4W9X
| Crystal Structure of BMP-2-inducible kinase in complex with baricitinib | 分子名称: | 1,2-ETHANEDIOL, BMP-2-inducible protein kinase, Baricitinib | 著者 | Sorrell, F.J, Elkins, J.M, Krojer, T, Williams, E, Savitsky, P, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-08-28 | 公開日 | 2014-09-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Family-wide Structural Analysis of Human Numb-Associated Protein Kinases. Structure, 24, 2016
|
|
4WA5
| The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with zanamivir | 分子名称: | CALCIUM ION, Neuraminidase, ZANAMIVIR, ... | 著者 | Yang, H, Villanueva, J.M, Gubareva, L.V, Stevens, J. | 登録日 | 2014-08-28 | 公開日 | 2015-01-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89, 2015
|
|
4WCO
| Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A | 分子名称: | ACETATE ION, C-type lectin domain family 2 member D, SULFATE ION, ... | 著者 | Kita, S, Matsubara, H, Kasai, Y, Tamaoki, T, Okabe, Y, Fukuhara, H, Kamishikiryo, J, Ose, T, Kuroki, K, Maenaka, K. | 登録日 | 2014-09-05 | 公開日 | 2015-06-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Crystal structure of extracellular domain of human lectin-like transcript 1 (LLT1), the ligand for natural killer receptor-P1A Eur.J.Immunol., 45, 2015
|
|
4V0L
| |
4W94
| Crystal structure of cross-linked tetragonal hen egg white lysozyme soaked with 5mM [Ru(CO)3Cl2]2 | 分子名称: | CHLORIDE ION, DIMETHYLFORMAMIDE, Lysozyme C, ... | 著者 | Tabe, H, Fujita, K, Abe, S, Tsujimoto, M, Kuchimaru, T, Kizaka-Kondo, S, Takano, M, Kitagawa, S, Ueno, T. | 登録日 | 2014-08-27 | 公開日 | 2014-12-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Preparation of a Cross-Linked Porous Protein Crystal Containing Ru Carbonyl Complexes as a CO-Releasing Extracellular Scaffold Inorg.Chem., 54, 2015
|
|
4W4W
| JNK2/3 in complex with N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide | 分子名称: | N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide, c-Jun N-terminal kinase 3 | 著者 | Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P. | 登録日 | 2014-08-15 | 公開日 | 2015-02-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles. Sci Rep, 5, 2015
|
|
4W9W
| Crystal Structure of BMP-2-inducible kinase in complex with small molecule AZD-7762 | 分子名称: | 1,2-ETHANEDIOL, 5-(3-fluorophenyl)-N-[(3S)-3-piperidyl]-3-ureido-thiophene-2-carboxamide, BMP-2-inducible protein kinase | 著者 | Sorrell, F.J, Elkins, J.M, Krojer, T, Savitsky, P, Williams, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2014-08-28 | 公開日 | 2014-09-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Family-wide Structural Analysis of Human Numb-Associated Protein Kinases. Structure, 24, 2016
|
|
4W92
| Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, 1,2-ETHANEDIOL, C-di-AMP ribsoswitch, ... | 著者 | Jones, C.P, Ferre-D'Amare, A.R. | 登録日 | 2014-08-26 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.209 Å) | 主引用文献 | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA. Embo J., 33, 2014
|
|
4W9B
| Crystal structure of Gamma-B Crystallin expressed in E. coli based on mRNA variant 1 | 分子名称: | Gamma-crystallin B | 著者 | Kudlinzki, D, Buhr, F, Linhard, V.L, Jha, S, Komar, A.A, Schwalbe, H. | 登録日 | 2014-08-27 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.279 Å) | 主引用文献 | Two synonymous gene variants encode proteins with identical sequence, but different folding conformations. To Be Published
|
|
4WCH
| Structure of Isolated D Chain of Gigant Hemoglobin from Glossoscolex paulistus | 分子名称: | Isolated Chain D of Gigant Hemoglobin from Glossoscolex Paulistus, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Bachega, J.F.R, Maluf, F.V, Pereira, H.M, Brandao-Neto, J, Tabak, M, Garratt, R.C, Horjales, E. | 登録日 | 2014-09-04 | 公開日 | 2015-06-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The structure of the giant haemoglobin from Glossoscolex paulistus. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4WA7
| Crystal Structure of a GDP-bound Q61L Oncogenic Mutant of Human GT- Pase KRas | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Hunter, J.C, Manandhar, A, Gurbani, D, Chen, Z, Westover, K.D. | 登録日 | 2014-08-28 | 公開日 | 2015-06-10 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations. Mol Cancer Res., 13, 2015
