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7RUU
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Structure of Human ATP:Cobalamin Adenosyltransferase R190C bound to adenosylcobalamin
分子名称: 5'-DEOXYADENOSINE, ACETATE ION, COBALAMIN, ...
著者Mascarenhas, R, Gouda, H, Koutmos, M, Banerjee, R.
登録日2021-08-18
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions.
J.Biol.Chem., 297, 2021
7RUT
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Structure of Human ATP:Cobalamin Adenosyltransferase R190C bound to ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Corrinoid adenosyltransferase, GLYCEROL, ...
著者Mascarenhas, R, Gouda, H, Koutmos, M, Banerjee, R.
登録日2021-08-18
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions.
J.Biol.Chem., 297, 2021
2RNA
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Itk SH3 average minimized
分子名称: Tyrosine-protein kinase ITK/TSK
著者Severin, A.J.
登録日2007-12-08
公開日2007-12-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure note: murine Itk SH3 domain
To be Published
5HXC
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BU of 5hxc by Molmil
Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 20 mM Na+ and zero Ca2+
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE, CALCIUM ION, ...
著者Liao, J, Jiang, Y.X, Faraldo-Gomez, J.D.
登録日2016-01-30
公開日2016-05-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger
Nat.Struct.Mol.Biol., 23, 2016
7RUV
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Structure of Human ATP:Cobalamin Adenosyltransferase E193K bound to adenosylcobalamin
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Corrinoid adenosyltransferase, ...
著者Mascarenhas, R, Gouda, H, Koutmos, M, Banerjee, R.
登録日2021-08-18
公開日2021-11-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions.
J.Biol.Chem., 297, 2021
2RND
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BU of 2rnd by Molmil
Structure of the N-terminal BARpeptide in DPC micelles
分子名称: Myc box-dependent-interacting protein 1
著者Loew, C, Weininger, U, Balbach, J.
登録日2007-12-16
公開日2008-10-14
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure and dynamics of helix-0 of the N-BAR domain in lipid micelles and bilayers
Biophys.J., 95, 2008
6XS6
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BU of 6xs6 by Molmil
SARS-CoV-2 Spike D614G variant, minus RBD
分子名称: Spike glycoprotein
著者Wang, X, Egri, S.B, Dudkina, N, Luban, J, Shen, K.
登録日2020-07-15
公開日2020-07-22
最終更新日2020-11-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.
Cell, 183, 2020
2RNJ
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NMR Structure of The S. Aureus VraR DNA Binding Domain
分子名称: Response regulator protein vraR
著者Donaldson, L.W.
登録日2008-01-09
公開日2008-01-22
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献The NMR Structure of the Staphylococcus aureus Response Regulator VraR DNA Binding Domain Reveals a Dynamic Relationship between It and Its Associated Receiver Domain
Biochemistry, 47, 2008
5HW7
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Candida albicans FKBP12 apo protein in P21212 space group
分子名称: FK506-binding protein 1
著者Tonthat, N.K, Schumacher, M.A.
登録日2016-01-28
公開日2016-09-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.291 Å)
主引用文献Structures of Pathogenic Fungal FKBP12s Reveal Possible Self-Catalysis Function.
Mbio, 7, 2016
2RI5
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BU of 2ri5 by Molmil
Crystal structure of the 3-MBT repeats from human L3MBTL1 with N358A point mutation
分子名称: DI(HYDROXYETHYL)ETHER, Lethal(3)malignant brain tumor-like protein, TRIETHYLENE GLYCOL
著者Li, H, Patel, D.J.
登録日2007-10-10
公開日2007-12-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Lower Lysine Methylation State-Specific Readout by MBT Repeats of L3MBTL1 and an Engineered PHD Finger.
Mol.Cell, 28, 2007
7SEX
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M. tb EgtD in complex with TGX221
分子名称: 7-methyl-2-morpholin-4-yl-9-[(1~{R})-1-phenylazanylethyl]-3~{H}-pyrido[1,2-a]pyrimidin-4-one, GLYCEROL, Histidine N-alpha-methyltransferase
著者Sudasinghe, T.D, Ronning, D.R.
登録日2021-10-02
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production.
Sci Rep, 11, 2021
2RNQ
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Solution structure of the C-terminal acidic domain of TFIIE alpha
分子名称: Transcription initiation factor IIE subunit alpha
著者Okuda, M, Nishimura, Y.
登録日2008-01-31
公開日2008-04-01
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH
Embo J., 27, 2008
2G97
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BU of 2g97 by Molmil
Crystal Structure of Visfatin/Pre-B Cell Colony Enhancing Factor 1/Nicotinamide Phosphoribosyltransferase In Complex with the Specific Inhibitor FK-866
分子名称: (2E)-N-{4-[1-(benzenecarbonyl)piperidin-4-yl]butyl}-3-(pyridin-3-yl)prop-2-enamide, Nicotinamide phosphoribosyltransferase
著者Kim, M.-K, Eom, S.H.
