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5FTJ
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Cryo-EM structure of human p97 bound to UPCDC30245 inhibitor
分子名称: 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE, ADENOSINE-5'-DIPHOSPHATE, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE
著者Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5FTN
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Cryo-EM structure of human p97 bound to ATPgS (Conformation III)
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE
著者Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S.
登録日2016-01-14
公開日2016-01-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition
Science, 351, 2016
5C1A
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BU of 5c1a by Molmil
p97-N750D/R753D/M757D/Q760D in complex with ATP-gamma-S
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C18
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p97-delta709-728 in complex with ATP-gamma-S
分子名称: CHLORIDE ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C19
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BU of 5c19 by Molmil
p97 variant 2 in the apo state
分子名称: SULFATE ION, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97.
Structure, 24, 2016
5C1B
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BU of 5c1b by Molmil
p97-delta709-728 in complex with a UFD1-SHP peptide
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Haenzelmann, P, Schindelin, H.
登録日2015-06-13
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions.
Structure, 24, 2016
4RV0
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BU of 4rv0 by Molmil
Crystal structure of TN complex
分子名称: Nuclear protein localization protein 4 homolog, SULFATE ION, Transitional endoplasmic reticulum ATPase TER94
著者Hao, Q, Jiao, S, Shi, Z.B, Zhou, Z.C.
登録日2014-11-23
公開日2015-11-25
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Crystal structure of TN complex
To be Published
4UZR
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BU of 4uzr by Molmil
Crystal Structure of Pyrococcus horikoshii Ph1500
分子名称: PUTATIVE UNCHARACTERIZED PROTEIN PH1500
著者Hartmann, M.D, Ammelburg, M, Djuranovic, S, Lupas, A.N.
登録日2014-09-08
公開日2015-10-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Crystal Structure of Pyrococcus Horikoshii Ph1500
To be Published
3J99
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BU of 3j99 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J96
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BU of 3j96 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J95
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BU of 3j95 by Molmil
Structure of ADP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy
分子名称: ADENOSINE-5'-DIPHOSPHATE, Vesicle-fusing ATPase
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J94
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BU of 3j94 by Molmil
Structure of ATP-bound N-ethylmaleimide sensitive factor determined by single particle cryoelectron microscopy
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Vesicle-fusing ATPase
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J98
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BU of 3j98 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.4 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
3J97
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BU of 3j97 by Molmil
Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II)
分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ...
著者Zhao, M, Wu, S, Cheng, Y, Brunger, A.T.
登録日2014-12-05
公開日2015-01-28
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanistic insights into the recycling machine of the SNARE complex.
Nature, 518, 2015
4KDL
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BU of 4kdl by Molmil
Crystal structure of p97/VCP N in complex with OTU1 UBXL
分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1
著者Kim, S.J, Kim, E.E.
登録日2013-04-25
公開日2014-03-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
4KDI
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BU of 4kdi by Molmil
Crystal structure of p97/VCP N in complex with OTU1 UBXL
分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1
著者Kim, S.J, Kim, E.E.
登録日2013-04-25
公開日2014-03-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP).
J.Biol.Chem., 289, 2014
2M3X
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BU of 2m3x by Molmil
Solution structure of Ph1500: a homohexameric protein centered on a 12-bladed beta-propeller
分子名称: PH1500
著者Varnay, I, Truffault, V, Kessler, H, Coles, M.
登録日2013-01-28
公開日2014-01-29
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of Ph1500: a homohexameric protein centered on a 12-bladed beta-propeller
To be Published
4KLN
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BU of 4kln by Molmil
Structure of p97 N-D1 A232E mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-07
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
4KOD
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BU of 4kod by Molmil
Structure of p97 N-D1 R155H mutant in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
4KO8
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BU of 4ko8 by Molmil
Structure of p97 N-D1 R155H mutant in complex with ATPgS
分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
著者Xia, D, Tang, W.K.
登録日2013-05-11
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem., 288, 2013
3QWZ
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BU of 3qwz by Molmil
Crystal structure of FAF1 UBX-p97N-domain complex
分子名称: FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
著者Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E.
登録日2011-02-28
公開日2012-05-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dissection of the interaction between FAF1 UBX and p97
To be Published
3TIW
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BU of 3tiw by Molmil
Crystal structure of p97N in complex with the C-terminus of gp78
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2011-08-22
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
J.Biol.Chem., 286, 2011
3QC8
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BU of 3qc8 by Molmil
Crystal Structure of FAF1 UBX Domain In Complex with p97/VCP N Domain Reveals The Conserved FcisP Touch-Turn Motif of UBX Domain Suffering Conformational Change
分子名称: FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
著者Kim, K.H, Kang, W, Suh, S.W, Yang, J.K.
登録日2011-01-15
公開日2011-07-20
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain
Proteins, 79, 2011
3QQ8
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BU of 3qq8 by Molmil
Crystal structure of p97-N in complex with FAF1-UBX
分子名称: CHLORIDE ION, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2011-02-15
公開日2011-06-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011
3QQ7
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Crystal Structure of the p97 N-terminal domain
分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ...
著者Haenzelmann, P, Schindelin, H.
登録日2011-02-15
公開日2011-06-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Hierarchical Binding of Cofactors to the AAA ATPase p97.
Structure, 19, 2011

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