PDB: 56562 件ウェブページステータス検索Chemie searchBIRD

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5LD8	GSK3011724A cocrystallised with Mycobacterium tuberculosis H37Rv KasA 分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 1, SODIUM ION, TETRAETHYLENE GLYCOL, ... 著者 Chung, C.W, Neu, M. 登録日 2016-06-23 公開日 2016-09-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Identification of KasA as the cellular target of an anti-tubercular scaffold. Nat Commun, 7, 2016
8JAV	Structure of CRL2APPBP2 bound with the C-degron of MRPL28 (tetramer) 分子名称: Amyloid protein-binding protein 2, Cullin-2, E3 ubiquitin-protein ligase RBX1, ... 著者 Zhao, S, Zhang, K, Xu, C. 登録日 2023-05-07 公開日 2023-10-18 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (3.44 Å) 主引用文献 Molecular basis for C-degron recognition by CRL2 APPBP2 ubiquitin ligase. Proc.Natl.Acad.Sci.USA, 120, 2023
6ZL4	the structure of glutamate transporter homologue GltTk in complex with the photo switchable compound (cis) 分子名称: (2~{S},3~{S})-2-azanyl-3-[[4-[2-(4-methoxyphenyl)hydrazinyl]phenyl]methoxy]butanedioic acid, DECYL-BETA-D-MALTOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, ... 著者 Arkhipova, V, Slotboom, D.J, Guskov, A. 登録日 2020-06-30 公開日 2021-01-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural Aspects of Photopharmacology: Insight into the Binding of Photoswitchable and Photocaged Inhibitors to the Glutamate Transporter Homologue. J.Am.Chem.Soc., 143, 2021
5LZ7	Fragment-based inhibitors of Lipoprotein associated Phospholipase A2 分子名称: 2-fluoranyl-5-[2-[(4~{R})-4-methyl-2-oxidanylidene-4-phenyl-pyrrolidin-1-yl]ethoxy]benzenecarbonitrile, CHLORIDE ION, Platelet-activating factor acetylhydrolase 著者 Woolford, A, Day, P. 登録日 2016-09-29 公開日 2016-12-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Fragment-Based Approach to the Development of an Orally Bioavailable Lactam Inhibitor of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2). J. Med. Chem., 59, 2016
6LJN	Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P15 分子名称: 7-AMINO-4-METHYL-CHROMEN-2-ONE, ACE-HIS-PHE-SER-SLL, NAD-dependent protein deacylase sirtuin-5, ... 著者 Chen, Q, Yu, Y. 登録日 2019-12-17 公開日 2020-10-28 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery. Eur.J.Med.Chem., 192, 2020
7TTC	BamABCDE bound to substrate EspP 分子名称: 2,3-dideoxy-6-O-[2-deoxy-4-O-phosphono-2-(tetradecanoylamino)-alpha-L-gulopyranosyl]-1-O-phosphono-beta-D-threo-hexopyranose, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... 著者 Doyle, M.T, Jimah, J.R, Dowdy, T, Ohlemacher, S.I, Larion, M, Hinshaw, J.E, Bernstein, H.D. 登録日 2022-02-01 公開日 2022-03-30 最終更新日 2022-04-13 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell, 185, 2022
6S1I	Crystal Structure of DYRK1A with small molecule inhibitor 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 1A, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Sorrell, F.J, Henderson, S.H, Redondo, C, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Elkins, J.M. 登録日 2019-06-18 公開日 2019-06-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 Mining Public Domain Data to Develop Selective DYRK1A Inhibitors. Acs Med.Chem.Lett., 11, 2020
5JAN	Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening 分子名称: 1,3-dimethyl-6-(2-methylpropoxy)pyrimidine-2,4(1H,3H)-dione, CALCIUM ION, CHLORIDE ION, ... 著者 Day, P.J. 登録日 2016-04-12 公開日 2016-05-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. J.Med.Chem., 59, 2016
6L0J	Crystal structure of Dihydroorotase in complex with malate at pH7.5 from Saccharomyces cerevisiae 分子名称: (2S)-2-hydroxybutanedioic acid, Dihydroorotase, ZINC ION 著者 Guan, H.H, Huang, Y.H, Huang, C.Y, Chen, C.J. 登録日 2019-09-26 公開日 2020-12-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.933 Å) 主引用文献 Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism Molecules, 2021
8AUC	Structure of peptidoglycan hydrolase Cg1735 from Corynebacterium glutamicum, trigonal crystal form 分子名称: Cell wall-associated hydrolases (Invasion-associated proteins), TETRACHLOROPLATINATE(II) 著者 Gaday, Q, Wehenkel, A.M, Alzari, P.M, Legrand, P. 登録日 2022-08-25 公開日 2023-01-18 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales. Proc.Natl.Acad.Sci.USA, 119, 2022
6KXK	BON1 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Wang, Q.C, Jiang, M.Q, Isupov, M.N, Sun, L.F, Wu, Y.K. 登録日 2019-09-12 公開日 2020-09-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of an Arabidopsis Copine providing insights into this protein family To be published
5J4O	Structure of human erythrocytic Spectrin alpha chain repeats 16-17 分子名称: 1,2-ETHANEDIOL, Spectrin alpha chain, erythrocytic 1, ... 著者 Cutts, E.E, Vakonakis, I. 登録日 2016-04-01 公開日 2017-04-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Interactions of Plasmodium falciparum KAHRP and PfEMP1 with the host cytoskeleton suggest a model for cytoadherent protrusions on the infected erythrocyte surface To Be Published
