8D11
 
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8DE8
 | | Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPA mixed micelles | | 分子名称: | (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, POTASSIUM ION, Potassium channel, ... | | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | | 登録日 | 2022-06-20 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (2.82 Å) | | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.
Nat Commun, 14, 2023
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8DE9
 | | Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPE mixed micelles | | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, POTASSIUM ION, Potassium channel, ... | | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | | 登録日 | 2022-06-20 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.
Nat Commun, 14, 2023
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8DE7
 | | Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM detergent | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, Potassium channel, ... | | 著者 | Schmidpeter, P.A.M, Nimigean, C.M, Riegelhaupt, P.M. | | 登録日 | 2022-06-20 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.
Nat Commun, 14, 2023
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8DK6
 | | Structure of hepatitis C virus envelope N-terminal truncated glycoprotein 2 (E2) (residues 456-713) from J6 genotype | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A12 Fab Heavy chain, 2A12 Fab light chain, ... | | 著者 | Kumar, A, Rohe, T, Elrod, E.J, Khan, A.G, Dearborn, A.D, Kissinger, R, Grakoui, A, Marcotrigiano, J. | | 登録日 | 2022-07-03 | | 公開日 | 2023-03-29 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Regions of hepatitis C virus E2 required for membrane association.
Nat Commun, 14, 2023
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1XBO
 | | PTP1B complexed with Isoxazole Carboxylic Acid | | 分子名称: | 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | | 著者 | Zhao, H, Liu, G, Xin, Z, Serby, M, Pei, Z, Szczepankiewicz, B.G, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Lubben, T.H, Ballaron, S.J, Hassach, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | | 登録日 | 2004-08-31 | | 公開日 | 2004-10-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.
Bioorg.Med.Chem.Lett., 14, 2004
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2FSY
 | | Bacteriophage HK97 Pepsin-treated Expansion Intermediate IV | | 分子名称: | major capsid protein | | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | 登録日 | 2006-01-23 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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1WAU
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8EAZ
 | | HOIL-1/E2-Ub/Ub transthiolation complex | | 分子名称: | RanBP-type and C3HC4-type zinc finger-containing protein 1, Ubiquitin, Ubiquitin-conjugating enzyme E2 L3, ... | | 著者 | Wang, X.S, Cotton, T.R, Lechtenberg, B.C. | | 登録日 | 2022-08-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | | 主引用文献 | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
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2FRP
 | | Bacteriophage HK97 Expansion Intermediate IV | | 分子名称: | Major capsid protein | | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | 登録日 | 2006-01-19 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (7.5 Å) | | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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8EB0
 | | RNF216/E2-Ub/Ub transthiolation complex | | 分子名称: | E3 ubiquitin-protein ligase RNF216, SULFATE ION, Ubiquitin, ... | | 著者 | Cotton, T.R, Wang, X.S, Lechtenberg, B.C. | | 登録日 | 2022-08-30 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | The unifying catalytic mechanism of the RING-between-RING E3 ubiquitin ligase family.
Nat Commun, 14, 2023
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2FT1
 | | Bacteriophage HK97 Head II | | 分子名称: | major capsid protein | | 著者 | Gan, L, Speir, J.A, Conway, J.F, Lander, G, Cheng, N, Firek, B.A, Hendrix, R.W, Duda, R.L, Liljas, L, Johnson, J.E. | | 登録日 | 2006-01-23 | | 公開日 | 2006-02-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Capsid Conformational Sampling in HK97 Maturation Visualized by X-Ray Crystallography and Cryo-EM.
Structure, 14, 2006
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1WA3
 | | Mechanism of the Class I KDPG aldolase | | 分子名称: | 2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE ALDOLASE, PYRUVIC ACID, SULFATE ION | | 著者 | Fullerton, S.W.B, Griffiths, J.S, Merkel, A.B, Wymer, N.J, Hutchins, M.J, Fierke, C.A, Toone, E.J, Naismith, J.H. | | 登録日 | 2004-10-22 | | 公開日 | 2005-01-26 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism of the Class I Kdpg Aldolase.
Bioorg.Med.Chem., 14, 2006
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1WBH
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2ICW
 | | Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Wang, L, Zhao, Y, Li, H. | | 登録日 | 2006-09-13 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Nat.Struct.Mol.Biol., 14, 2007
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8E31
 | | Purification of Enterovirus A71, strain 4643, WT capsid | | 分子名称: | Genome polyprotein, VP1, VP3 | | 著者 | Catching, A, Capponi, S, Andino, R. | | 登録日 | 2022-08-16 | | 公開日 | 2023-08-30 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | A tradeoff between enterovirus A71 particle stability and cell entry.
Nat Commun, 14, 2023
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8DPU
 | | The crystal structure of the IL-11 signalling complex | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... | | 著者 | Metcalfe, R.D, Aizel, K, Griffin, M.D.W. | | 登録日 | 2022-07-17 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.78 Å) | | 主引用文献 | Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant.
Nat Commun, 14, 2023
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8EP2
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8EP9
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8EHB
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1XO3
 | | Solution Structure of Ubiquitin like protein from Mus Musculus | | 分子名称: | RIKEN cDNA 2900073H19 | | 著者 | Singh, S, Tonelli, M, Tyler, R.C, Bahrami, A, Lee, M.S, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2004-10-05 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1.
Protein Sci., 14, 2005
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2J9I
 | | Lengsin is a survivor of an ancient family of class I glutamine synthetases in eukaryotes that has undergone evolutionary re- engineering for a tissue-specific role in the vertebrate eye lens. | | 分子名称: | GLUTAMATE-AMMONIA LIGASE DOMAIN-CONTAINING PROTEIN 1 | | 著者 | Wyatt, K, White, H.E, Wang, L, Bateman, O.A, Slingsby, C, Orlova, E.V, Wistow, G. | | 登録日 | 2006-11-09 | | 公開日 | 2006-12-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (17 Å) | | 主引用文献 | Lengsin is a Survivor of an Ancient Family of Class I Glutamine Synthetases Re-Engineered by Evolution for a Role in the Vertebrate Lens.
Structure, 14, 2006
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6J15
 | | Complex structure of GY-5 Fab and PD-1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GY-5 heavy chain Fab, ... | | 著者 | Chen, D, Tan, S, Zhang, H, Wang, H, Chai, Y, Qi, J, Yan, J, Gao, G.F. | | 登録日 | 2018-12-27 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The FG Loop of PD-1 Serves as a "Hotspot" for Therapeutic Monoclonal Antibodies in Tumor Immune Checkpoint Therapy.
Iscience, 14, 2019
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1X7A
 | | Porcine Factor IXa Complexed to 1-{3-[amino(imino)methyl]phenyl}-N-[4-(1H-benzimidazol-1-yl)-2-fluorophenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide | | 分子名称: | 1-{3-[AMINO(IMINO)METHYL]PHENYL}-N-[4-(1H-BENZIMIDAZOL-1-YL)-2-FLUOROPHENYL]-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-5-CARBOXAMIDE, Coagulation Factor IX, light chain, ... | | 著者 | Alexander, R.S, Smallwood, A.M, Smallheer, J.M, Wang, J, Wang, S, Nakajima, S, Rossi, K.A, Barbera, F, Burdick, D, Luettgen, J.M. | | 登録日 | 2004-08-13 | | 公開日 | 2005-08-16 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | SAR and factor IXa crystal structure of a dual inhibitor of factors IXa and Xa
Bioorg.Med.Chem.Lett., 14, 2004
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1YDI
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