7KC0
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![BU of 7kc0 by Molmil](/molmil-images/mine/7kc0) | Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... | 著者 | Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. | 登録日 | 2020-10-04 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-16 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
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3JA9
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3L0W
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![BU of 3l0w by Molmil](/molmil-images/mine/3l0w) | Structure of split monoubiquitinated PCNA with ubiquitin in position two | 分子名称: | Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | 登録日 | 2009-12-10 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
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6HVO
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![BU of 6hvo by Molmil](/molmil-images/mine/6hvo) | Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta | 分子名称: | DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION | 著者 | Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A. | 登録日 | 2018-10-11 | 公開日 | 2019-01-23 | 最終更新日 | 2019-03-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA). J.Biol.Chem., 294, 2019
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5DA7
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![BU of 5da7 by Molmil](/molmil-images/mine/5da7) | monomeric PCNA bound to a small protein inhibitor | 分子名称: | DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ... | 著者 | Ladner, J.E, Altieri, A.S, Kelman, Z. | 登録日 | 2015-08-19 | 公開日 | 2016-05-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp. Nucleic Acids Res., 44, 2016
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3L10
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![BU of 3l10 by Molmil](/molmil-images/mine/3l10) | Structure of split monoubiquitinated PCNA with ubiquitin in position one | 分子名称: | Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen | 著者 | Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T. | 登録日 | 2009-12-10 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange. Nat.Struct.Mol.Biol., 17, 2010
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6K3A
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5DAI
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7M5M
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![BU of 7m5m by Molmil](/molmil-images/mine/7m5m) | PCNA bound to peptide mimetic | 分子名称: | N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2021-03-24 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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7M5L
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7M5N
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![BU of 7m5n by Molmil](/molmil-images/mine/7m5n) | PCNA bound to peptide mimetic with linker | 分子名称: | 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2021-03-24 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
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7KQ1
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![BU of 7kq1 by Molmil](/molmil-images/mine/7kq1) | PCNA bound to truncated peptide mimetic | 分子名称: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2020-11-13 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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7KQ0
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![BU of 7kq0 by Molmil](/molmil-images/mine/7kq0) | PCNA bound to peptide mimetic | 分子名称: | LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen | 著者 | Vandborg, B.A, Bruning, J.B. | 登録日 | 2020-11-13 | 公開日 | 2021-05-19 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
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6KNB
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![BU of 6knb by Molmil](/molmil-images/mine/6knb) | PolD-PCNA-DNA (form A) | 分子名称: | DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ... | 著者 | Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y. | 登録日 | 2019-08-05 | 公開日 | 2020-08-05 | 最終更新日 | 2021-02-17 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy. Bmc Biol., 18, 2020
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5AUJ
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6KNC
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![BU of 6knc by Molmil](/molmil-images/mine/6knc) | PolD-PCNA-DNA (form B) | 分子名称: | DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ... | 著者 | Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y. | 登録日 | 2019-08-05 | 公開日 | 2020-08-05 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (9.3 Å) | 主引用文献 | Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy. Bmc Biol., 18, 2020
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5E0U
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5E0V
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2HIK
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2HII
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6S1O
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![BU of 6s1o by Molmil](/molmil-images/mine/6s1o) | Human polymerase delta holoenzyme Conformer 3 | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-06-19 | 公開日 | 2019-12-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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6AIG
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6T7Y
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![BU of 6t7y by Molmil](/molmil-images/mine/6t7y) | Structure of PCNA bound to cPIP motif of DP2 from P. abyssi | 分子名称: | DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD | 著者 | Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L. | 登録日 | 2019-10-23 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020
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6CX2
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![BU of 6cx2 by Molmil](/molmil-images/mine/6cx2) | S177G Mutant of Yeast PCNA | 分子名称: | Proliferating cell nuclear antigen | 著者 | Powers, K.T. | 登録日 | 2018-04-02 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.101 Å) | 主引用文献 | Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis. PLoS ONE, 11, 2016
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6TNY
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![BU of 6tny by Molmil](/molmil-images/mine/6tny) | Processive human polymerase delta holoenzyme | 分子名称: | DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... | 著者 | Lancey, C, Hamdan, S.M, De Biasio, A. | 登録日 | 2019-12-10 | 公開日 | 2019-12-18 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
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