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2WQ7
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Structure of the 6-4 photolyase of D. melanogaster in complex with the non-natural N4-methyl T(6-4)C lesion
分子名称: 5'-D(*AP*CP*AP*GP*CP*GP*GP*TDYP*ZP*GP* CP*AP*AP*GP*T)-3', 5'-D(*TP*AP*CP*CP*TP*GP*CP*GP*AP*CP* CP*GP*CP*TP*G)-3', FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Glas, A.F, Kaya, E, Schneider, S, Maul, M.J, Carell, T.
登録日2009-08-14
公開日2010-02-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献DNA (6-4) Photolyases Reduce Dewar Isomers for Isomerization Into (6-4) Lesions.
J.Am.Chem.Soc., 132, 2010
4MLP
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Mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase
分子名称: Cryptochrome-2, N-[(2S)-3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(furan-2-ylmethyl)methanesulfonamide
著者Nangle, S, Xing, W, Zheng, N.
登録日2013-09-06
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.943 Å)
主引用文献Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase.
Cell Res., 23, 2013
2J09
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Thermus DNA photolyase with FMN antenna chromophore
分子名称: CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, FLAVIN MONONUCLEOTIDE, ...
著者Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O.
登録日2006-08-01
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
Chembiochem, 7, 2006
2J07
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Thermus DNA photolyase with 8-HDF antenna chromophore
分子名称: 8-HYDROXY-10-(D-RIBO-2,3,4,5-TETRAHYDROXYPENTYL)-5-DEAZAISOALLOXAZINE, CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, ...
著者Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O.
登録日2006-08-01
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
Chembiochem, 7, 2006
2J08
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Thermus DNA photolyase with 8-Iod-riboflavin antenna chromophore
分子名称: 1-DEOXY-1-(8-IODO-7-METHYL-2,4-DIOXO-3,4-DIHYDROBENZO[G]PTERIDIN-10(2H)-YL)-D-RIBITOL, CHLORIDE ION, DEOXYRIBODIPYRIMIDINE PHOTO-LYASE, ...
著者Klar, T, Kaiser, G, Hennecke, U, Carell, T, Batschauer, A, Essen, L.-O.
登録日2006-08-01
公開日2007-05-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Natural and Non-Natural Antenna Chromophores in the DNA Photolyase from Thermus Thermophilus
Chembiochem, 7, 2006
2J4D
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BU of 2j4d by Molmil
Cryptochrome 3 from Arabidopsis thaliana
分子名称: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, CRYPTOCHROME DASH, FLAVIN-ADENINE DINUCLEOTIDE
著者Klar, T, Pokorny, R, Batschauer, A, Essen, L.-O.
登録日2006-08-28
公開日2007-06-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cryptochrome 3 from Arabidopsis Thaliana: Structural and Functional Analysis of its Complex with a Folate Light Antenna
J.Mol.Biol., 366, 2007
2IJG
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Crystal Structure of cryptochrome 3 from Arabidopsis thaliana
分子名称: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, Cryptochrome DASH, chloroplast/mitochondrial, ...
著者Huang, Y, Deisenhofer, J.
登録日2006-09-29
公開日2006-11-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of cryptochrome 3 from Arabidopsis thaliana and its implications for photolyase activity
Proc.Natl.Acad.Sci.Usa, 103, 2006
3CVY
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Drosophila melanogaster (6-4) photolyase bound to repaired ds DNA
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*DTP*DTP*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and mechanism of a DNA (6-4) photolyase.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CVV
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Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion and F0 cofactor
分子名称: 1,2-ETHANEDIOL, 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), ...
著者Glas, A.F, Maul, M.J, Cryle, M.J, Barends, T.R.M, Schneider, S, Kaya, E, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2009-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes.
Proc.Natl.Acad.Sci.USA, 106, 2009
3CVX
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Drosophila melanogaster (6-4) photolyase H369M mutant bound to ds DNA with a T-T (6-4) photolesion
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2009-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and mechanism of a coenzyme F0 accelerated (6-4) photolyase from the fruit fly
To be Published
3CVU
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BU of 3cvu by Molmil
Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion
分子名称: DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2008-11-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and mechanism of a DNA (6-4) photolyase.
