PDB: 141 件ウェブページステータス検索Chemie searchBIRD

---

5FTJ	Cryo-EM structure of human p97 bound to UPCDC30245 inhibitor 分子名称: 1-(3-(5-FLUORO-1H-INDOL-2-YL)PHENYL)PIPERIDIN-4-YL)(2-(4-ISOPROPYL-PIPERAZIN1-YL)ETHYL)-CARBAMATE, ADENOSINE-5'-DIPHOSPHATE, TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE 著者 Banerjee, S, Bartesaghi, A, Merk, A, Rao, P, Bulfer, S.L, Yan, Y, Green, N, Mroczkowski, B, Neitz, R.J, Wipf, P, Falconieri, V, Deshaies, R.J, Milne, J.L.S, Huryn, D, Arkin, M, Subramaniam, S. 登録日 2016-01-14 公開日 2016-01-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 2.3 A Resolution Cryo-Em Structure of Human P97 and Mechanism of Allosteric Inhibition Science, 351, 2016
5EPP	Structural Insights into the Interaction of p97 N-terminus Domain and VBM Motif in Rhomboid Protease, RHBDL4 分子名称: Rhomboid-related protein 4, Transitional endoplasmic reticulum ATPase 著者 Lim, J.J, Lee, Y, Ly, T.T, Kang, J.Y, Lee, J.-G, An, J.Y, Youn, H.-S, Park, K.R, Kim, T.G, Yang, J.K, Jun, Y, Eom, S.H. 登録日 2015-11-12 公開日 2016-09-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural insights into the interaction of p97 N-terminus domain and VBM in rhomboid protease, RHBDL4. Biochem.J., 473, 2016
5E7P	Crystal Structure of MSMEG_0858 (Uniprot A0QQS4), a AAA ATPase. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein Cdc48, GLYCEROL, ... 著者 Unciulac-Carp, M, Smith, P, Shuman, S. 登録日 2015-10-12 公開日 2016-08-24 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.507 Å) 主引用文献 Crystal Structure and Biochemical Characterization of a Mycobacterium smegmatis AAA-Type Nucleoside Triphosphatase Phosphohydrolase (Msm0858). J.Bacteriol., 198, 2016
5DYI	Structure of p97 N-D1 wild-type in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Tang, W.K, Xia, D. 登録日 2015-09-24 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.71 Å) 主引用文献 Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain. Sci Rep, 6, 2016
5DYG	Structure of p97 N-D1 L198W mutant in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Tang, W.K, Xia, D. 登録日 2015-09-24 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain. Sci Rep, 6, 2016
5C1B	p97-delta709-728 in complex with a UFD1-SHP peptide 分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 Characterization of an Additional Binding Surface on the p97 N-Terminal Domain Involved in Bipartite Cofactor Interactions. Structure, 24, 2016
5C1A	p97-N750D/R753D/M757D/Q760D in complex with ATP-gamma-S 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97. Structure, 24, 2016
5C19	p97 variant 2 in the apo state 分子名称: SULFATE ION, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97. Structure, 24, 2016
5C18	p97-delta709-728 in complex with ATP-gamma-S 分子名称: CHLORIDE ION, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2015-06-13 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural Basis of ATP Hydrolysis and Intersubunit Signaling in the AAA+ ATPase p97. Structure, 24, 2016
5B6C	Structural Details of Ufd1 binding to p97 分子名称: Peptide from Ubiquitin fusion degradation protein 1 homolog, Transitional endoplasmic reticulum ATPase 著者 Le, L.T.M, Yang, J.K. 登録日 2016-05-26 公開日 2017-01-04 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation PLoS ONE, 11, 2016
4RV0	Crystal structure of TN complex 分子名称: Nuclear protein localization protein 4 homolog, SULFATE ION, Transitional endoplasmic reticulum ATPase TER94 著者 Hao, Q, Jiao, S, Shi, Z.B, Zhou, Z.C. 登録日 2014-11-23 公開日 2015-11-25 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 Crystal structure of TN complex To be Published
4KOD	Structure of p97 N-D1 R155H mutant in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2013-05-11 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.96 Å) 主引用文献 Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
4KO8	Structure of p97 N-D1 R155H mutant in complex with ATPgS 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2013-05-11 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
