登録日 | 2010-05-07 | | 公開日 | 2011-01-12 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Molecular basis of differential B-pentamer stability of Shiga toxins 1 and 2.
Plos One, 5, 2010
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1NFK
 | | STRUCTURE OF THE NUCLEAR FACTOR KAPPA-B (NF-KB) P50 HOMODIMER | | 分子名称: | DNA (5'-D(*TP*GP*GP*GP*AP*AP*TP*TP*CP*CP*C)-3'), PROTEIN (NUCLEAR FACTOR KAPPA-B (NF-KB)) | | 著者 | Ghosh, G, Van Duyne, G, Ghosh, S, Sigler, P.B. | | 登録日 | 1995-02-28 | | 公開日 | 1996-12-23 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of NF-kappa B p50 homodimer bound to a kappa B site.
Nature, 373, 1995
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3D4Q
 | | Pyrazole-based inhibitors of B-Raf kinase | | 分子名称: | (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime, B-Raf proto-oncogene serine/threonine-protein kinase | | 著者 | Morales, T, Vigers, G.P.A, Brandhuber, B.J. | | 登録日 | 2008-05-14 | | 公開日 | 2008-08-19 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Potent and selective pyrazole-based inhibitors of B-Raf kinase.
Bioorg.Med.Chem.Lett., 18, 2008
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1T0Y
 | | Solution Structure of a Ubiquitin-Like Domain from Tubulin-binding Cofactor B | | 分子名称: | tubulin folding cofactor B | | 著者 | Lytle, B.L, Peterson, F.C, Qui, S.H, Luo, M, Volkman, B.F, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2004-04-13 | | 公開日 | 2004-04-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of a Ubiquitin-like Domain from Tubulin-binding Cofactor B.
J.Biol.Chem., 279, 2004
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5A6V
 | | Open and closed conformations and protonation states of Candida antarctica Lipase B: Xenon complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, LIPASE B, ... | | 著者 | Stauch, B, Fisher, S.J, Cianci, M. | | 登録日 | 2015-07-01 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Open and Closed States of Candida Antarctica Lipase B: Protonation and the Mechanism of Interfacial Activation.
J.Lipid Res., 56, 2015
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1XH3
 | | Conformational Restraints and Flexibility of 14-Meric Peptides in Complex with HLA-B*3501 | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ... | | 著者 | Probst-Kepper, M, Hecht, H.J, Herrmann, H, Janke, V, Ocklenburg, F, Klempnauer, J, van den Eynde, B.J, Weiss, S. | | 登録日 | 2004-09-17 | | 公開日 | 2004-11-23 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Conformational restraints and flexibility of 14-meric peptides in complex with HLA-B*3501.
J.Immunol., 173, 2004
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5A71
 | | Open and closed conformations and protonation states of Candida antarctica Lipase B: atomic resolution native | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ISOPROPYL ALCOHOL, LIPASE B, ... | | 著者 | Stauch, B, Fisher, S.J, Cianci, M. | | 登録日 | 2015-07-02 | | 公開日 | 2015-10-21 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (0.91 Å) | | 主引用文献 | Open and Closed States of Candida Antarctica Lipase B: Protonation and the Mechanism of Interfacial Activation.
J.Lipid Res., 56, 2015
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1TGO
 | | THERMOSTABLE B TYPE DNA POLYMERASE FROM THERMOCOCCUS GORGONARIUS | | 分子名称: | PROTEIN (THERMOSTABLE B DNA POLYMERASE) | | 著者 | Hopfner, K.-P, Eichinger, A, Engh, R.A, Laue, F, Ankenbauer, W, Huber, R, Angerer, B. | | 登録日 | 1999-02-23 | | 公開日 | 1999-03-22 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of a thermostable type B DNA polymerase from Thermococcus gorgonarius.
Proc.Natl.Acad.Sci.USA, 96, 1999
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