3OR6
 
 | | On the structural basis of modal gating behavior in K+channels - E71Q | | 分子名称: | POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ... | | 著者 | Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Perozo, E. | | 登録日 | 2010-09-06 | | 公開日 | 2011-01-05 | | 最終更新日 | 2018-08-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
|
|
4LBE
 | | Structure of KcsA with R122A mutation | | 分子名称: | DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ... | | 著者 | Nimigean, C.M, Posson, D.J, McCoy, J.M. | | 登録日 | 2013-06-20 | | 公開日 | 2013-10-30 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | | 主引用文献 | Molecular interactions involved in proton-dependent gating in KcsA potassium channels.
J.Gen.Physiol., 142, 2013
|
|
3OGC
 | | KcsA E71A variant in presence of Na+ | | 分子名称: | SODIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... | | 著者 | McCoy, J.G, Nimigean, C.M. | | 登録日 | 2010-08-16 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4LCU
 | | Structure of KcsA with E118A mutation | | 分子名称: | DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ... | | 著者 | Nimigean, C.M, Posson, D.J, McCoy, J.M. | | 登録日 | 2013-06-23 | | 公開日 | 2013-10-30 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.752 Å) | | 主引用文献 | Molecular interactions involved in proton-dependent gating in KcsA potassium channels.
J.Gen.Physiol., 142, 2013
|
|
3PJS
 | | Mechanism of Activation Gating in the Full-Length KcsA K+ Channel | | 分子名称: | FAB heavy chain, FAB light chain, Voltage-gated potassium channel | | 著者 | Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E. | | 登録日 | 2010-11-10 | | 公開日 | 2011-07-06 | | 最終更新日 | 2011-08-03 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4LTP
 | | Bacterial sodium channel in high calcium, I222 space group, crystal 2 | | 分子名称: | CALCIUM ION, Ion transport protein | | 著者 | Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L. | | 登録日 | 2013-07-23 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
|
|
3RVZ
 | | Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.8 A) | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2011-05-06 | | 公開日 | 2011-07-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
|
|
3RW0
 | | Crystal structure of the NavAb voltage-gated sodium channel (Met221Cys, 2.95 A) | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2011-05-06 | | 公開日 | 2011-07-13 | | 最終更新日 | 2011-07-27 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
|
|
4LTO
 | | Bacterial sodium channel in high calcium, I222 space group | | 分子名称: | CALCIUM ION, Ion transport protein, NICKEL (II) ION | | 著者 | Shaya, D, Findeisen, F, Abderemane-Ali, F, Arrigoni, C, Wong, S, Reddy Nurva, S, Loussouarn, G, Minor, D.L. | | 登録日 | 2013-07-23 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Structure of a prokaryotic sodium channel pore reveals essential gating elements and an outer ion binding site common to eukaryotic channels.
J.Mol.Biol., 426, 2014
|
|
3RVY
 | | Crystal structure of the NavAb voltage-gated sodium channel (Ile217Cys, 2.7 A) | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | | 著者 | Payandeh, J, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2011-05-06 | | 公開日 | 2011-07-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The crystal structure of a voltage-gated sodium channel.
Nature, 475, 2011
|
|
4F4L
 | | Open Channel Conformation of a Voltage Gated Sodium Channel | | 分子名称: | Ion transport protein | | 著者 | McCusker, E.C, Bagneris, C, Naylor, C.E, Cole, A.R, D'Avanzo, N, Nichols, C.G, Wallace, B.A. | | 登録日 | 2012-05-10 | | 公開日 | 2012-10-03 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | Structure of a bacterial voltage-gated sodium channel pore reveals mechanisms of opening and closing.
Nat Commun, 3, 2012
|
|
4DXW
 | | Crystal structure of NavRh, a voltage-gated sodium channel | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Zhang, X, Ren, W.L, Yan, C.Y, Wang, J.W, Yan, N. | | 登録日 | 2012-02-28 | | 公開日 | 2012-05-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.052 Å) | | 主引用文献 | Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
Nature, 486, 2012
|
|
4H37
 | | Crystal structure of a voltage-gated K+ channel pore domain in a closed state in lipid membranes | | 分子名称: | Lmo2059 protein, POTASSIUM ION | | 著者 | Santos, J.S, Asmar-Rovira, G.A, Han, G.W, Liu, W, Syeda, R, Cherezov, V, Baker, K.A, Stevens, R.C, Montal, M. | | 登録日 | 2012-09-13 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes.
