PDB: 2579 件ウェブページステータス検索Chemie searchBIRD

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6YX3	Crystal structure of SAICAR Synthetase (PurC) from Mycobacterium abscessus in complex with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Phosphoribosylaminoimidazole-succinocarboxamide synthase, ... 著者 Thomas, S.E, Charoensutthivarakul, S, Coyne, A.G, Abell, C, Blundell, T.L. 登録日 2020-04-30 公開日 2021-05-12 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.22 Å) 主引用文献 Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach. Acs Infect Dis., 8, 2022
1DAH	DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7,8-DIAMINO-NONANOIC ACID, 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE, AND MANGANESE 分子名称: 7,8-DIAMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, MANGANESE (II) ION, ... 著者 Huang, W, Jia, J, Schneider, G, Lindqvist, Y. 登録日 1995-05-08 公開日 1996-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
1DAI	DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID 分子名称: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE 著者 Huang, W, Jia, J, Schneider, G, Lindqvist, Y. 登録日 1995-05-08 公開日 1996-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
6HXQ	Structure of citryl-CoA synthetase from Hydrogenobacter thermophilus 分子名称: CITRATE ANION, COENZYME A, Citryl-CoA synthetase large subunit, ... 著者 Verstraete, K, Verschueren, K. 登録日 2018-10-17 公開日 2019-04-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
1DAG	DETHIOBIOTIN SYNTHETASE COMPLEXED WITH 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID AND 5'-ADENOSYL-METHYLENE-TRIPHOSPHATE 分子名称: 7-(CARBOXYAMINO)-8-AMINO-NONANOIC ACID, DETHIOBIOTIN SYNTHETASE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER 著者 Huang, W, Jia, J, Schneider, G, Lindqvist, Y. 登録日 1995-05-08 公開日 1996-06-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Mechanism of an ATP-dependent carboxylase, dethiobiotin synthetase, based on crystallographic studies of complexes with substrates and a reaction intermediate. Biochemistry, 34, 1995
8GIT	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 1mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIS	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.5mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIO	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.1mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIR	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.2mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-04-17 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
3MBI	Crystal structure of the phosphoribosylpyrophosphate (PRPP) synthetase from Thermoplasma volcanium in complex with ADP-Mg2+ and ribose 5-phosphate 分子名称: 5-O-phosphono-alpha-D-ribofuranose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Cherney, L.T, Cherney, M.M, Garen, C.R, James, M.N.G. 登録日 2010-03-25 公開日 2011-04-20 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The structures of Thermoplasma volcanium phosphoribosyl pyrophosphate synthetase bound to ribose-5-phosphate and ATP analogs. J.Mol.Biol., 413, 2011
6M2O	Double mutant(H333A/I334A) crystal structure of benzoate coenzyme A ligase 分子名称: Benzoate-coenzyme A ligase 著者 Li, T.L, Adhikari, K. 登録日 2020-02-28 公開日 2021-01-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Chemoenzymatic Synthesis and Biological Evaluation for Bioactive Molecules Derived from Bacterial Benzoyl Coenzyme A Ligase and Plant Type III Polyketide Synthase. Biomolecules, 10, 2020
7F5V	Drosophila P5CS filament with glutamate, ATP, and NADPH 分子名称: Delta-1-pyrroline-5-carboxylate synthase 著者 Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. 登録日 2021-06-22 公開日 2022-04-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis of dynamic P5CS filaments. Elife, 11, 2022
5D6J	Crystal structure of a mycobacterial protein 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Acyl-CoA synthase, MAGNESIUM ION, ... 著者 Li, W.J, Bi, L.J. 登録日 2015-08-12 公開日 2016-03-02 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria. Sci Rep, 5, 2015
7CPY	Lovastatin nonaketide synthase with LovC 分子名称: Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... 著者 Wang, J, Wang, Z. 登録日 2020-08-08 公開日 2021-01-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
2HVY	Crystal structure of an H/ACA box RNP from Pyrococcus furiosus 分子名称: 50S ribosomal protein L7Ae, ADENOSINE-5'-TRIPHOSPHATE, H/ACA RNA, ... 著者 Ye, K. 登録日 2006-07-31 公開日 2006-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of an H/ACA box ribonucleoprotein particle Nature, 443, 2006
7CPX	Lovastatin nonaketide synthase 分子名称: Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Wang, J, Wang, Z. 登録日 2020-08-08 公開日 2021-01-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
6DT1	Crystal structure of the ligase from bacteriophage T4 complexed with DNA intermediate 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ... 著者 Shi, K, Aihara, H. 登録日 2018-06-14 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction. Nucleic Acids Res., 46, 2018
8GIM	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIP	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.040mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8GIN	Structure of Ternary Complex of mouse cGAS with dsDNA and Bound ATP: with 10mM Mg2+ and 0.015mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-03-14 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
8G1J	Structure of Ternary Complex of cGAS with dsDNA and Bound ATP and ITP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wu, S, Sohn, J. 登録日 2023-02-02 公開日 2024-05-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
7TXU	Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 with ATP and 16x(Asp-Arg) 分子名称: 16x(Asp-Arg), ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase, ... 著者 Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. 登録日 2022-02-09 公開日 2022-06-01 最終更新日 2022-07-13 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 A cryptic third active site in cyanophycin synthetase creates primers for polymerization Nat Commun, 13, 2022
7TXV	Cyanophycin synthetase 1 from Synechocystis sp. UTEX2470 E82Q with ATP and 16x(Asp-Arg) 分子名称: 16x(Asp-Arg), ADENOSINE-5'-TRIPHOSPHATE, Cyanophycin synthase, ... 著者 Sharon, I, Grogg, M, Hilvert, D, Schmeing, T.M. 登録日 2022-02-09 公開日 2022-06-01 最終更新日 2022-07-13 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 A cryptic third active site in cyanophycin synthetase creates primers for polymerization Nat Commun, 13, 2022
6JP9	Crsytal structure of a XMP complexed ATPPase subunit of M. jannaschii GMP synthetase 分子名称: GMP synthase [glutamine-hydrolyzing] subunit B, MALONIC ACID, TRIETHYLENE GLYCOL, ... 著者 Shivakumarasamy, S, Balaram, H. 登録日 2019-03-26 公開日 2020-04-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Mechanistic Insights into the Functioning of a Two-Subunit GMP Synthetase, an Allosterically Regulated, Ammonia Channeling Enzyme. Biochemistry, 61, 2022
8GYM	Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... 著者 Wu, M.C, Hu, Y.Q, Han, F.Z, Zhou, L. 登録日 2022-09-23 公開日 2023-06-14 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Structures of Tetrahymena thermophila respiratory megacomplexes on the tubular mitochondrial cristae. Nat Commun, 14, 2023

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