8ERM
 
 | | Crystal structure of FliC D2/D3 domains from Pseudomonas aeruginosa PAO1 | | 分子名称: | B-type flagellin, GLYCEROL, SULFATE ION | | 著者 | Nedeljkovic, M, Bonsor, D.A, Postel, S, Sundberg, E.J. | | 登録日 | 2022-10-12 | | 公開日 | 2023-05-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.475 Å) | | 主引用文献 | An unbroken network of interactions connecting flagellin domains is required for motility in viscous environments.
Plos Pathog., 19, 2023
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7RQ6
 | | Cryo-EM structure of SARS-CoV-2 spike in complex with non-neutralizing NTD-directed CV3-13 Fab isolated from convalescent individual | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CV3-13 Fab heavy chain, ... | | 著者 | Chen, Y, Pozharski, E, Tolbert, W.D, Pazgier, M. | | 登録日 | 2021-08-05 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-08-09 | | 実験手法 | ELECTRON MICROSCOPY (4.18 Å) | | 主引用文献 | A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.
Cell Rep, 38, 2022
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8F0G
 | | Structure of SARS-CoV-2 Omicron BA.1 spike in complex with antibody Fab 1C3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 1C3 Fab Heavy Chain, ... | | 著者 | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | | 登録日 | 2022-11-02 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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8F0H
 | | Structure of SARS-CoV-2 spike with antibody Fabs 2A10 and 1H2 (Local refinement of the RBD and Fabs 1H2 and 2A10) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 1H2 heavy chain, Antibody Fab 1H2 light chain, ... | | 著者 | Yu, X, Zyla, D, Hastie, K.M, Saphire, E.O. | | 登録日 | 2022-11-02 | | 公開日 | 2023-05-03 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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7RM6
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1H8G
 | | C-terminal domain of the major autolysin (C-LytA) from Streptococcus pneumoniae | | 分子名称: | CHOLINE ION, MAJOR AUTOLYSIN | | 著者 | Fernandez-Tornero, C, Garcia, E, Lopez, R, Gimenez-Gallego, G, Romero, A. | | 登録日 | 2001-02-06 | | 公開日 | 2002-01-31 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Novel Solenoid Fold in the Cell Wall Anchoring Domain of the Pneumococcal Virulence Factor Lyta
Nat.Struct.Biol., 8, 2001
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7OZS
 | | Structure of the hexameric 5S RNP from C. thermophilum | | 分子名称: | 5S rRNA, 60S ribosomal protein l5-like protein, Putative ribosomal protein, ... | | 著者 | Castillo, N, Thoms, M, Flemming, D, Hammaren, H.M, Buschauer, R, Ameismeier, M, Bassler, J, Beck, M, Beckmann, R, Hurt, E. | | 登録日 | 2021-06-28 | | 公開日 | 2022-10-12 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of nascent 5S RNPs at the crossroad between ribosome assembly and MDM2-p53 pathways.
Nat.Struct.Mol.Biol., 2023
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8J9R
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6NB7
 | | SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S230 heavy chain, ... | | 著者 | Walls, A.C, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, S, Quispe, J, Cameroni, E, Gopal, R, Mian, D, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | | 登録日 | 2018-12-06 | | 公開日 | 2019-02-06 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
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6QK4
 | | Lytic transglycosylase, LtgG, of Burkholderia pseudomallei. | | 分子名称: | Membrane-bound lytic murein transglycosylase A | | 著者 | Jenkins, C.H, Wallis, R, Allcock, N, Barnes, K.B, Richards, M.I, Auty, J.M, Galyov, E.E, Harding, S.V, Mukamolova, G.V. | | 登録日 | 2019-01-28 | | 公開日 | 2019-08-14 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | The lytic transglycosylase, LtgG, controls cell morphology and virulence in Burkholderia pseudomallei.
Sci Rep, 9, 2019
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5EF0
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 16.7 MGy | | 分子名称: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | 著者 | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | 登録日 | 2015-10-23 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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6FPW
 | | Structure of fully reduced Hydrogenase (Hyd-1) | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, FE3-S4 CLUSTER, ... | | 著者 | Carr, S.B, Armstrong, F.A, Evans, R.M. | | 登録日 | 2018-02-12 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Mechanistic Exploitation of a Self-Repairing, Blocked Proton Transfer Pathway in an O2-Tolerant [NiFe]-Hydrogenase.
J. Am. Chem. Soc., 140, 2018
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6G95
 | | Crystal structure of Ebolavirus glycoprotein in complex with thioridazine | | 分子名称: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | | 著者 | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | | 登録日 | 2018-04-10 | | 公開日 | 2018-05-23 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
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6NES
 | | FAD-dependent monooxygenase TropB from T. stipitatus | | 分子名称: | CHLORIDE ION, FAD-dependent monooxygenase tropB, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Rodriguez Benitez, A, Tweedy, S.E, Baker Dockrey, S.A, Lukowski, A.L, Wymore, T, Khare, D, Brooks, C.L, Palfey, B.A, Smith, J.L, Narayan, A.R.H. | | 登録日 | 2018-12-18 | | 公開日 | 2019-08-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.