Angew.Chem.Int.Ed.Engl., 47, 2008
3CVW
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BU of 3cvw by Molmil
Drosophila melanogaster (6-4) photolyase H365N mutant bound to ds DNA with a T-T (6-4) photolesion and cofactor F0
分子名称: 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), ...
著者Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T.
登録日2008-04-20
公開日2009-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure and mechanism of a cofactor f0 accelerated (6-4) photolyase from the fruit fly
To be Published
3FY4
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(6-4) Photolyase Crystal Structure
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-4 photolyase, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Hitomi, K, Arvai, A.S, Tainer, J.A, Getzoff, E.D.
登録日2009-01-21
公開日2009-04-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes.
Proc.Natl.Acad.Sci.USA, 106, 2009
6KX8
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BU of 6kx8 by Molmil
Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX7
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BU of 6kx7 by Molmil
Crystal structure of mouse Cryptochrome 1 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX5
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BU of 6kx5 by Molmil
Crystal structure of mouse Cryptochrome 1 in complex with KL044 compound
分子名称: 2-carbazol-9-yl-N-(2-chloranyl-6-cyano-phenyl)ethanamide, Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
1NP7
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Crystal Structure Analysis of Synechocystis sp. PCC6803 cryptochrome
分子名称: DNA photolyase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
著者Brudler, R, Hitomi, K, Daiyasu, H, Toh, H, Kucho, K, Ishiura, M, Kanehisa, M, Roberts, V.A, Todo, T, Tainer, J.A, Getzoff, E.D.
登録日2003-01-17
公開日2003-01-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of a new cryptochrome class: structure, function, and evolution
Mol.Cell, 11, 2003
1OWM
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DATA1:DNA photolyase / received X-rays dose 1.2 exp15 photons/mm2
分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
著者Komori, H, Adachi, S, Miki, K, Eker, A, Kort, R.
登録日2003-03-28
公開日2004-04-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA apophotolyase from Anacystis nidulans: 1.8 A structure, 8-HDF reconstitution and X-ray-induced FAD reduction.
Acta Crystallogr.,Sect.D, 60, 2004
1OWN
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DATA3:DNA photolyase / received X-rays dose 4.8 exp15 photons/mm2
分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
著者Komori, H, Adachi, S, Miki, K, Eker, A, Kort, R.
登録日2003-03-28
公開日2004-04-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA apophotolyase from Anacystis nidulans: 1.8 A structure, 8-HDF reconstitution and X-ray-induced FAD reduction.
Acta Crystallogr.,Sect.D, 60, 2004
6KX6
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Crystal structure of mouse Cryptochrome 1 in complex with KL101 compound
分子名称: Cryptochrome-1, ~{N}-[2-(2,4-dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3,4-dimethyl-benzamide
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
6KX4
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BU of 6kx4 by Molmil
Crystal structure of mouse Cryptochrome 1 apo form
分子名称: Cryptochrome-1
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
1OWP
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BU of 1owp by Molmil
DATA6:photoreduced DNA pholyase / received X-rays dose 4.8 exp15 photons/mm2
分子名称: Deoxyribodipyrimidine photolyase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
著者Komori, H, Adachi, S, Miki, K, Eker, A, Kort, R.
登録日2003-03-28
公開日2004-04-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献DNA apophotolyase from Anacystis nidulans: 1.8 A structure, 8-HDF reconstitution and X-ray-induced FAD reduction.
Acta Crystallogr.,Sect.D, 60, 2004
6LZ7
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Tetrameric structure of ZmCRY1a PHR domain
分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE
著者Shao, K, Zhang, X, Zhang, P.
登録日2020-02-18
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.59936166 Å)
主引用文献The oligomeric structures of plant cryptochromes.
Nat.Struct.Mol.Biol., 27, 2020
7D0N
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Crystal structure of mouse CRY2 apo form
分子名称: Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2020-09-11
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
7DLI
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Crystal structure of mouse CRY1 in complex with KL001 compound
分子名称: 1,2-ETHANEDIOL, Cryptochrome-1, N-[(2R)-3-carbazol-9-yl-2-oxidanyl-propyl]-N-(furan-2-ylmethyl)methanesulfonamide
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2020-11-27
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021

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