8G60
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![BU of 8g60 by Molmil](/molmil-images/mine/8g60) | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8FON
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![BU of 8fon by Molmil](/molmil-images/mine/8fon) | Crystal structure of tRNA^Lys(SUU) bound to AUA codon in the ribosomal P site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | 登録日 | 2023-01-02 | 公開日 | 2023-03-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | 主引用文献 | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches. J.Biol.Chem., 299, 2023
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8FIZ
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![BU of 8fiz by Molmil](/molmil-images/mine/8fiz) | Cryo-EM structure of E. coli 70S Ribosome containing mRNA and tRNA (in the transcription-translation complex) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Florez Ariza, A, Wee, L, Tong, A, Canari, C, Grob, P, Nogales, E, Bustamante, C. | 登録日 | 2022-12-18 | 公開日 | 2023-03-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A trailing ribosome speeds up RNA polymerase at the expense of transcript fidelity via force and allostery. Cell, 186, 2023
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8FOM
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![BU of 8fom by Molmil](/molmil-images/mine/8fom) | Crystal structure of tRNA^Lys(SUU) bound to UAA codon in the ribosomal P site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Nguyen, H.A, Hoffer, E.D, Maehigashi, T, Fagan, C.E, Dunham, C.M. | 登録日 | 2023-01-02 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-26 | 実験手法 | X-RAY DIFFRACTION (3.58 Å) | 主引用文献 | Structural basis for reduced ribosomal A-site fidelity in response to P-site codon-anticodon mismatches. J.Biol.Chem., 299, 2023
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8FMW
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![BU of 8fmw by Molmil](/molmil-images/mine/8fmw) | The structure of a hibernating ribosome in the Lyme disease pathogen | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Sharma, M.R, Manjari, S.R, Agrawal, E.K, Keshavan, P, Koripella, R.K, Majumdar, S, Marcinkiewicz, A.L, Lin, Y.P, Agrawal, R.K, Banavali, N.K. | 登録日 | 2022-12-25 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | The structure of a hibernating ribosome in a Lyme disease pathogen. Nat Commun, 14, 2023
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8G38
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![BU of 8g38 by Molmil](/molmil-images/mine/8g38) | Time-resolved cryo-EM study of the 70S recycling by the HflX:3rd Intermediate | 分子名称: | 16S, 23S, 30S ribosomal protein S10, ... | 著者 | Bhattacharjee, S, Brown, P.Z, Frank, J. | 登録日 | 2023-02-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G31
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![BU of 8g31 by Molmil](/molmil-images/mine/8g31) | Time-resolved cryo-EM study of the 70S recycling by the HflX:2nd Intermediate | 分子名称: | 16S, 23S, 30S ribosomal protein S10, ... | 著者 | Bhattacharjee, S, Brown, P.Z, Frank, J. | 登録日 | 2023-02-06 | 公開日 | 2023-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G2U
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![BU of 8g2u by Molmil](/molmil-images/mine/8g2u) | Time-resolved cryo-EM study of the 70S recycling by the HflX:control-apo-70S at 900ms | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Bhattacharjee, S, Brown, P.Z, Frank, J. | 登録日 | 2023-02-06 | 公開日 | 2023-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G34
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![BU of 8g34 by Molmil](/molmil-images/mine/8g34) | Time-resolved cryo-EM study of the 70S recycling by the HflX:1st intermediate | 分子名称: | 16S, 23S, 30S ribosomal protein S10, ... | 著者 | Bhattacharjee, S, Brown, P.Z, Frank, J. | 登録日 | 2023-02-06 | 公開日 | 2023-12-06 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling. Cell, 187, 2024
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8G4S
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![BU of 8g4s by Molmil](/molmil-images/mine/8g4s) | 40S ribosomal subunit of the 80S Giardia intestinalis assemblage A ribosome with Emetine bound in V2 conformation with mRNA and three tRNAs. | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... | 著者 | Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. | 登録日 | 2023-02-10 | 公開日 | 2024-01-31 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
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8G7S
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![BU of 8g7s by Molmil](/molmil-images/mine/8g7s) | |
8G7Q
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![BU of 8g7q by Molmil](/molmil-images/mine/8g7q) | |
8G7R
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![BU of 8g7r by Molmil](/molmil-images/mine/8g7r) | |
8G7P
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![BU of 8g7p by Molmil](/molmil-images/mine/8g7p) | |
6MPF
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![BU of 6mpf by Molmil](/molmil-images/mine/6mpf) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-10-05 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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6MTD
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![BU of 6mtd by Molmil](/molmil-images/mine/6mtd) | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | 登録日 | 2018-10-19 | 公開日 | 2018-11-21 | 最終更新日 | 2019-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MTE
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![BU of 6mte by Molmil](/molmil-images/mine/6mte) | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | 登録日 | 2018-10-19 | 公開日 | 2018-11-21 | 最終更新日 | 2019-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6N1D
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![BU of 6n1d by Molmil](/molmil-images/mine/6n1d) | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric Hybrid State | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Noller, H.F, Donohue, J.P, Lancaster, L, Zhou, J. | 登録日 | 2018-11-08 | 公開日 | 2019-04-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Spontaneous ribosomal translocation of mRNA and tRNAs into a chimeric hybrid state. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6N9E
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![BU of 6n9e by Molmil](/molmil-images/mine/6n9e) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | 登録日 | 2018-12-03 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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6N9F
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![BU of 6n9f by Molmil](/molmil-images/mine/6n9f) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | 登録日 | 2018-12-03 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res., 47, 2019
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6ND5
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![BU of 6nd5 by Molmil](/molmil-images/mine/6nd5) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | 登録日 | 2018-12-13 | 公開日 | 2019-03-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition. RNA, 25, 2019
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6NQB
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6ND4
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![BU of 6nd4 by Molmil](/molmil-images/mine/6nd4) | Conformational switches control early maturation of the eukaryotic small ribosomal subunit | 分子名称: | 18S rRNA 5' domain start, 5'ETS rRNA, Bud21, ... | 著者 | Hunziker, M, Barandun, J, Klinge, S. | 登録日 | 2018-12-13 | 公開日 | 2019-06-19 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Elife, 8, 2019
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6NTA
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![BU of 6nta by Molmil](/molmil-images/mine/6nta) | Modified ASL proline bound to Thermus thermophilus 70S (cognate) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | 登録日 | 2019-01-28 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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6NY6
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![BU of 6ny6 by Molmil](/molmil-images/mine/6ny6) | Structure of dimeric Escherichia coli toxin YoeB bound to the Thermus thermophilus 30S ribosome | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Pavelich, I.J, Hoffer, E.D, Maehigashi, T, Dunham, C.M. | 登録日 | 2019-02-11 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | 主引用文献 | Monomeric YoeB toxin retains RNase activity but adopts an obligate dimeric form for thermal stability. Nucleic Acids Res., 47, 2019
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