登録日2006-03-05
公開日2006-08-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of Visfatin/Pre-B Cell Colony-enhancing Factor 1/Nicotinamide Phosphoribosyltransferase, Free and in Complex with the Anti-cancer Agent FK-866
J.Mol.Biol., 362, 2006
2RO4
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BU of 2ro4 by Molmil
RDC-refined Solution Structure of the N-terminal DNA Recognition Domain of the Bacillus subtilis Transition-state Regulator AbrB
分子名称: Transition state regulatory protein abrB
著者Sullivan, D.M, Bobay, B.G, Kojetin, D.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J.
登録日2008-03-08
公開日2008-11-11
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
7D4S
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BU of 7d4s by Molmil
apo-form cyclic trinucleotide synthase CdnD
分子名称: Cyclic AMP-AMP-GMP synthase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
5HXA
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BU of 5hxa by Molmil
Crystal structure of an UDP-forming alpha, alpha-terhalose-phosphate synthase from Burkholderia xenovorans
分子名称: 1,2-ETHANEDIOL, Alpha,alpha-trehalose-phosphate synthase (UDP-forming), GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2016-01-29
公開日2016-02-10
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of an UDP-forming alpha, alpha-terhalose-phosphate synthase from Burkholderia xenovorans
to be published
2ROG
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BU of 2rog by Molmil
Solution structure of Thermus thermophilus HB8 TTHA1718 protein in living E. coli cells
分子名称: Heavy metal binding protein
著者Sakakibara, D, Sasaki, A, Ikeya, T, Hamatsu, J, Koyama, H, Mishima, M, Mikawa, T, Waelchli, M, Smith, B.O, Shirakawa, M, Guentert, P, Ito, Y.
登録日2008-03-21
公開日2009-03-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Protein structure determination in living cells by in-cell NMR spectroscopy
Nature, 458, 2009
5HZ6
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FABP4 in complex with 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid
分子名称: 6-Chloro-2-isopropyl-4-(3-isopropyl-phenyl)-quinoline-3-carboxylic acid, Fatty acid-binding protein, adipocyte
著者Ehler, A, Rudolph, M.G.
登録日2016-02-02
公開日2016-12-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors.
Bioorg. Med. Chem. Lett., 26, 2016
7D4O
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BU of 7d4o by Molmil
cyclic trinucleotide synthase CdnD in complex with ATP and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase, ...
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
2GHD
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BU of 2ghd by Molmil
Conformational mobility in the active site of a heme peroxidase
分子名称: CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者Badyal, S.K, Joyce, M.G, Sharp, K.H, Raven, E.L, Moody, P.C.E.
登録日2006-03-27
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Conformational Mobility in the Active Site of a Heme Peroxidase.
J.Biol.Chem., 281, 2006
6XJF
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BU of 6xjf by Molmil
X-ray crystal structure of Pyrococcus furiosus general transcription factor TFE-alpha (SeMet labeled protein)
分子名称: Transcription factor E
著者Murakami, K.S, Jun, S.H.
登録日2020-06-23
公開日2020-07-08
最終更新日2021-01-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Direct binding of TFE alpha opens DNA binding cleft of RNA polymerase.
Nat Commun, 11, 2020
2R6R
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BU of 2r6r by Molmil
Aquifex aeolicus FtsZ
分子名称: Cell division protein ftsZ, GUANOSINE-5'-DIPHOSPHATE
著者Trambaiolo, D, Oliva, M.A, Lowe, J.
登録日2007-09-06
公開日2007-10-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into the conformational variability of FtsZ.
J.Mol.Biol., 373, 2007
2GHY
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BU of 2ghy by Molmil
Novel Crystal Form of the ColE1 Rom Protein
分子名称: Regulatory protein rop
著者Jang, S.B, Jeong, M.S, Carter, R.J, Holbrook, E.L, Comolli, L.R, Holbrook, S.R.
登録日2006-03-28
公開日2006-05-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Novel crystal form of the ColE1 Rom protein.
Acta Crystallogr.,Sect.D, 62, 2006
6XXE
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BU of 6xxe by Molmil
CryoEM structure of the type IV pilin PilA5 from Thermus thermophilus
分子名称: Uncharacterized protein
著者Neuhaus, A, Gold, V.A.M.
登録日2020-01-27
公開日2020-03-11
最終更新日2020-05-20
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium.
Nat Commun, 11, 2020
7SEY
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M. tb EgtD in complex with SGH
分子名称: 2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinoline-5-sulfonyl)-1,4-diazepan-1-yl]ethan-1-one, Histidine N-alpha-methyltransferase
著者Sudasinghe, T.D, Ronning, D.R.
登録日2021-10-02
公開日2021-12-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Inhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production.
Sci Rep, 11, 2021

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