8IWW	hSPCA1 in the CaE1P-ADP state 分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... 著者 Liu, Z.M, Wu, M.Q, Wu, C. 登録日 2023-03-31 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.71 Å) 主引用文献 Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
8IWU	hSPCA1 in the E2~P state 分子名称: Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, TETRAFLUOROALUMINATE ION 著者 Liu, Z.M, Wu, M.Q, Wu, C. 登録日 2023-03-31 公開日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 Structure and transport mechanism of the human calcium pump SPCA1. Cell Res., 33, 2023
6HXA	AntI from P. luminescens catalyses terminal polyketide shortening in the biosynthesis of anthraquinones 分子名称: AntI, TETRAETHYLENE GLYCOL, TRIETHYLENE GLYCOL 著者 Zhou, Q, Braeuer, A, Grammbitter, G, Schmalhofer, M, Saura, P, Adihou, H, Kaila, V.R.I, Groll, M, Bode, H. 登録日 2018-10-16 公開日 2019-08-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Molecular mechanism of polyketide shortening in anthraquinone biosynthesis ofPhotorhabdus luminescens. Chem Sci, 10, 2019
5M6Q	Crystal Structure of Kutzneria albida transglutaminase 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, TETRAETHYLENE GLYCOL, ... 著者 Steffen, W, Benz, J, Rudolph, M.G. 登録日 2016-10-25 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Discovery of a microbial transglutaminase enabling highly site-specific labeling of proteins. J. Biol. Chem., 292, 2017
5M70	Crystal Structure of human RhoGAP mutated in its arginin finger (R85A) in complex with RhoA.GDP.AlF4- human 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase-activating protein 1, ... 著者 Pellegrini, E, Bowler, M.W. 登録日 2016-10-26 公開日 2017-05-17 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Assessing the Influence of Mutation on GTPase Transition States by Using X-ray Crystallography, (19) F NMR, and DFT Approaches. Angew. Chem. Int. Ed. Engl., 56, 2017
8PWS	Dye-decolourising peroxidase DtpB (56 kGy) 分子名称: MAGNESIUM ION, OXYGEN ATOM, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Lucic, M, Worrall, J.A.R, Hough, M.A, Owen, R.L, Strange, R.W. 登録日 2023-07-21 公開日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Dye-decolourising peroxidase DtpB (56 kGy) To Be Published
5M8X	PCE reductive dehalogenase from S. multivorans in complex with 2,4,5-trichlorophenol 分子名称: 2,4,5-trichlorophenol, BENZAMIDINE, GLYCEROL, ... 著者 Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. 登録日 2016-10-30 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.869 Å) 主引用文献 Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
5MAA	PCE reductive dehalogenase from S. multivorans in complex with 3-bromophenol 分子名称: 3-bromophenol, 5-Methoxybenzimidazolyl-norcobamide, BENZAMIDINE, ... 著者 Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. 登録日 2016-11-03 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.686 Å) 主引用文献 Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
8PNO	The MgF3(H2O) transition state analog complex of E. coli YihX 分子名称: 1,2-ETHANEDIOL, Alpha-D-glucose 1-phosphate phosphatase YihX, CALCIUM ION, ... 著者 Baumann, P, Zappala, D, Jin, Y. 登録日 2023-06-30 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The MgF3(H2O)- transition state analog complex of E. coli YihX To Be Published
8AWZ	Crystal structure of Trametes versicolor glutathione transferase Omega 3S in complex with dinitrosyl glutathionyl iron complex (DNGIC) 分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... 著者 Schwartz, M, Didierjean, C. 登録日 2022-08-30 公開日 2023-03-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.549 Å) 主引用文献 Structural insights into the interactions of glutathione transferases with a nitric oxide carrier and sodium nitroprusside. Biochem.Biophys.Res.Commun., 649, 2023
5M8U	PCE reductive dehalogenase from S. multivorans in complex with 4-bromophenol 分子名称: 4-BROMOPHENOL, BENZAMIDINE, GLYCEROL, ... 著者 Kunze, C, Bommer, M, Hagen, W.R, Uksa, M, Dobbek, H, Schubert, T, Diekert, G. 登録日 2016-10-30 公開日 2017-07-12 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Cobamide-mediated enzymatic reductive dehalogenation via long-range electron transfer. Nat Commun, 8, 2017
8AUM	OPR3 Y190F variant in complex with ethyl (Z)-2-(hydroxyimino)-3-oxopentanoate 分子名称: 12-oxophytodienoate reductase 3, DI(HYDROXYETHYL)ETHER, FLAVIN MONONUCLEOTIDE, ... 著者 Polidori, N, Gruber, K. 登録日 2022-08-25 公開日 2023-03-01 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines. Acs Catalysis, 13, 2023
5JE2	Crystal structure of Burkholderia glumae ToxA Y7F mutant with bound S-adenosylhomocysteine (SAH) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, Methyl transferase, ... 著者 Fenwick, M.K, Philmus, B, Begley, T.P, Ealick, S.E. 登録日 2016-04-17 公開日 2016-05-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.519 Å) 主引用文献 Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis. Biochemistry, 55, 2016

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