J.Biol.Chem., 287, 2012
|
|
4H33
 | | Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes, tetragonal crystal form | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Lmo2059 protein, POTASSIUM ION | | 著者 | Santos, J.S, Asmar-Rovira, G.A, Han, G.W, Liu, W, Syeda, R, Cherezov, V, Baker, K.A, Stevens, R.C, Montal, M. | | 登録日 | 2012-09-13 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal Structure of a Voltage-gated K+ Channel Pore Module in a Closed State in Lipid Membranes.
J.Biol.Chem., 287, 2012
|
|
4EKW
 | | Crystal structure of the NavAb voltage-gated sodium channel (wild-type, 3.2 A) | | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein, PHOSPHATE ION | | 著者 | Payandeh, J, Gamal El-Din, T.M, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2012-04-10 | | 公開日 | 2012-05-16 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Crystal structure of a voltage-gated sodium channel in two potentially inactivated states.
Nature, 486, 2012
|
|
5K47
 | | CryoEM structure of the human Polycystin-2/PKD2 TRP channel | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | | 著者 | Pike, A.C.W, Grieben, M, Shintre, C.A, Tessitore, A, Shrestha, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2016-05-20 | | 公開日 | 2016-08-24 | | 最終更新日 | 2020-10-21 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2).
Nat. Struct. Mol. Biol., 24, 2017
|
|
6YZ0
 | | Full length Open-form Sodium Channel NavMs F208L in complex with Cannabidiol (CBD) | | 分子名称: | 2-[(1R,2R,5S)-5-methyl-2-(prop-1-en-2-yl)cyclohexyl]-5-pentylbenzene-1,3-diol, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Sait, L.G, Hollingworth, D, Wallace, B.A. | | 登録日 | 2020-05-06 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cannabidiol interactions with voltage-gated sodium channels.
Elife, 9, 2020
|
|
5KMD
 | | Structure of CavAb in complex with amlodipine | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-26 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
5KLB
 | | Crystal structure of the CavAb voltage-gated calcium channel(wild-type, 2.7A) | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CALCIUM ION, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-23 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
6Z8C
 | | Crystal Structure of the Voltage-Gated Sodium Channel NavMs (F208L) in complex with N-desmethyltamoxifen (3.2 A resolution) | | 分子名称: | 2-[4-[(~{Z})-1,2-diphenylbut-1-enyl]phenoxy]-~{N}-methyl-ethanamine, DODECAETHYLENE GLYCOL, HEGA-10, ... | | 著者 | Sula, A, Hollingworth, D, Wallace, B.A. | | 登録日 | 2020-06-02 | | 公開日 | 2021-02-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | A tamoxifen receptor within a voltage-gated sodium channel.
Mol.Cell, 81, 2021
|
|
5KLS
 | | Structure of CavAb in complex with Br-dihydropyridine derivative UK-59811 | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-25 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
5KMH
 | | Structure of CavAb in complex with Br-verapamil | | 分子名称: | (2~{R})-2-(2-bromophenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-propan-2-yl-pentanenitrile, 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-27 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
5KMF
 | | Structure of CavAb in complex with nimodipine | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-26 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
5KLG
 | | Structure of CavAb(W195Y) in complex with Br-dihydropyridine derivative UK-59811 | | 分子名称: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, CALCIUM ION, Ion transport protein, ... | | 著者 | Tang, L, Gamal EL-Din, T.M, Swanson, T.M, Pryde, D.C, Scheuer, T, Zheng, N, Catterall, W.A. | | 登録日 | 2016-06-24 | | 公開日 | 2016-08-31 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural basis for inhibition of a voltage-gated Ca(2+) channel by Ca(2+) antagonist drugs.
Nature, 537, 2016
|
|
7A6U
 | | Cryo-EM structure of the cytoplasmic domain of human TRPC6 | | 分子名称: | Short transient receptor potential channel 6, UNKNOWN ATOM OR ION | | 著者 | Grieben, M, Pike, A.C.W, Wang, D, Mukhopadhyay, S.M.M, Chalk, R, Marsden, B.D, Burgess-Brown, N.A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | | 登録日 | 2020-08-26 | | 公開日 | 2020-09-30 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | | 主引用文献 | Cryo-EM structure of the cytoplasmic domain of human TRPC6
TO BE PUBLISHED
|
|