Acs Catalysis, 9, 2019
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8E1G
 | | SARS-CoV-2 RBD in complex with Omicron-neutralizing antibody 2A10 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A10 Fab, heavy chain, ... | | 著者 | Wasserman, H, Hastie, K.M, Buck, T.K, Saphire, E.O. | | 登録日 | 2022-08-10 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Potent Omicron-neutralizing antibodies isolated from a patient vaccinated 6 months before Omicron emergence.
Cell Rep, 42, 2023
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8EF7
 | | CryoEM of the soluble OPA1 dimer from the apo helical assembly on a lipid membrane | | 分子名称: | Dynamin-like 120 kDa protein, form S1 | | 著者 | Nyenhuis, S.B, Wu, X, Stanton, A.E, Strub, M.P, Yim, Y.I, Canagarajah, B, Hinshaw, J.E. | | 登録日 | 2022-09-08 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (9.68 Å) | | 主引用文献 | OPA1 helical structures give perspective to mitochondrial dysfunction.
Nature, 620, 2023
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6TAO
 | | The cytotoxin MakE from Vibrio cholerae | | 分子名称: | NICKEL (II) ION, Non-hemolytic enterotoxin lytic component L1, SULFATE ION | | 著者 | Persson, K, Nagampalli, R, Heidler, T, Wai, S.N. | | 登録日 | 2019-10-30 | | 公開日 | 2020-11-18 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | A tripartite cytolytic toxin formed by Vibrio cholerae proteins with flagellum-facilitated secretion.
Proc.Natl.Acad.Sci.USA, 118, 2021
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5KTO
 | | Crystal structure of Pyrococcus horikoshii quinolinate synthase (NadA) with bound quinolinate and Fe4S4 cluster | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | | 著者 | Fenwick, M.K, Ealick, S.E. | | 登録日 | 2016-07-12 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.442 Å) | | 主引用文献 | Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate.
Biochemistry, 55, 2016
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5EEV
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 3.88 MGy | | 分子名称: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | 著者 | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | 登録日 | 2015-10-23 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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1Y3B
 | | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 E60S mutant | | 分子名称: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | | 著者 | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | | 登録日 | 2004-11-24 | | 公開日 | 2005-05-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
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6GFY
 | | pVHL:EloB:EloC in complex with modified VH032 containing (3R,4S)-3-fluoro-4-hydroxyproline (ligand 14a) | | 分子名称: | (2~{R},3~{R},4~{S})-1-[(2~{S})-2-acetamido-3,3-dimethyl-butanoyl]-3-fluoranyl-~{N}-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Gadd, M.S, Testa, A, Ciulli, A. | | 登録日 | 2018-05-02 | | 公開日 | 2018-07-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | 3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
J. Am. Chem. Soc., 140, 2018
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1Y48
 | | Crystal structure of the complex of subtilisin BPN' with chymotrypsin inhibitor 2 R65A mutant | | 分子名称: | CALCIUM ION, CITRIC ACID, POLYETHYLENE GLYCOL (N=34), ... | | 著者 | Radisky, E.S, Lu, C.J, Kwan, G, Koshland Jr, D.E. | | 登録日 | 2004-11-30 | | 公開日 | 2005-05-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Role of the intramolecular hydrogen bond network in the inhibitory power of chymotrypsin inhibitor 2
Biochemistry, 44, 2005
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5EEX
 | | RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 9.02 MGy | | 分子名称: | (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB | | 著者 | Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B. | | 登録日 | 2015-10-23 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
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8CWP
 | | X-ray crystal structure of NTHi Protein D bound to a putative glycerol moiety | | 分子名称: | GLYCEROL, Glycerophosphoryl diester phosphodiesterase, SODIUM ION | | 著者 | Jones, S.P, Cook, K.H, Holmquist, M.L, Almekinder, L, DeLaney, A, Labbe, N, Perdue, J, Jackson, N, Charles, R, Pichichero, M, Kaur, R, Michel, L, Gleghorn, M.L. | | 登録日 | 2022-05-19 | | 公開日 | 2022-09-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Vaccine target and carrier molecule nontypeable Haemophilus influenzae protein D dimerizes like the close Escherichia coli GlpQ homolog but unlike other known homolog dimers.
Proteins, 91, 2023
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7Q4M
 | | Type II beta-amyloid 42 Filaments from Human Brain | | 分子名称: | Amyloid-beta precursor protein, UNKNOWN ATOM OR ION | | 著者 | Yang, Y, Arseni, D, Zhang, W, Huang, M, Lovestam, S.K.A, Schweighauser, M, Kotecha, A, Murzin, A.G, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Garringer, H.J, Gelpi, E, Newell, K.L, Kovacs, G.G, Vidal, R, Ghetti, B, Falcon, B, Scheres, S.H.W, Goedert, M. | | 登録日 | 2021-11-01 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of amyloid-beta 42 filaments from human brains.
Science, 375, 2022
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