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7KC0
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BU of 7kc0 by Molmil
Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ...
著者Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E.
登録日2020-10-04
公開日2020-12-02
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA.
Proc.Natl.Acad.Sci.USA, 117, 2020
3JA9
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BU of 3ja9 by Molmil
Structure of native human PCNA
分子名称: Proliferating cell nuclear antigen
著者Lau, W.C.Y, Li, Y, Zhang, Q, Huen, M.S.Y.
登録日2015-05-19
公開日2015-12-09
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (22 Å)
主引用文献Molecular architecture of the Ub-PCNA/Pol eta complex bound to DNA
Sci Rep, 5, 2015
3L0W
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BU of 3l0w by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position two
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6HVO
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BU of 6hvo by Molmil
Crystal structure of human PCNA in complex with three peptides of p12 subunit of human polymerase delta
分子名称: DNA polymerase delta subunit 4, Proliferating cell nuclear antigen, SULFATE ION
著者Gonzalez-Magana, A, Romano-Moreno, M, Rojas, A.L, Blanco, F.J, De Biasio, A.
登録日2018-10-11
公開日2019-01-23
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The p12 subunit of human polymerase delta uses an atypical PIP box for molecular recognition of proliferating cell nuclear antigen (PCNA).
J.Biol.Chem., 294, 2019
5DA7
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BU of 5da7 by Molmil
monomeric PCNA bound to a small protein inhibitor
分子名称: DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen, SULFATE ION, ...
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-19
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
3L10
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BU of 3l10 by Molmil
Structure of split monoubiquitinated PCNA with ubiquitin in position one
分子名称: Monoubiquitinated Proliferating cell nuclear antigen, Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-12-10
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.
Nat.Struct.Mol.Biol., 17, 2010
6K3A
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BU of 6k3a by Molmil
Crystal structure of human PCNA in complex with DNMT1 PIP box motif.
分子名称: Peptide from DNA (cytosine-5)-methyltransferase 1, Proliferating cell nuclear antigen
著者Jimenji, T, Kori, S, Arita, K.
登録日2019-05-17
公開日2019-06-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of PCNA in complex with DNMT1 PIP box reveals the basis for the molecular mechanism of the interaction.
Biochem.Biophys.Res.Commun., 516, 2019
5DAI
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BU of 5dai by Molmil
Proliferating cell nuclear antigen homolog 1 bound to FEN-1 peptide
分子名称: C-terminus of FEN-1 protein, DNA polymerase sliding clamp 1, SULFATE ION
著者Ladner, J.E, Altieri, A.S, Kelman, Z.
登録日2015-08-20
公開日2016-05-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A small protein inhibits proliferating cell nuclear antigen by breaking the DNA clamp.
Nucleic Acids Res., 44, 2016
7M5M
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BU of 7m5m by Molmil
PCNA bound to peptide mimetic
分子名称: N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5L
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BU of 7m5l by Molmil
PCNA bound to peptide mimetic with linker
分子名称: PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7M5N
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BU of 7m5n by Molmil
PCNA bound to peptide mimetic with linker
分子名称: 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2021-03-24
公開日2021-08-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献A cell permeable bimane-constrained PCNA-interacting peptide.
Rsc Chem Biol, 2, 2021
7KQ1
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BU of 7kq1 by Molmil
PCNA bound to truncated peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
7KQ0
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BU of 7kq0 by Molmil
PCNA bound to peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
6KNB
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BU of 6knb by Molmil
PolD-PCNA-DNA (form A)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2021-02-17
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
5AUJ
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BU of 5auj by Molmil
Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
分子名称: DNA polymerase sliding clamp
著者Watanabe, Y, Oyama, T.
登録日2015-04-21
公開日2016-04-27
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
To Be Published
6KNC
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BU of 6knc by Molmil
PolD-PCNA-DNA (form B)
分子名称: DNA polymerase D DP2 (DNA polymerase II large) subunit, DNA polymerase II small subunit, DNA polymerase sliding clamp 1, ...
著者Mayanagi, K, Oki, K, Miyazaki, N, Ishino, S, Yamagami, T, Iwasaki, K, Kohda, D, Morikawa, K, Shirai, T, Ishino, Y.
登録日2019-08-05
公開日2020-08-05
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (9.3 Å)
主引用文献Two conformations of DNA polymerase D-PCNA-DNA, an archaeal replisome complex, revealed by cryo-electron microscopy.
Bmc Biol., 18, 2020
5E0U
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BU of 5e0u by Molmil
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
分子名称: Cyclin-dependent kinase inhibitor 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
5E0V
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BU of 5e0v by Molmil
Human PCNA variant (S228I) complexed with FEN1 at 2.1 Angstroms
分子名称: Flap endonuclease 1, Proliferating cell nuclear antigen
著者Duffy, C.M, Hilbert, B.J, Kelch, B.A.
登録日2015-09-29
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.074 Å)
主引用文献A Disease-Causing Variant in PCNA Disrupts a Promiscuous Protein Binding Site.
J.Mol.Biol., 428, 2016
2HIK
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BU of 2hik by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
2HII
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BU of 2hii by Molmil
heterotrimeric PCNA sliding clamp
分子名称: PCNA1 (SSO0397), PCNA2 (SSO1047), PCNA3 (SSO0405)
著者Pascal, J.M, Tsodikov, O.V, Ellenberger, T.
登録日2006-06-29
公開日2006-11-07
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献A Flexible Interface between DNA Ligase and PCNA Supports Conformational Switching and Efficient Ligation of DNA.
Mol.Cell, 24, 2006
6S1O
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BU of 6s1o by Molmil
Human polymerase delta holoenzyme Conformer 3
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-06-19
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020
6AIG
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BU of 6aig by Molmil
Crystal structure of PCNA1 from Aeropyrum pernix
分子名称: DNA polymerase sliding clamp 1
著者Yamauchi, T, Kikuchi, M, Tsunoda, M.
登録日2018-08-23
公開日2018-09-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of PCNA1 from Aeropyrum pernix
To Be Published
6T7Y
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BU of 6t7y by Molmil
Structure of PCNA bound to cPIP motif of DP2 from P. abyssi
分子名称: DNA polymerase sliding clamp, cPIP motif from the DP2 large subunit of PolD
著者Madru, C, Raia, P, Hugonneau Beaufet, I, Delarue, M, Carroni, M, Sauguet, L.
登録日2019-10-23
公開日2020-03-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.
Nat Commun, 11, 2020
6CX2
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BU of 6cx2 by Molmil
S177G Mutant of Yeast PCNA
分子名称: Proliferating cell nuclear antigen
著者Powers, K.T.
登録日2018-04-02
公開日2018-04-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.101 Å)
主引用文献Identification of New Mutations at the PCNA Subunit Interface that Block Translesion Synthesis.
PLoS ONE, 11, 2016
6TNY
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BU of 6tny by Molmil
Processive human polymerase delta holoenzyme
分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ...
著者Lancey, C, Hamdan, S.M, De Biasio, A.
登録日2019-12-10
公開日2019-12-18
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the processive human Pol delta holoenzyme.
Nat Commun, 11, 2020

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