PDB: 13258 件ウェブページステータス検索Chemie searchBIRD

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7O1F	PCNA from Chaetomium thermophilum in complex with PolD4 PIP peptide 分子名称: Peptide fragment from PolD4, Proliferating cell nuclear antigen, SODIUM ION 著者 Alphey, M.A, MacNeill, S, Yang, D. 登録日 2021-03-29 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix. Febs J., 290, 2023
7O1E	Crystal structure of PCNA from Chaetomium thermophilum 分子名称: Proliferating cell nuclear antigen 著者 Alphey, M.A, MacNeill, S, Yang, D. 登録日 2021-03-29 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Non-canonical binding of the Chaetomium thermophilum PolD4 N-terminal PIP motif to PCNA involves Q-pocket and compact 2-fork plug interactions but no 3 10 helix. Febs J., 290, 2023
7AW9	CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA 分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2020-11-06 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
7AW7	CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA 分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2020-11-06 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
2JK1	Crystal structure of the wild-type HupR receiver domain 分子名称: HYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN HUPR1, MAGNESIUM ION 著者 Davies, K.M, Lowe, E.D, Venien-Bryan, C, Johnson, L.N. 登録日 2008-05-26 公開日 2008-11-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Hupr Receiver Domain Crystal Structure in its Nonphospho and Inhibitory Phospho States. J.Mol.Biol., 385, 2009
6ZU8	Crystal structure of human Brachyury G177D variant in complex with Afatinib 分子名称: Brachyury protein, N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydrofuran-3-yloxy]quinazolin-6-yl}-4-(dimethylamino)butanamide, ZINC ION 著者 Newman, J.A, Gavard, A.E, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. 登録日 2020-07-21 公開日 2020-08-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of human Brachyury G177D variant in complex with Afatinib To Be Published
7BA7	Cys-42-tethered stabilizer 9 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-[3,5-bis(chloranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA5	Cys-42-tethered stabilizer 7 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-fluoranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA9	Cys-42-tethered stabilizer 11 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-methyl-2-(4-methylphenoxy)-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BAA	Cys-42-tethered stabilizer 12 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-bromanyl-3-methoxy-phenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA8	Cys-42-tethered stabilizer 10 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-methyl-2-phenoxy-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9T	Cys-45-tethered stabilizer 5 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-chlorophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)ethanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-14 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA6	Cys-42-tethered stabilizer 8 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-[3,5-bis(fluoranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BAB	Cys-42-tethered stabilizer 13 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-[2-chloranyl-4-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9M	Cys-45-tethered stabilizer 3 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(2-sulfanylethyl)benzamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-14 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9R	Cys-45-tethered stabilizer 4 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)benzamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-14 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA3	Cys-42-tethered stabilizer 6 of 14-3-3(sigma)/ERa PPI 分子名称: 14-3-3 protein sigma, 2-(4-bromanylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... 著者 Sijbesma, E, Ottmann, C. 登録日 2020-12-15 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BMC	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
7BM9	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
1Y0V	Crystal structure of anthrax edema factor (EF) in complex with calmodulin and pyrophosphate 分子名称: CALCIUM ION, Calmodulin, Calmodulin-sensitive adenylate cyclase, ... 著者 Shen, Y, Zhukovskaya, N.L, Guo, Q, Florian, J, Tang, W.-J. 登録日 2004-11-16 公開日 2005-05-03 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Calcium-independent calmodulin binding and two-metal-ion catalytic mechanism of anthrax edema factor Embo J., 24, 2005
2KKW	SLAS-micelle bound alpha-synuclein 分子名称: Alpha-synuclein 著者 Rao, J, Jao, C.C, Hegde, B, Langen, R, Ulmer, T.S. 登録日 2009-06-29 公開日 2010-06-16 最終更新日 2024-05-01 実験手法 EPR, SOLUTION NMR 主引用文献 A combinatorial NMR and EPR approach for evaluating the structural ensemble of partially folded proteins. J.Am.Chem.Soc., 132, 2010
1PIS	SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. 登録日 1994-12-22 公開日 1995-06-03 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of porcine pancreatic phospholipase A2. EMBO J., 14, 1995
1PIR	SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 分子名称: CALCIUM ION, PHOSPHOLIPASE A2 著者 Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. 登録日 1994-12-22 公開日 1995-06-03 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of porcine pancreatic phospholipase A2. EMBO J., 14, 1995
2N0A	Atomic-resolution structure of alpha-synuclein fibrils 分子名称: Alpha-synuclein 著者 Tuttle, M.D, Comellas, G, Nieuwkoop, A.J, Covell, D.J, Berthold, D.A, Kloepper, K.D, Courtney, J.M, Kim, J.K, Schwieters, C.D, Lee, V.M, George, J.M, Rienstra, C.M. 登録日 2015-03-04 公開日 2016-03-23 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein. Nat.Struct.Mol.Biol., 23, 2016
2P6B	Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide 分子名称: CALCIUM ION, Calcineurin subunit B isoform 1, Calmodulin-dependent calcineurin A subunit alpha isoform, ... 著者 Li, H, Zhang, L, Rao, A, Harrison, S.C, Hogan, P.G. 登録日 2007-03-16 公開日 2007-06-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction J.Mol.Biol., 369, 2007

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