4MT7
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4F7H
| The crystal structure of kindlin-2 pleckstrin homology domain in free form | 分子名称: | Fermitin family homolog 2, S,R MESO-TARTARIC ACID | 著者 | Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. | 登録日 | 2012-05-16 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
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4UUK
| Human dynamin 1 K44A superconstricted polymer stabilized with GTP strand 2 | 分子名称: | DYNAMIN-1 | 著者 | Sundborger, A.C, Fang, S, Heymann, J.A, Ray, P, Chappie, J.S, Hinshaw, J.E. | 登録日 | 2014-07-29 | 公開日 | 2014-08-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (12.5 Å) | 主引用文献 | A Dynamin Mutant Defines a Superconstricted Prefission State. Cell Rep., 8, 2014
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2R09
| Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor | 分子名称: | 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... | 著者 | DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G. | 登録日 | 2007-08-17 | 公開日 | 2007-12-04 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors. Mol.Cell, 28, 2007
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6U3G
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4XH3
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6DLV
| Cryo-EM of the GTP-bound human dynamin-1 polymer assembled on the membrane in the super constricted state | 分子名称: | Dynamin-1 | 著者 | Kong, L, Wang, H, Fang, S, Canagarajah, B, Kehr, A.D, Rice, W.J, Hinshaw, J.E. | 登録日 | 2018-06-02 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (10.1 Å) | 主引用文献 | Cryo-EM of the dynamin polymer assembled on lipid membrane. Nature, 560, 2018
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2R0D
| Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor | 分子名称: | Cytohesin-3, DI(HYDROXYETHYL)ETHER, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, ... | 著者 | DiNitto, J.P, Delprato, A, Gabe Lee, M.T, Cronin, T.C, Huang, S, Guilherme, A, Czech, M.P, Lambright, D.G. | 登録日 | 2007-08-18 | 公開日 | 2007-12-04 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural Basis and Mechanism of Autoregulation in 3-Phosphoinositide-Dependent Grp1 Family Arf GTPase Exchange Factors. Mol.Cell, 28, 2007
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6E31
| Crystal structure of RIAM in an autoinhibited configuration. | 分子名称: | Rap1-interacting adapter molecule | 著者 | Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J. | 登録日 | 2018-07-12 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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3HK0
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3HW2
| Crystal structure of the SifA-SKIP(PH) complex | 分子名称: | Pleckstrin homology domain-containing family M member 2, Protein sifA | 著者 | Diacovich, L, Dumont, A, Lafitte, D, Soprano, E, Guilhon, A.-A, Bignon, C, Gorvel, J.-P, Bourne, Y, Meresse, S. | 登録日 | 2009-06-17 | 公開日 | 2009-11-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis J.Biol.Chem., 284, 2009
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4NSW
| Crystal structure of the BAR-PH domain of ACAP1 | 分子名称: | Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 | 著者 | Pang, X, Zhang, K, Ma, J, Zhou, Q, Sun, F. | 登録日 | 2013-11-29 | 公開日 | 2014-10-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A PH Domain in ACAP1 Possesses Key Features of the BAR Domain in Promoting Membrane Curvature Dev.Cell, 31, 2014
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6FSF
| Crystal structure of the tandem PX-PH-domains of Bem3 from Saccharomyces cerevisiae | 分子名称: | GTPase-activating protein BEM3 | 著者 | Ali, I, Eu, S, Koch, D, Bleimling, N, Goody, R.S, Mueller, M.P. | 登録日 | 2018-02-19 | 公開日 | 2018-05-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5JJD
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4Y94
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4Y93
| Crystal structure of the PH-TH-kinase construct of Bruton's tyrosine kinase (Btk) | 分子名称: | 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide, CALCIUM ION, Non-specific protein-tyrosine kinase,Non-specific protein-tyrosine kinase, ... | 著者 | Wang, Q, Kuriyan, J. | 登録日 | 2015-02-16 | 公開日 | 2015-03-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.695 Å) | 主引用文献 | Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife, 4, 2015
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5A3F
| Crystal structure of the dynamin tetramer | 分子名称: | DYNAMIN 3 | 著者 | Reubold, T.F, Faelber, K, Plattner, N, Posor, Y, Branz, K, Curth, U, Schlegel, J, Anand, R, Manstein, D.J, Noe, F, Haucke, V, Daumke, O, Eschenburg, S. | 登録日 | 2015-05-29 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Crystal Structure of the Dynamin Tetramer Nature, 525, 2015
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5L81
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5C5B
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7C3M
| Structure of FERM protein | 分子名称: | Fermitin family homolog 3,Fermitin family homolog 3,Fermitin family homolog 3 | 著者 | Bu, W, Loh, Z.Y, Jin, S, Basu, S, Ero, R, Park, J.E, Yan, X, Wang, M, Sze, S.K, Tan, S.M, Gao, Y.G. | 登録日 | 2020-05-13 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural basis of human full-length kindlin-3 homotrimer in an auto-inhibited state. Plos Biol., 18, 2020
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3KSY
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3FEH
| Crystal structure of full length centaurin alpha-1 | 分子名称: | Centaurin-alpha-1, UNKNOWN ATOM OR ION, ZINC ION | 著者 | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-29 | 公開日 | 2008-12-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin {alpha}1. Proc.Natl.Acad.Sci.USA, 107, 2010
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3FM8
| Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target) | 分子名称: | Centaurin-alpha-1, Kinesin-like protein KIF13B, SULFATE ION, ... | 著者 | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-12-19 | 公開日 | 2009-08-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. Proc.Natl.Acad.Sci.USA, 107, 2010
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3CXB
| Crystal Structure of sifa and skip | 分子名称: | Pleckstrin homology domain-containing family M member 2, Protein sifA | 著者 | Huang, Z, Chai, J. | 登録日 | 2008-04-24 | 公開日 | 2008-12-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation Cell Host Microbe, 4, 2008
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6YYK
| Crystal Structure of 1,5-dimethylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C | 分子名称: | 1,5-dimethyl-3~{H}-indol-2-one, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... | 著者 | Brear, P, Wagstaff, J, Hyvonen, M. | 登録日 | 2020-05-05 | 公開日 | 2021-05-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Optimising crystallographic systems for structure-guided drug discovery To Be Published
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