4KLN	Structure of p97 N-D1 A232E mutant in complex with ATPgS 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Xia, D, Tang, W.K. 登録日 2013-05-07 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants. J.Biol.Chem., 288, 2013
4KDL	Crystal structure of p97/VCP N in complex with OTU1 UBXL 分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1 著者 Kim, S.J, Kim, E.E. 登録日 2013-04-25 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP). J.Biol.Chem., 289, 2014
4KDI	Crystal structure of p97/VCP N in complex with OTU1 UBXL 分子名称: Transitional endoplasmic reticulum ATPase, Ubiquitin thioesterase OTU1 著者 Kim, S.J, Kim, E.E. 登録日 2013-04-25 公開日 2014-03-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Structural Basis for Ovarian Tumor Domain-containing Protein 1 (OTU1) Binding to p97/Valosin-containing Protein (VCP). J.Biol.Chem., 289, 2014
3TIW	Crystal structure of p97N in complex with the C-terminus of gp78 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-08-22 公開日 2011-09-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97. J.Biol.Chem., 286, 2011
3QWZ	Crystal structure of FAF1 UBX-p97N-domain complex 分子名称: FAS-associated factor 1, Transitional endoplasmic reticulum ATPase 著者 Park, J.K, Jeon, H, Lee, J.J, Kim, K.H, Lee, K.J, Kim, E.E. 登録日 2011-02-28 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dissection of the interaction between FAF1 UBX and p97 To be Published
3QQ8	Crystal structure of p97-N in complex with FAF1-UBX 分子名称: CHLORIDE ION, FAS-associated factor 1, Transitional endoplasmic reticulum ATPase 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-02-15 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hierarchical Binding of Cofactors to the AAA ATPase p97. Structure, 19, 2011
3QQ7	Crystal Structure of the p97 N-terminal domain 分子名称: CHLORIDE ION, COBALT (II) ION, GLYCEROL, ... 著者 Haenzelmann, P, Schindelin, H. 登録日 2011-02-15 公開日 2011-06-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Hierarchical Binding of Cofactors to the AAA ATPase p97. Structure, 19, 2011
3QC8	Crystal Structure of FAF1 UBX Domain In Complex with p97/VCP N Domain Reveals The Conserved FcisP Touch-Turn Motif of UBX Domain Suffering Conformational Change 分子名称: FAS-associated factor 1, Transitional endoplasmic reticulum ATPase 著者 Kim, K.H, Kang, W, Suh, S.W, Yang, J.K. 登録日 2011-01-15 公開日 2011-07-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of FAF1 UBX domain in complex with p97/VCP N domain reveals a conformational change in the conserved FcisP touch-turn motif of UBX domain Proteins, 79, 2011
3J99	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIb) 分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... 著者 Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. 登録日 2014-12-05 公開日 2015-01-28 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
3J98	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State IIIa) 分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... 著者 Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. 登録日 2014-12-05 公開日 2015-01-28 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (8.4 Å) 主引用文献 Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
3J97	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State II) 分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... 著者 Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. 登録日 2014-12-05 公開日 2015-01-28 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015
3J96	Structure of 20S supercomplex determined by single particle cryoelectron microscopy (State I) 分子名称: Alpha-soluble NSF attachment protein, Synaptosomal-associated protein 25, Syntaxin-1A, ... 著者 Zhao, M, Wu, S, Cheng, Y, Brunger, A.T. 登録日 2014-12-05 公開日 2015-01-28 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Mechanistic insights into the recycling machine of the SNARE complex. Nature, 518, 2015

<123456>