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1ATK
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH THE COVALENT INHIBITOR E-64
分子名称: CATHEPSIN K, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE
著者Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日1996-12-19
公開日1998-02-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human osteoclast cathepsin K complex with E-64.
Nat.Struct.Biol., 4, 1997
1ATL
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Structural interaction of natural and synthetic inhibitors with the VENOM METALLOPROTEINASE, ATROLYSIN C (FORM-D)
分子名称: CALCIUM ION, O-methyl-N-[(2S)-4-methyl-2-(sulfanylmethyl)pentanoyl]-L-tyrosine, Snake venom metalloproteinase atrolysin-D, ...
著者Zhang, D, Botos, I, Gomis-Rueth, F.-X, Doll, R, Blood, C, Njoroge, F.G, Fox, J.W, Bode, W, Meyer, E.F.
登録日1995-05-26
公開日1995-10-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d).
Proc.Natl.Acad.Sci.USA, 91, 1994
1ATN
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Atomic structure of the actin:DNASE I complex
分子名称: ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Kabsch, W, Mannherz, H.G, Suck, D, Pai, E, Holmes, K.C.
登録日1991-03-08
公開日1992-07-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure of the actin:DNase I complex.
Nature, 347, 1990
1ATO
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THE STRUCTURE OF THE ISOLATED, CENTRAL HAIRPIN OF THE HDV ANTIGENOMIC RIBOZYME, NMR, 10 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*CP*AP*CP*CP*UP*CP*CP*UP*CP*GP*CP*GP*GP*UP*GP*CP*C)-3')
著者Kolk, M.H, Heus, H.A, Hilbers, C.W.
登録日1997-08-14
公開日1997-11-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The structure of the isolated, central hairpin of the HDV antigenomic ribozyme: novel structural features and similarity of the loop in the ribozyme and free in solution.
EMBO J., 16, 1997
1ATP
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2.2 angstrom refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MNATP and a peptide inhibitor
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PEPTIDE INHIBITOR PKI(5-24), ...
著者Zheng, J, Trafny, E.A, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Teneyck, L.F, Sowadski, J.M.
登録日1993-01-08
公開日1993-04-15
最終更新日2019-08-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.
Acta Crystallogr.,Sect.D, 49, 1993
1ATR
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THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS
分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT-SHOCK COGNATE 70 KD PROTEIN, MAGNESIUM ION, ...
著者O'Brien, M.C, Mckay, D.B.
登録日1993-08-09
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Threonine 204 of the chaperone protein Hsc70 influences the structure of the active site, but is not essential for ATP hydrolysis.
J.Biol.Chem., 268, 1993
1ATS
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THREONINE 204 OF THE CHAPERONE PROTEIN HSC70 INFLUENCES THE STRUCTURE OF THE ACTIVE SITE BUT IS NOT ESSENTIAL FOR ATP HYDROLYSIS
分子名称: ADENOSINE-5'-DIPHOSPHATE, HEAT-SHOCK COGNATE 70 KD PROTEIN, MAGNESIUM ION
著者O'Brien, M.C, Mckay, D.B.
登録日1993-08-09
公開日1993-10-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献Threonine 204 of the chaperone protein Hsc70 influences the structure of the active site, but is not essential for ATP hydrolysis.
J.Biol.Chem., 268, 1993
1ATT
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CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION
分子名称: ANTITHROMBIN III
著者Mourey, L, Samama, J.P, Delarue, M, Moras, D.
登録日1993-03-29
公開日1994-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution.
J.Mol.Biol., 232, 1993
1ATU
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UNCLEAVED ALPHA-1-ANTITRYPSIN
分子名称: ALPHA-1-ANTITRYPSIN
著者Ryu, S.-E, Choi, H.-J.
登録日1997-05-11
公開日1997-08-20
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A.
Structure, 4, 1996
1ATV
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HAIRPIN WITH AGAA TETRALOOP, NMR, 4 STRUCTURES
分子名称: RNA (5'-R(*GP*GP*GP*AP*CP*CP*AP*GP*AP*AP*GP*GP*UP*CP*CP*CP*G)-3')
著者Kang, H.
登録日1997-08-14
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Primary Sequence at the Junction of Stem and Loop in RNA Hairpins Affects the Three-Dimensional Conformation in Solution
To be Published
1ATW
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HAIRPIN WITH AGAU TETRALOOP, NMR, 3 STRUCTURES
分子名称: RNA (5'-R(*GP*CP*UP*CP*CP*AP*GP*AP*UP*GP*GP*AP*GP*CP*G)-3')
著者Kang, H.
登録日1997-08-14
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Primary Sequence at the Junction of Stem and Loop in RNA Hairpins Affects the Three-Dimensional Conformation in Solution
To be Published
1ATX
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BU of 1atx by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE NEUROTOXIN ATX IA FROM ANEMONIA SULCATA IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
分子名称: ATX IA
著者Billeter, M, Widmer, H, Wuthrich, K.
登録日1990-05-14
公開日1991-04-15
最終更新日2024-10-16
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopy.
Proteins, 6, 1989
1ATY
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DETERMINATION OF LOCAL PROTEIN STRUCTURE BY SPIN LABEL DIFFERENCE 2D NMR: THE REGION NEIGHBORING ASP61 OF SUBUNIT C OF THE F1FO ATP SYNTHASE
分子名称: F1F0 ATP SYNTHASE (SUBUNIT C)
著者Girvin, M.E, Fillingame, R.H.
登録日1994-10-05
公開日1994-12-20
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Determination of local protein structure by spin label difference 2D NMR: the region neighboring Asp61 of subunit c of the F1F0 ATP synthase.
