PDB: 173 件ウェブページステータス検索Chemie searchBIRD

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4J35	Molecular Engineering of Organophosphate Hydrolysis Activity from a Weak Promiscuous Lactonase Template 分子名称: COBALT (II) ION, Phosphotriesterase, putative 著者 Sterner, R, Raushel, F, Meier, M, Rajendran, C, Malisi, C, Fox, N, Schlee, S, Barondeau, D, Cker, B.H. 登録日 2013-02-05 公開日 2013-07-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (1.783 Å) 主引用文献 Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135, 2013
4G2D	Crystal structure of the hyperthermophilic Sulfolobus islandicus PLL SisLac 分子名称: Aryldialkylphosphatase, COBALT (II) ION, FE (II) ION 著者 Gotthard, G, Hiblot, J, Elias, M, Chabriere, E. 登録日 2012-07-11 公開日 2012-10-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and enzymatic characterization of the lactonase SisLac from Sulfolobus islandicus Plos One, 7, 2012
4J5N	Crystal Structure of a Deinococcus radiodurans PTE-like lactonase (drPLL) mutant Y28L/D71N/E101G/E179D/V235L/L270M 分子名称: COBALT (II) ION, Phosphotriesterase, putative 著者 Meier, M.M, Rajendran, C, Malisi, C, Fox, N.G, Xu, C, Schlee, S, Barondeau, D.P, Hocker, B, Sterner, R, Raushel, F.M. 登録日 2013-02-08 公開日 2013-07-24 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template. J.Am.Chem.Soc., 135, 2013
4H9V	Structure of Geobacillus kaustophilus lactonase, mutant E101G/R230C with Zn2+ 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.971 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
4LEF	Crystal structure of PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI complexed with phosphate in active site 分子名称: PHOSPHATE ION, Phosphotriesterase homology protein, ZINC ION, ... 著者 Fedorov, A.A, Fedorov, E.V, Xiang, D.F, Raushel, F.M, Almo, S.C. 登録日 2013-06-25 公開日 2014-06-25 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.842 Å) 主引用文献 Crystal structure of PHOSPHOTRIESTERASE HOMOLOGY PROTEIN FROM ESCHERICHIA COLI complexed with phosphate in active site To be Published
4H9T	Structure of Geobacillus kaustophilus lactonase, mutant E101N with bound N-butyryl-DL-homoserine lactone 分子名称: FE (III) ION, MANGANESE (II) ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-24 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
6FQE	Phosphotriesterase PTE_A53_4 分子名称: (4~{S},6~{R})-2,2,6-trimethyl-1,3-dioxan-4-ol, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-02-14 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Phosphotriesterase PTE_A53_4 To Be Published
6FS3	Phosphotriesterase PTE_A53_1 分子名称: (2~{S})-2-methylpentanedioic acid, FORMIC ACID, Parathion hydrolase, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-02-19 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structures of Bacterail Phosphotriesterase variant with high catalytic activity towards organophosphate nerve agents developed by use of structure-based design and molecular evolution To Be Published
4GY0	Round 18 Arylesterase Variant of Phosphotriesterase 分子名称: ZINC ION, arylesterase variant of phosphotriesterase 著者 Jackson, C.J, Tokuriki, N, Tawfik, D.S. 登録日 2012-09-05 公開日 2013-08-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme Nat Commun, 3, 2012
4HA0	Structure of Geobacillus kaustophilus lactonase, mutant R230D with Zn2+ 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.902 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
4H9U	Structure of Geobacillus kaustophilus lactonase, wild-type with Zn2+ 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
4H9X	Structure of Geobacillus kaustophilus lactonase, mutant E101G/R230C/D266N with Zn2+ and bound N-butyryl-DL-homoserine lactone 分子名称: FE (III) ION, HYDROXIDE ION, N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.201 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
6GBJ	Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions 分子名称: 1,2-ETHANEDIOL, FORMIC ACID, Parathion hydrolase, ... 著者 Khersonsky, O, Lipsh, R, Avizemer, Z, Goldsmith, M, Ashani, Y, Leader, H, Dym, O, Rogotner, S, Trudeau, D, Tawfik, D.S, Fleishman, S.J. 登録日 2018-04-15 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72, 2018
4H9Y	Structure of Geobacillus kaustophilus lactonase, mutant E101N with Zn2+ 分子名称: FE (III) ION, HYDROXIDE ION, Phosphotriesterase, ... 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.085 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
4H9Z	Structure of Geobacillus kaustophilus lactonase, mutant E101N with Mn2+ 分子名称: FE (III) ION, MANGANESE (II) ION, Phosphotriesterase 著者 Xue, B, Chow, J.Y, Yew, W.S, Robinson, R.C. 登録日 2012-09-25 公開日 2012-11-07 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural evidence of a productive active site architecture for an evolved quorum-quenching GKL lactonase. Biochemistry, 52, 2013
6FFW	Phosphotriesterase PTE_A53_5 分子名称: (4~{S},6~{R})-2,2,6-trimethyl-1,3-dioxan-4-ol, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-01-09 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.495 Å) 主引用文献 Phosphotriesterase PTE_A53_5 To Be Published
4KEV	Crystal structure of SsoPox W263L 分子名称: Aryldialkylphosphatase, COBALT (II) ION, FE (II) ION 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
4KER	Crystal structure of SsoPox W263V 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
6G1J	Phosphotriesterase PTE_C23M_1 分子名称: 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-03-21 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Phosphotriesterase PTE_C23M_1 To Be Published
4KEU	Crystal structure of SsoPox W263M 分子名称: 1,2-ETHANEDIOL, Aryldialkylphosphatase, COBALT (II) ION, ... 著者 Gotthard, G, Hiblot, J, Chabriere, E, Elias, M. 登録日 2013-04-26 公開日 2013-10-02 最終更新日 2013-11-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox. Plos One, 8, 2013
6FRZ	Phosphotriesterase PTE_A53_7 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5-methylcyclohexane-1,1,3,3-tetrol, DI(HYDROXYETHYL)ETHER, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-02-18 公開日 2019-03-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Phosphotriesterase PTE_A53_7 To Be Published
6FWE	Phosphotriesterase PTE_C23_6 分子名称: 1-[methoxy(methyl)phosphoryl]oxyethane, 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-03-06 公開日 2019-03-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.774 Å) 主引用文献 Phosphotriesterase PTE_C23_6 To Be Published
6GBK	Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FORMIC ACID, Parathion hydrolase, ... 著者 Khersonsky, O, Lipsh, R, Avizemer, Z, Goldsmith, M, Ashani, Y, Leader, H, Dym, O, Rogotner, S, Trudeau, D, Tawfik, D.S, Fleishman, S.J. 登録日 2018-04-15 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72, 2018
6GBL	Repertoires of functionally diverse enzymes through computational design at epistatic active-site positions 分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, FORMIC ACID, ... 著者 Khersonsky, O, Lipsh, R, Avizemer, Z, Goldsmith, M, Ashani, Y, Leader, H, Dym, O, Rogotner, S, Trudeau, D, Tawfik, D.S, Fleishman, S.J. 登録日 2018-04-15 公開日 2018-10-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Automated Design of Efficient and Functionally Diverse Enzyme Repertoires. Mol. Cell, 72, 2018
6FU6	Phosphotriesterase PTE_C23_2 分子名称: FORMIC ACID, POLYACRYLIC ACID, Parathion hydrolase, ... 著者 Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. 登録日 2018-02-26 公開日 2019-03-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Phosphotriesterase PTE_A53_4 To Be Published

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