|
|
4WAN
| Crystal structure of Msl5 protein in complex with RNA at 1.8 A | 分子名称: | ACETATE ION, Branchpoint-bridging protein, GLYCEROL, ... | 著者 | Jacewicz, A, Smith, P, Chico, L, Schwer, B, Shuman, S. | 登録日 | 2014-08-29 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs. Rna, 21, 2015
|
|
4WAL
| Crystal structure of selenomethionine Msl5 protein in complex with RNA at 2.2 A | 分子名称: | Branchpoint-bridging protein, CHLORIDE ION, GLYCEROL, ... | 著者 | Jacewicz, A, Smith, P, Chico, L, Schwer, B, Shuman, S. | 登録日 | 2014-08-29 | 公開日 | 2014-12-17 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for recognition of intron branchpoint RNA by yeast Msl5 and selective effects of interfacial mutations on splicing of yeast pre-mRNAs. Rna, 21, 2015
|
|
4WB5
| Crystal structure of human cAMP-dependent protein kinase A (catalytic alpha subunit) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PKI (5-24), ... | 著者 | Cheung, J, Ginter, C, Cassidy, M, Franklin, M.C, Rudolph, M.J, Hendrickson, W.A. | 登録日 | 2014-09-02 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | Structural insights into mis-regulation of protein kinase A in human tumors. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
4WA4
| The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase, ... | 著者 | Yang, H, Villanueva, J.M, Gubareva, L.V, Stevens, J. | 登録日 | 2014-08-28 | 公開日 | 2015-01-14 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Functional Analysis of Surface Proteins from an A(H3N8) Influenza Virus Isolated from New England Harbor Seals. J.Virol., 89, 2015
|
|
4WEG
| influenza virus neuraminidase N9 in complex 2,3-difluorosialic acid | 分子名称: | (2R,3R,4R,5R,6R)-5-acetamido-2,3-difluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylic acid, (3R,4R,5R,6R)-5-(acetylamino)-3-fluoro-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4,5,6-tetrahydropyranium-2-carboxylate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Streltsov, V.A, Pilling, P, Barrett, S, McKimm-Breschkin, J. | 登録日 | 2014-09-10 | 公開日 | 2015-09-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Catalytic mechanism and novel receptor binding sites of human parainfluenza virus type 3 hemagglutinin-neuraminidase (hPIV3 HN) Antiviral Res., 123, 2015
|
|
4UQT
| RRM-peptide structure in RES complex | 分子名称: | PRE-MRNA-SPLICING FACTOR CWC26, U2 SNRNP COMPONENT IST3 | 著者 | Tripsianes, K, Friberg, A, Barrandon, C, Seraphin, B, Sattler, M. | 登録日 | 2014-06-25 | 公開日 | 2014-09-03 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | A Novel Protein-Protein Interaction in the Res (Retention and Splicing) Complex. J.Biol.Chem., 289, 2014
|
|
4V2L
| |
4UWN
| Lysozyme soaked with a ruthenium based CORM with a methione oxide ligand (complex 6b) | 分子名称: | CARBON MONOXIDE, CHLORIDE ION, GLYCEROL, ... | 著者 | Santos, M.F.A, Mukhopadhyay, A, Romao, M.J, Romao, C.C, Santos-Silva, T. | 登録日 | 2014-08-13 | 公開日 | 2014-12-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | A Contribution to the Rational Design of Ru(Co)3Cl2L Complexes for in Vivo Delivery of Co. Dalton Trans, 44, 2015
|
|
4V2M
| |
4UXM
| Crystal Structure of Struthiocalcin-1, a different crystal form. | 分子名称: | (4-CARBOXYPHENYL)(CHLORO)MERCURY, STRUTHIOCALCIN-1 | 著者 | Ruiz-Arellano, R.R, Moreno, A, Romero, A. | 登録日 | 2014-08-26 | 公開日 | 2015-04-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal Structure of Struthiocalcin-1, an Intramineral Protein from Struthio Camelus Eggshell, in Two Different Crystal Forms. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4V2N
| |
4UUT
| |
4UZD
| SAR156497 an exquisitely selective inhibitor of Aurora kinases | 分子名称: | AURORA KINASE A, ethyl (9S)-9-[3-(1H-benzimidazol-2-yloxy)phenyl]-8-oxo-4,5,6,7,8,9-hexahydro-2H-pyrrolo[3,4-b]quinoline-3-carboxylate | 著者 | Pouzieux, S, Delarbre, L, Crenne, J.Y. | 登録日 | 2014-09-05 | 公開日 | 2014-11-19 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Sar156497 an Exquisitely Selective Inhibitor of Aurora Kinases. J.Med.Chem., 58, 2015
|
|
4V0K
| |