Biochemistry, 34, 1995
1ATZ
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HUMAN VON WILLEBRAND FACTOR A3 DOMAIN
分子名称: VON WILLEBRAND FACTOR
著者Huizinga, E.G, Gros, P.
登録日1997-08-15
公開日1998-02-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of the A3 domain of human von Willebrand factor: implications for collagen binding.
Structure, 5, 1997
1AU0
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT SYMMETRIC DIACYLAMINOMETHYL KETONE INHIBITOR
分子名称: 1,3-BIS[[N-[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL]AMINO]-2-PROPANONE, CATHEPSIN K
著者Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日1997-09-09
公開日1998-10-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Design of Potent and Selective Cathepsin K Inhibitors
J.Am.Chem.Soc., 119, 1997
1AU1
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HUMAN INTERFERON-BETA CRYSTAL STRUCTURE
分子名称: INTERFERON-BETA, ZINC ION, alpha-D-quinovopyranose-(1-6)-beta-D-glucopyranose, ...
著者Karpusas, M, Nolte, M, Lipscomb, W.
登録日1997-09-09
公開日1998-06-17
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The crystal structure of human interferon beta at 2.2-A resolution.
Proc.Natl.Acad.Sci.USA, 94, 1997
1AU2
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PROPANONE INHIBITOR
分子名称: 1-[[(4-PHENOXYPHENYL)SULFONYL]AMINO]-3-[[N/N-(4-PYRIDINYLCARBONYL)-L-LEUCYL]AMINO]-2-PROPANOL, CATHEPSIN K
著者Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日1997-09-10
公開日1998-10-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and Design of Potent and Selective Cathepsin K Inhibitors
J.Am.Chem.Soc., 119, 1997
1AU3
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PYRROLIDINONE INHIBITOR
分子名称: 1-[N[(PHENYLMETHOXY)CARBONYL]-L-LEUCYL-4-[[N/N-[(PHENYLMETHOXY)CARBONYL]-/NL-LEUCYL]AMINO]-3-PYRROLIDINONE/N, CATHEPSIN K
著者Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日1997-09-10
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K.
J.Med.Chem., 41, 1998
1AU4
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CRYSTAL STRUCTURE OF THE CYSTEINE PROTEASE HUMAN CATHEPSIN K IN COMPLEX WITH A COVALENT PYRROLIDINONE INHIBITOR
分子名称: 4-[[N-[(PHENYLMETHOXY)CARBONYL]-/NL/N-LEUCYL]AMINO]-1[(2S)-2-[[[4-(PYRIDINYLMETHOXY)CARBONYL]AMINO]-4-METHYLPENT/NYL]-3-PYRROLIDINONE/N, CATHEPSIN K
著者Zhao, B, Smith, W.W, Janson, C.A, Abdel-Meguid, S.S.
登録日1997-09-10
公開日1998-10-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Conformationally constrained 1,3-diamino ketones: a series of potent inhibitors of the cysteine protease cathepsin K.
J.Med.Chem., 41, 1998
1AU5
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SOLUTION STRUCTURE OF INTRASTRAND CISPLATIN-CROSSLINKED DNA OCTAMER D(CCTG*G*TCC):D(GGACCAGG), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: Cisplatin, DNA (5'-D(*CP*CP*TP*GP*GP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*CP*CP*AP*GP*G)-3')
著者Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Wang, A.H.-J.
登録日1997-09-11
公開日1998-02-25
最終更新日2024-04-10
実験手法SOLUTION NMR
主引用文献Structure and isomerization of an intrastrand cisplatin-cross-linked octamer DNA duplex by NMR analysis.
Biochemistry, 34, 1995
1AU6
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SOLUTION STRUCTURE OF DNA D(CATGCATG) INTERSTRAND-CROSSLINKED BY BISPLATIN COMPOUND (1,1/T,T), NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: BIS(TRANS-PLATINUM ETHYLENEDIAMINE DIAMINE CHLORO)COMPLEX, DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3')
著者Yang, D, Van Boom, S.S.G.E, Reedijk, J, Van Boom, J.H, Farrell, N, Wang, A.H.-J.
登録日1997-09-11
公開日1998-02-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A novel DNA structure induced by the anticancer bisplatinum compound crosslinked to a GpC site in DNA.
Nat.Struct.Biol., 2, 1995
1AU7
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PIT-1 MUTANT/DNA COMPLEX
分子名称: CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1
著者Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K.
登録日1997-09-12
公開日1998-01-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility.
Genes Dev., 11, 1997
1AU8
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HUMAN CATHEPSIN G
分子名称: CATHEPSIN G, N-(3-carboxypropanoyl)-L-valyl-N-[(1R)-5-amino-1-phosphonopentyl]-L-prolinamide
著者Medrano, F.J, Bode, W, Banbula, A, Potempa, J.
登録日1997-09-12
公開日1998-10-14
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献HUMAN CATHEPSIN G
to be published
1AU9
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SUBTILISIN BPN' MUTANT 8324 IN CITRATE
分子名称: CALCIUM ION, ISOPROPYL ALCOHOL, SUBTILISIN BPN', ...
著者Whitlow, M, Howard, A.J, Wood, J.F.
登録日1997-09-12
公開日1997-12-31
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding.
Biochemistry, 28, 1989
1AUA
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PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P FROM SACCHAROMYCES CEREVISIAE
分子名称: PHOSPHATIDYLINOSITOL TRANSFER PROTEIN SEC14P, octyl beta-D-glucopyranoside
著者Sha, B, Phillips, S.E, Bankaitis, V.A, Luo, M.
登録日1997-08-20
公開日1997-12-24
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein.
Nature, 391, 1998

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